Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   MPG47_RS04490 Genome accession   NZ_CP094095
Coordinates   945707..947491 (+) Length   594 a.a.
NCBI ID   WP_245015828.1    Uniprot ID   -
Organism   Helicobacter pylori strain Hpfe083     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 940707..952491
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MPG47_RS04460 (MPG47_04460) motB 941367..942134 (+) 768 WP_245015826.1 flagellar motor protein MotB -
  MPG47_RS04465 (MPG47_04465) - 942138..942575 (+) 438 WP_001031792.1 hypothetical protein -
  MPG47_RS04470 (MPG47_04470) - 942756..944417 (+) 1662 WP_245015827.1 ABC transporter permease/substrate-binding protein -
  MPG47_RS04475 (MPG47_04475) - 944421..945062 (+) 642 WP_220938039.1 ATP-binding cassette domain-containing protein -
  MPG47_RS04480 (MPG47_04480) - 945074..945253 (-) 180 WP_000468796.1 hypothetical protein -
  MPG47_RS04485 (MPG47_04485) - 945245..945706 (+) 462 WP_000437191.1 hypothetical protein -
  MPG47_RS04490 (MPG47_04490) uvrC 945707..947491 (+) 1785 WP_245015828.1 excinuclease ABC subunit UvrC Machinery gene
  MPG47_RS04495 (MPG47_04495) - 947502..948767 (+) 1266 WP_000746802.1 homoserine dehydrogenase -
  MPG47_RS04500 (MPG47_04500) - 948768..949112 (+) 345 WP_001211660.1 YraN family protein -
  MPG47_RS04505 (MPG47_04505) trxA 949201..949521 (+) 321 WP_000020195.1 thioredoxin -
  MPG47_RS04510 (MPG47_04510) trxB 949527..950462 (+) 936 WP_120945573.1 thioredoxin-disulfide reductase -
  MPG47_RS04515 (MPG47_04515) - 950629..951450 (+) 822 WP_245015829.1 glycosyltransferase family 25 protein -
  MPG47_RS04520 (MPG47_04520) - 951647..951895 (-) 249 WP_000790556.1 RNA-binding protein -

Sequence

Protein


Download         Length: 594 a.a.        Molecular weight: 68487.65 Da        Isoelectric Point: 9.4829

>NTDB_id=666776 MPG47_RS04490 WP_245015828.1 945707..947491(+) (uvrC) [Helicobacter pylori strain Hpfe083]
MADLLSSLKNLSHSSGVYQYFDKNRQLLYIGKAKNLKKRIKSYFSVCNNEITPNHRASLRIQMMVKQIAFLETILVENEQ
DALILENSLIKQLKPKYNILLRDDKTYPYIYMDFSTDFPIPLITRKILKQPGVKYFGPFTSGAKDILDSLYELLPLVQKK
NCIKDKKACMFYQIERCKAPCENKITKEEYSKIAKECLEMIENKDKLIKELELKMERLSNNLRFEEALIYRDRIAKIQKI
APFTCMDLAKLYDLDIFAFYSGGNKAVLVKMFMRGGKIISSAFEKIHSLNGFDTDEAMKQAIINHYQSHLPLMPEQILLN
ACSNETLKELQDFISHQYSKKIALSIPKKGDKLALIEIAMKNAQEIFSQEKTSSEDLILEEAQSLFQLECMPYRVEIFDT
SHHANSQCVGGMVVYENHAFQKNSYRCYHLKGSNEYTQMSELLTRRALDFAKEPPPNLWVIDGGRAQLNIALEILKSSGS
FVEVIAISKEKRDSKAYRSKGGAKDIIHTANDTFKLLPSDKRLQWVQKLRDESHRYAINFHRSTKLKNMKQIALLKEKGI
GEASVKKLLDYFGSFEAIEKASEQEKNAVLKKRI

Nucleotide


Download         Length: 1785 bp        

>NTDB_id=666776 MPG47_RS04490 WP_245015828.1 945707..947491(+) (uvrC) [Helicobacter pylori strain Hpfe083]
ATGGCTGATTTATTGTCCAGTTTGAAAAACCTTTCTCACAGCAGTGGCGTGTATCAATATTTTGATAAAAACCGCCAATT
GCTCTATATCGGTAAGGCGAAAAATTTAAAAAAGCGCATCAAAAGTTATTTTTCTGTCTGTAATAATGAAATCACGCCCA
ATCATCGCGCAAGCCTACGCATCCAAATGATGGTCAAACAGATCGCTTTTTTAGAAACCATTTTAGTGGAAAACGAGCAA
GACGCTTTGATTTTAGAAAATTCTTTAATCAAACAGCTCAAGCCCAAATACAACATTCTTTTAAGAGACGATAAAACTTA
CCCTTATATTTACATGGATTTTTCCACTGATTTCCCTATCCCTTTAATCACACGAAAAATTTTAAAACAGCCTGGCGTTA
AATATTTTGGCCCTTTTACGAGCGGGGCTAAGGATATTTTAGACAGCTTGTATGAATTGCTCCCGTTAGTTCAAAAGAAA
AATTGCATCAAAGATAAAAAGGCATGCATGTTTTATCAAATAGAGCGTTGTAAAGCCCCATGCGAGAATAAAATCACCAA
AGAAGAGTATTCAAAAATCGCTAAAGAATGTTTGGAAATGATTGAAAATAAAGACAAACTCATCAAAGAGCTTGAATTAA
AAATGGAGCGCCTTTCTAATAACTTGCGTTTTGAAGAAGCCCTCATTTATAGGGATAGGATTGCAAAAATCCAAAAAATC
GCCCCTTTCACTTGCATGGATTTAGCCAAACTCTATGATTTGGATATTTTTGCTTTTTATAGTGGGGGCAATAAGGCGGT
GTTAGTGAAAATGTTTATGCGTGGGGGTAAAATCATTTCTTCAGCGTTTGAAAAAATCCACTCTCTCAATGGGTTTGACA
CTGATGAAGCGATGAAACAAGCCATTATCAATCATTACCAATCGCATTTGCCTTTAATGCCAGAACAAATCTTATTGAAC
GCTTGCTCTAATGAAACGCTTAAAGAATTGCAAGATTTTATCTCTCATCAATACTCTAAAAAAATCGCTCTTAGTATTCC
TAAAAAAGGCGATAAGCTCGCTTTAATAGAAATCGCTATGAAAAACGCTCAAGAGATTTTTAGCCAAGAAAAAACCTCTA
GTGAAGATCTGATTTTAGAAGAAGCGCAATCGCTCTTTCAATTAGAGTGCATGCCTTATAGGGTGGAAATCTTTGACACA
AGCCACCATGCCAACAGCCAATGCGTGGGGGGAATGGTCGTGTATGAAAATCATGCATTTCAAAAAAACTCCTATCGGTG
CTACCATTTAAAAGGCTCTAATGAATACACTCAAATGAGCGAATTGCTCACCAGAAGGGCTTTAGATTTTGCCAAAGAGC
CGCCGCCTAATTTGTGGGTGATCGATGGAGGGAGGGCACAATTAAACATCGCTTTAGAAATTTTAAAAAGCAGCGGGAGT
TTTGTAGAAGTGATCGCTATTTCTAAAGAGAAAAGGGATTCTAAAGCTTATCGCTCTAAAGGGGGCGCTAAAGACATCAT
CCACACCGCTAACGATACTTTTAAATTGCTCCCTAGCGACAAGCGCTTGCAGTGGGTGCAAAAATTGCGCGATGAAAGCC
ACCGGTATGCGATAAACTTCCATAGATCCACTAAACTTAAAAACATGAAACAAATCGCTCTTTTGAAAGAAAAGGGTATA
GGAGAAGCCAGCGTGAAAAAATTATTGGATTATTTTGGGAGTTTTGAAGCGATAGAAAAAGCGAGCGAACAGGAAAAAAA
CGCTGTTTTAAAAAAACGAATCTAA

Domains

Predicted by InterproScan.

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(384-538)

UvrB/uvrC motif (UVR)

(205-239)

GIY-YIG catalytic domain (GIY-YIG)

(15-98)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

96.465

100

0.965