Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   MPG19_RS04780 Genome accession   NZ_CP094094
Coordinates   996796..998580 (+) Length   594 a.a.
NCBI ID   WP_245065706.1    Uniprot ID   -
Organism   Helicobacter pylori strain Hpfe084     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 991796..1003580
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MPG19_RS04745 (MPG19_04745) motA 991866..992639 (+) 774 WP_000366185.1 flagellar motor stator protein MotA -
  MPG19_RS04750 (MPG19_04750) motB 992642..993409 (+) 768 WP_001085307.1 flagellar motor protein MotB -
  MPG19_RS04755 (MPG19_04755) - 993413..993850 (+) 438 WP_001031792.1 hypothetical protein -
  MPG19_RS04760 (MPG19_04760) - 993950..995506 (+) 1557 WP_245065700.1 ABC transporter permease/substrate-binding protein -
  MPG19_RS04765 (MPG19_04765) - 995510..996151 (+) 642 WP_245065702.1 ABC transporter ATP-binding protein -
  MPG19_RS04770 (MPG19_04770) - 996163..996342 (-) 180 WP_000468796.1 hypothetical protein -
  MPG19_RS04775 (MPG19_04775) - 996334..996795 (+) 462 WP_245065704.1 hypothetical protein -
  MPG19_RS04780 (MPG19_04780) uvrC 996796..998580 (+) 1785 WP_245065706.1 excinuclease ABC subunit UvrC Machinery gene
  MPG19_RS04785 (MPG19_04785) - 998591..999856 (+) 1266 WP_245051331.1 homoserine dehydrogenase -
  MPG19_RS04790 (MPG19_04790) - 999857..1000201 (+) 345 WP_001211660.1 YraN family protein -
  MPG19_RS04795 (MPG19_04795) trxA 1000290..1000610 (+) 321 WP_000020199.1 thioredoxin -
  MPG19_RS04800 (MPG19_04800) trxB 1000616..1001551 (+) 936 WP_245065708.1 thioredoxin-disulfide reductase -
  MPG19_RS04805 (MPG19_04805) - 1001717..1002538 (+) 822 WP_245065710.1 glycosyltransferase family 25 protein -
  MPG19_RS04810 (MPG19_04810) - 1002743..1002991 (-) 249 WP_000790557.1 RNA-binding protein -

Sequence

Protein


Download         Length: 594 a.a.        Molecular weight: 68758.02 Da        Isoelectric Point: 9.5332

>NTDB_id=666759 MPG19_RS04780 WP_245065706.1 996796..998580(+) (uvrC) [Helicobacter pylori strain Hpfe084]
MADLLSSLKNLSHSSGVYQYFDKNRQLLYIGKAKNLKKRIKSYFSICNNEITPNHRASLRIQMMVKQIAFLETILVENEQ
DALILENSLIKQLKPKYNILLRDDKTYPYIYMDFSTDFPIPLITRKILKQPGVKYFGPFTSGAKDILDSLYELLPLVQKK
NCIKDKKACMFYQIERCKAPCENKITKEEYLKITKECLEMIENKDKLIKKLELKMECLSNNLRFEEALIYRDRIAKIQKI
APFTCMDLAKLYDLDIFAFYSGSNKAVLVKMFMRGGKIISSAFEKIHSLNGFDTDEAMKQAIINHYQSHLPLMPEQILLN
ACSNETLKELQEFISHKYSKKIALSIPKKGDKLALIEIAMKNAQEIFSQEETSNEDLILEEARSLFQLECMPYRVEIFDT
SHHANSQCVGGMVVYENHEFQKNSYRRYHLKGSNEYTQMSELLTRRALDFNKEPPPNLWVIDGGRAQLNIALEILKSSGS
FVEVIAISKEKRDSKAYRSKGGAKDIIHTANDTFKLLPSDKRLQWVQKLRDESHRYAINFHRSTKLKNMKQIALLKEKGI
GEASVKKLLDYFGSFEAIEKASEQEKNAVLKKRI

Nucleotide


Download         Length: 1785 bp        

>NTDB_id=666759 MPG19_RS04780 WP_245065706.1 996796..998580(+) (uvrC) [Helicobacter pylori strain Hpfe084]
ATGGCTGATTTATTGTCCAGTTTGAAAAACCTTTCTCATAGCAGTGGCGTGTATCAATATTTTGATAAAAACCGCCAATT
ACTCTATATCGGTAAGGCGAAAAATTTAAAAAAGCGCATCAAAAGCTATTTTTCTATCTGCAATAATGAAATCACGCCCA
ATCATCGCGCAAGCTTACGCATCCAAATGATGGTCAAACAGATCGCTTTTTTAGAAACCATTTTAGTGGAAAACGAGCAA
GACGCTTTGATTTTAGAAAACTCTTTAATCAAGCAGCTCAAACCCAAATACAACATTCTTTTAAGAGACGATAAAACTTA
CCCTTATATTTACATGGATTTTTCCACTGATTTCCCTATCCCTTTAATCACACGAAAAATTTTAAAACAGCCTGGCGTTA
AATATTTTGGCCCTTTTACGAGCGGGGCTAAAGATATTTTAGACAGCTTGTATGAATTGCTCCCGTTAGTTCAAAAGAAA
AATTGCATCAAAGATAAAAAGGCATGCATGTTTTATCAAATAGAGCGTTGTAAAGCCCCATGCGAAAATAAAATCACCAA
AGAAGAGTATTTGAAAATCACTAAAGAATGTTTAGAAATGATTGAAAATAAAGACAAACTCATCAAAAAGCTTGAATTAA
AAATGGAGTGCCTTTCTAATAACTTGCGTTTTGAAGAAGCCCTCATTTATAGGGATAGGATTGCAAAAATCCAAAAAATC
GCCCCTTTCACTTGCATGGATTTGGCCAAACTCTATGATTTGGATATTTTTGCTTTTTATAGTGGGAGCAATAAGGCGGT
GTTAGTGAAAATGTTTATGCGTGGGGGTAAAATCATTTCTTCAGCGTTTGAAAAAATCCACTCTCTCAATGGGTTTGACA
CTGATGAAGCGATGAAACAAGCTATTATCAATCATTACCAATCGCATTTGCCTTTAATGCCAGAACAAATCTTATTGAAC
GCTTGCTCTAATGAAACGCTTAAAGAATTGCAAGAATTTATCTCTCATAAATACTCTAAAAAAATCGCTCTTAGCATCCC
TAAAAAAGGCGATAAACTCGCTTTAATAGAAATCGCTATGAAAAACGCTCAAGAGATTTTTAGCCAAGAAGAAACCTCTA
ATGAAGATCTGATTTTAGAAGAAGCGCGATCGCTCTTTCAATTAGAGTGCATGCCTTATAGGGTGGAAATCTTTGACACA
AGCCACCATGCCAACAGCCAATGCGTGGGGGGAATGGTCGTGTATGAAAACCATGAATTTCAAAAAAACTCCTATCGGCG
CTACCATTTAAAAGGCTCTAATGAATACACTCAAATGAGCGAATTGCTCACCAGAAGGGCTTTAGATTTTAATAAAGAGC
CGCCACCTAATTTGTGGGTGATCGATGGAGGGAGGGCACAATTAAACATCGCTTTAGAAATTTTAAAAAGCAGCGGGAGT
TTTGTAGAAGTGATCGCTATTTCTAAAGAAAAAAGGGATTCTAAAGCTTATCGCTCTAAAGGGGGCGCTAAAGACATTAT
CCACACCGCTAACGATACTTTTAAATTGCTCCCTAGCGACAAGCGCTTGCAGTGGGTGCAAAAATTGCGCGATGAAAGCC
ACCGGTATGCGATAAACTTCCATAGATCCACTAAGCTTAAAAACATGAAACAAATCGCTCTTTTAAAAGAAAAGGGTATA
GGAGAAGCTAGCGTGAAAAAATTGTTGGATTATTTTGGAAGTTTTGAAGCGATAGAAAAAGCGAGTGAGCAGGAAAAAAA
CGCCGTTTTAAAAAAACGAATCTAA

Domains

Predicted by InterproScan.

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(385-538)

UvrB/uvrC motif (UVR)

(205-239)

GIY-YIG catalytic domain (GIY-YIG)

(15-98)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

96.465

100

0.965