Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   MPF97_RS03130 Genome accession   NZ_CP094093
Coordinates   651002..652786 (-) Length   594 a.a.
NCBI ID   WP_245103039.1    Uniprot ID   -
Organism   Helicobacter pylori strain Hpfe085     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 646002..657786
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MPF97_RS03100 (MPF97_03100) - 646590..646838 (+) 249 WP_000790557.1 RNA-binding protein -
  MPF97_RS03105 (MPF97_03105) - 647043..647864 (-) 822 WP_245103035.1 glycosyltransferase family 25 protein -
  MPF97_RS03110 (MPF97_03110) trxB 648031..648966 (-) 936 WP_017283641.1 thioredoxin-disulfide reductase -
  MPF97_RS03115 (MPF97_03115) trxA 648972..649292 (-) 321 WP_078252522.1 thioredoxin -
  MPF97_RS03120 (MPF97_03120) - 649381..649725 (-) 345 WP_156605275.1 YraN family protein -
  MPF97_RS03125 (MPF97_03125) - 649726..650991 (-) 1266 WP_245103037.1 homoserine dehydrogenase -
  MPF97_RS03130 (MPF97_03130) uvrC 651002..652786 (-) 1785 WP_245103039.1 excinuclease ABC subunit UvrC Machinery gene
  MPF97_RS03135 (MPF97_03135) - 652787..653248 (-) 462 WP_180410965.1 hypothetical protein -
  MPF97_RS03140 (MPF97_03140) - 653240..653419 (+) 180 WP_000468796.1 hypothetical protein -
  MPF97_RS03145 (MPF97_03145) - 653431..654072 (-) 642 WP_245103041.1 ATP-binding cassette domain-containing protein -
  MPF97_RS03150 (MPF97_03150) - 654074..655630 (-) 1557 WP_245103043.1 ABC transporter permease/substrate-binding protein -
  MPF97_RS03155 (MPF97_03155) - 655730..656167 (-) 438 WP_015428879.1 hypothetical protein -
  MPF97_RS03160 (MPF97_03160) motB 656171..656938 (-) 768 WP_245103045.1 flagellar motor protein MotB -
  MPF97_RS03165 (MPF97_03165) motA 656941..657714 (-) 774 WP_000366186.1 flagellar motor stator protein MotA -

Sequence

Protein


Download         Length: 594 a.a.        Molecular weight: 68847.18 Da        Isoelectric Point: 9.7497

>NTDB_id=666734 MPF97_RS03130 WP_245103039.1 651002..652786(-) (uvrC) [Helicobacter pylori strain Hpfe085]
MADLLSSLKNLSHSSGVYQYFDKNRQLLYIGKAKNLKKRIKNYFSIRNNEITPNHRASLRIQMMVKQIAFLETILVENEQ
DALILENSLIKQLKPKYNILLRDDKTYPYIYMDFSTDFPIPLITRKILKQPSVKYFGPFTSGAKDILDSLYELLPLVQKK
NCIKDKKACMFYQIERCKAPCENKITKEEYLKIAKECLEMIENKDRLIKELELKMERLSNNLRFEEALIYRDRIAKIQKI
APFTCMDLAKLYDLDIFAFYSGSNKAVLVKMFMRGGKIISSAFEKIHSLNGFDTDEAMKQAIINHYQSHLPLMPEQILLN
ACSNETLKELQEFISHKYSKKIALSIPKKGDKLALIEIAMKNAQEIFSQEKTSNEDLILEEARSLFKLECMPYRVEIFDV
SHHANSQCVGGMVVYENHEFQKNSYRRYHLKGSNEYTQMSELLTRRALDFAKEPPPNLWVIDGGRAQLNIALEILKSSGS
FVEVIAISKEKRDSKAYRSKGGAKDIIHTASDTFKLLPSDKRLQWVQKLRDESHRYAINFHRSTKLKNMKQIALLKEKGI
GEASVKKLLDYFGSFEAIEKASEQEKNAVLKKRI

Nucleotide


Download         Length: 1785 bp        

>NTDB_id=666734 MPF97_RS03130 WP_245103039.1 651002..652786(-) (uvrC) [Helicobacter pylori strain Hpfe085]
ATGGCTGATTTATTGTCCAGTTTGAAAAACCTTTCTCATAGCAGTGGCGTGTATCAATATTTTGATAAAAACCGCCAATT
ACTCTATATCGGTAAGGCGAAAAATTTAAAAAAGCGCATCAAAAACTATTTTTCCATCCGTAATAATGAAATCACGCCCA
ACCATCGCGCAAGCTTACGAATCCAAATGATGGTCAAACAGATCGCTTTTTTAGAAACCATTTTAGTGGAAAACGAGCAA
GACGCTTTGATTTTAGAAAATTCTTTAATCAAACAGCTCAAGCCCAAATACAACATTCTTTTAAGAGACGATAAAACTTA
CCCCTATATTTATATGGATTTTTCCACCGATTTCCCTATCCCTTTAATCACACGAAAAATTTTAAAACAGCCTAGCGTTA
AATATTTTGGCCCTTTTACGAGCGGGGCTAAGGATATTTTAGACAGCTTGTATGAATTGCTCCCGTTAGTTCAAAAGAAA
AATTGCATCAAGGATAAAAAGGCATGCATGTTTTATCAAATAGAGCGTTGCAAAGCCCCATGCGAGAATAAAATCACCAA
AGAAGAGTATTTAAAAATCGCTAAAGAATGTTTAGAAATGATTGAAAATAAAGACAGGCTCATCAAGGAGCTTGAATTAA
AAATGGAGCGCCTTTCTAACAACTTGCGTTTTGAAGAAGCCCTCATTTATAGGGACAGGATTGCAAAAATCCAAAAAATC
GCCCCCTTTACTTGCATGGATTTGGCCAAACTCTATGATTTGGATATTTTTGCTTTTTATAGTGGGAGCAATAAGGCGGT
GTTAGTGAAGATGTTTATGCGTGGGGGTAAAATCATTTCTTCAGCGTTTGAAAAAATCCACTCTCTCAACGGGTTTGACA
CTGATGAAGCGATGAAACAAGCCATTATCAATCATTACCAATCGCATTTGCCTTTAATGCCTGAACAGATTTTATTGAAC
GCTTGCTCTAATGAAACGCTTAAAGAATTGCAAGAATTTATCTCTCATAAATACTCTAAAAAAATCGCTCTTAGCATTCC
TAAAAAAGGCGATAAGCTCGCTTTAATAGAAATCGCTATGAAAAACGCTCAAGAGATTTTTAGCCAAGAAAAAACCTCTA
ATGAAGATCTGATTTTAGAAGAAGCGCGATCGCTCTTTAAATTAGAGTGCATGCCTTATAGGGTAGAAATCTTTGATGTA
AGCCACCATGCCAACAGCCAATGCGTGGGGGGAATGGTCGTGTATGAAAATCATGAATTTCAAAAAAACTCCTATCGGCG
CTACCATTTAAAAGGCTCTAATGAATACACTCAAATGAGCGAATTGCTCACCAGAAGGGCTTTAGATTTTGCTAAAGAGC
CACCGCCTAATTTGTGGGTGATCGATGGAGGGAGAGCGCAATTAAACATCGCTTTAGAAATTTTAAAAAGCAGCGGGAGT
TTTGTAGAAGTGATCGCTATTTCTAAAGAAAAAAGGGATTCTAAAGCTTATCGCTCCAAAGGAGGCGCTAAAGACATCAT
CCACACCGCTAGCGATACTTTTAAGTTGCTCCCTAGCGACAAGCGCTTGCAGTGGGTGCAAAAATTGCGCGATGAAAGCC
ACCGGTATGCGATAAACTTCCATAGATCCACTAAACTTAAAAACATGAAACAAATCGCGCTTTTAAAAGAAAAAGGTATA
GGAGAAGCTAGCGTGAAAAAATTGTTGGATTATTTTGGGAGTTTTGAAGCGATAGAAAAAGCGAGCGAGCAGGAAAAAAA
CGCCGTTTTAAAAAAACGAATCTAA

Domains

Predicted by InterproScan.

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(385-538)

UvrB/uvrC motif (UVR)

(205-239)

GIY-YIG catalytic domain (GIY-YIG)

(15-98)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

97.475

100

0.975