Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   MPF86_RS03130 Genome accession   NZ_CP094091
Coordinates   647916..649700 (-) Length   594 a.a.
NCBI ID   WP_245065116.1    Uniprot ID   -
Organism   Helicobacter pylori strain Hpfe088     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 642916..654700
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MPF86_RS03100 (MPF86_03100) - 643502..643750 (+) 249 WP_245065109.1 RNA-binding protein -
  MPF86_RS03105 (MPF86_03105) - 643956..644777 (-) 822 WP_245065111.1 glycosyltransferase family 25 protein -
  MPF86_RS03110 (MPF86_03110) trxB 644945..645880 (-) 936 WP_245065114.1 thioredoxin-disulfide reductase -
  MPF86_RS03115 (MPF86_03115) trxA 645886..646206 (-) 321 WP_000020202.1 thioredoxin -
  MPF86_RS03120 (MPF86_03120) - 646295..646639 (-) 345 WP_001211650.1 YraN family protein -
  MPF86_RS03125 (MPF86_03125) - 646640..647905 (-) 1266 WP_212882768.1 homoserine dehydrogenase -
  MPF86_RS03130 (MPF86_03130) uvrC 647916..649700 (-) 1785 WP_245065116.1 excinuclease ABC subunit UvrC Machinery gene
  MPF86_RS03135 (MPF86_03135) - 649701..650162 (-) 462 WP_039704604.1 hypothetical protein -
  MPF86_RS03140 (MPF86_03140) - 650154..650333 (+) 180 WP_000468796.1 hypothetical protein -
  MPF86_RS03145 (MPF86_03145) - 650345..650986 (-) 642 WP_245065118.1 ABC transporter ATP-binding protein -
  MPF86_RS03150 (MPF86_03150) - 650990..652651 (-) 1662 WP_245065119.1 ABC transporter permease/substrate-binding protein -
  MPF86_RS03155 (MPF86_03155) - 652832..653269 (-) 438 WP_001031792.1 hypothetical protein -
  MPF86_RS03160 (MPF86_03160) motB 653273..654040 (-) 768 WP_001085305.1 flagellar motor protein MotB -

Sequence

Protein


Download         Length: 594 a.a.        Molecular weight: 68793.01 Da        Isoelectric Point: 9.5817

>NTDB_id=666693 MPF86_RS03130 WP_245065116.1 647916..649700(-) (uvrC) [Helicobacter pylori strain Hpfe088]
MADLLSSLKSLSHSSGVYQYFDKNHQLLYIGKAKNLKKRIRSYFSIHNNEITPNCRTSLRIQMMVKQIAFLETILVENEQ
DALILENSLIKQLKPKYNILLRDDKTYPYIYMDFSTDFPIPLITRKILKQPGVKYFGPFTSGAKDILDSLYELLPLVQKK
NCIKDKKACMFYQIERCKAPCENKITKEEYLKIAKECLEMIENKDKLIKELELKMERLSNNLRFEEALIYRDRIAKIQKI
APFTCMDLAKLYDLDIFAFYSGSNKAVLVKMFMRGGKIISSAFEKIHSLNGFDTDEAMKQAIINHYQSHLPLMPEQILLN
ACSNETLKELQEFISHQYSKKIALSIPKKGDKLALIEIAMKNAQEIFSQEKTSNEDLILEEARSLFKLECMPYRVEIFDT
SHHANSQCVGGMVVYENHEFQKNSYRRYHLKGSNEYTQMSELLTRRALDFNKEPPPNLWVIDGGRAQLNIALEILKSSGS
FVEVIAISKEKRDSKAYRSKGGAKDIIHTANDTFKLLPSDKRLQWVQKLRDESHRYAINFHRSTKLKNMKQIALLKEKGI
GEASVKKLLDYFGSFEAIEKASEQEKNAVLKKRI

Nucleotide


Download         Length: 1785 bp        

>NTDB_id=666693 MPF86_RS03130 WP_245065116.1 647916..649700(-) (uvrC) [Helicobacter pylori strain Hpfe088]
ATGGCTGATTTATTGTCCAGTTTGAAAAGCCTTTCTCATAGCAGTGGCGTGTATCAATATTTTGATAAAAACCACCAATT
ACTCTATATCGGTAAGGCGAAAAATTTAAAAAAGCGCATCAGAAGCTATTTTTCTATCCACAATAATGAAATCACGCCCA
ATTGTCGCACAAGCTTACGCATCCAAATGATGGTCAAACAGATCGCTTTTTTAGAAACCATTTTAGTGGAAAACGAACAA
GACGCTTTGATTTTAGAAAATTCTTTAATCAAGCAGCTCAAGCCCAAATACAACATTCTTTTAAGAGACGATAAAACTTA
CCCTTATATTTACATGGATTTTTCCACTGATTTCCCTATCCCTTTAATCACACGAAAAATTTTAAAACAGCCTGGCGTTA
AATATTTTGGCCCTTTTACGAGCGGGGCTAAAGATATTTTAGACAGCTTATATGAATTGCTCCCGTTAGTTCAAAAGAAA
AATTGCATCAAAGACAAAAAGGCATGCATGTTTTATCAAATAGAGCGTTGTAAAGCCCCATGCGAGAATAAAATCACCAA
AGAAGAGTATTTGAAAATCGCTAAAGAATGTTTAGAAATGATTGAAAATAAAGACAAACTCATCAAAGAGCTTGAATTAA
AAATGGAGCGCCTTTCTAATAACTTGCGTTTTGAAGAAGCCCTCATTTATAGGGACAGGATTGCAAAAATCCAAAAAATC
GCCCCTTTCACTTGCATGGATTTAGCCAAACTCTATGATTTGGATATTTTTGCTTTTTATAGTGGGAGCAATAAGGCGGT
GTTAGTGAAAATGTTTATGCGTGGGGGTAAAATCATTTCTTCAGCGTTTGAAAAAATCCACTCTCTCAATGGGTTTGACA
CTGATGAAGCGATGAAACAAGCTATTATCAATCATTACCAATCGCATTTGCCTTTGATGCCAGAACAGATTTTATTGAAC
GCTTGCTCTAATGAAACGCTTAAAGAATTGCAAGAATTTATCTCTCATCAATACTCTAAAAAAATCGCTCTTAGCATTCC
TAAAAAAGGCGATAAGCTCGCTTTAATAGAAATCGCTATGAAAAACGCTCAAGAGATTTTTAGCCAAGAAAAAACCTCTA
ATGAAGATCTGATTTTAGAAGAAGCGCGATCGCTCTTTAAATTAGAGTGCATGCCTTATAGGGTGGAAATCTTTGACACA
AGCCACCATGCCAACAGCCAATGCGTGGGGGGAATGGTCGTGTATGAAAATCATGAATTTCAAAAAAACTCCTATCGGCG
CTACCATTTAAAAGGCTCTAACGAATACACTCAAATGAGCGAATTGCTCACCAGAAGGGCTTTAGATTTTAATAAAGAGC
CACCGCCTAATTTGTGGGTGATCGATGGAGGGAGGGCGCAATTAAACATCGCTTTAGAAATTTTAAAAAGCAGCGGGAGT
TTTGTAGAAGTGATCGCTATTTCTAAAGAAAAAAGGGATTCTAAAGCTTATCGCTCTAAAGGAGGCGCTAAAGACATTAT
CCACACCGCTAACGATACTTTTAAATTGCTCCCTAGCGACAAACGCTTGCAGTGGGTTCAAAAATTGCGCGATGAAAGCC
ACCGGTATGCAATAAACTTCCATAGATCCACTAAACTTAAAAACATGAAACAAATCGCTCTTTTAAAAGAAAAGGGCATA
GGAGAAGCCAGCGTGAAAAAATTGTTGGATTATTTTGGGAGTTTTGAAGCGATAGAAAAAGCGAGCGAGCAGGAAAAAAA
CGCCGTTTTAAAAAAACGAATCTAA

Domains

Predicted by InterproScan.

UvrB/uvrC motif (UVR)

(205-239)

GIY-YIG catalytic domain (GIY-YIG)

(15-98)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(385-538)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

96.633

100

0.966