Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   MPG40_RS03305 Genome accession   NZ_CP094088
Coordinates   685940..687724 (-) Length   594 a.a.
NCBI ID   WP_245064305.1    Uniprot ID   -
Organism   Helicobacter pylori strain Hpfe092     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 680940..692724
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MPG40_RS03275 (MPG40_03275) - 681545..681793 (+) 249 WP_000790557.1 RNA-binding protein -
  MPG40_RS03280 (MPG40_03280) - 681990..682811 (-) 822 WP_245064299.1 glycosyltransferase family 25 protein -
  MPG40_RS03285 (MPG40_03285) trxB 682969..683904 (-) 936 WP_096528296.1 thioredoxin-disulfide reductase -
  MPG40_RS03290 (MPG40_03290) trxA 683910..684230 (-) 321 WP_245064301.1 thioredoxin -
  MPG40_RS03295 (MPG40_03295) - 684319..684663 (-) 345 WP_001211669.1 YraN family protein -
  MPG40_RS03300 (MPG40_03300) - 684664..685929 (-) 1266 WP_245064303.1 homoserine dehydrogenase -
  MPG40_RS03305 (MPG40_03305) uvrC 685940..687724 (-) 1785 WP_245064305.1 excinuclease ABC subunit UvrC Machinery gene
  MPG40_RS03310 (MPG40_03310) - 687725..688186 (-) 462 WP_039704604.1 hypothetical protein -
  MPG40_RS03315 (MPG40_03315) - 688178..688357 (+) 180 WP_000468796.1 hypothetical protein -
  MPG40_RS03320 (MPG40_03320) - 688369..689010 (-) 642 WP_245064307.1 ATP-binding cassette domain-containing protein -
  MPG40_RS03325 (MPG40_03325) - 689014..690675 (-) 1662 WP_245064309.1 ABC transporter permease/substrate-binding protein -
  MPG40_RS03330 (MPG40_03330) - 690830..691267 (-) 438 WP_001031792.1 hypothetical protein -
  MPG40_RS03335 (MPG40_03335) motB 691271..692038 (-) 768 WP_154503091.1 flagellar motor protein MotB -

Sequence

Protein


Download         Length: 594 a.a.        Molecular weight: 68822.09 Da        Isoelectric Point: 9.6675

>NTDB_id=666651 MPG40_RS03305 WP_245064305.1 685940..687724(-) (uvrC) [Helicobacter pylori strain Hpfe092]
MADLLSSLKNLSHSSGVYQYFDKNRQLLYIGKAKNLKKRIKSYFSIHNNEITPNHRASLRIQMMVKQIAFLETILVENEQ
DALILENSLIKQLKPKYNILLRDDKTYPYIYMDFSTDFPIPLITRKILKQPGVKYFGPFTSGAKDILDSLYELLPLVQKK
NCIKDKKACMFYQIERCKAPCENKITKEEYLKIAKECLEMIENKDKLIKELELKMERLSNNLRFEEALIYRDRIAKIQKI
APFTCMDLAKLYDLDIFAFYSGSHKAVLVKMFMRGGKIISSAFEKIHSLNGFDTDEAMKQAIINHYQSHLPLMPEQILLN
ACSNETLKELQDFISHQYSKKIALSIPKKGDKLALIEIAMKNAQEIFSQEKTSNEDLILEEARSLFKLECMPYRVEIFDT
SHHANSQCVGGMVVYENHEFQKNSYRRYHLKGSNEYAQMSELLTRRALDFNKEPPPNLWVIDGGRVQLNIALEILKSSGS
FVEVIAISKEKRDSKAYRSKGGAKDIIHTANDTFKLLPSDKRLQWVQKLRDESHRYAINFHRSTKLKNMKQIALLKEKGI
GEASVKKLLDYFGSFEAIEKASEQEKNAVLKKRI

Nucleotide


Download         Length: 1785 bp        

>NTDB_id=666651 MPG40_RS03305 WP_245064305.1 685940..687724(-) (uvrC) [Helicobacter pylori strain Hpfe092]
ATGGCTGATTTATTGTCCAGTTTGAAAAACCTTTCTCATAGCAGTGGCGTGTATCAATATTTTGATAAAAACCGCCAATT
ACTCTATATCGGTAAGGCGAAAAATTTAAAAAAGCGCATCAAAAGCTATTTTTCTATCCACAATAATGAAATCACGCCCA
ATCATCGCGCAAGCTTACGAATCCAAATGATGGTCAAACAGATCGCTTTTTTAGAAACCATTTTAGTAGAAAACGAACAA
GACGCTTTGATTTTAGAAAATTCTTTAATCAAGCAGCTCAAGCCCAAATACAACATTCTTTTAAGAGACGATAAAACTTA
CCCTTATATTTATATGGATTTTTCCACTGATTTCCCTATCCCTTTAATCACACGAAAAATTTTAAAACAGCCTGGCGTTA
AATATTTTGGTCCTTTTACGAGCGGGGCTAAGGATATTTTAGACAGCTTGTATGAATTGCTCCCATTAGTTCAAAAGAAA
AATTGCATCAAAGATAAAAAGGCATGCATGTTTTATCAAATAGAGCGTTGTAAAGCCCCATGCGAGAATAAAATCACCAA
AGAAGAGTATTTGAAAATCGCTAAAGAATGTTTAGAAATGATTGAAAATAAAGACAAACTCATCAAAGAGCTTGAATTAA
AAATGGAACGCCTTTCTAATAACTTGCGTTTTGAAGAAGCTCTCATTTATAGGGATAGGATTGCAAAAATCCAAAAAATC
GCCCCTTTCACTTGCATGGATTTAGCCAAACTCTATGATTTGGATATTTTTGCTTTTTATAGTGGGAGCCATAAGGCGGT
GTTAGTGAAAATGTTTATGCGTGGGGGTAAAATCATTTCTTCAGCGTTTGAAAAAATCCACTCTCTCAATGGGTTTGACA
CTGATGAAGCGATGAAACAAGCCATTATCAATCATTACCAATCGCATTTGCCTTTGATGCCTGAACAGATTTTATTGAAC
GCTTGCTCTAATGAAACGCTTAAAGAATTGCAAGATTTTATCTCTCATCAATACTCTAAAAAAATCGCTCTTAGCATTCC
TAAAAAAGGCGATAAGCTCGCTTTAATAGAAATCGCTATGAAAAACGCTCAAGAGATTTTTAGCCAAGAAAAAACCTCTA
ATGAAGATCTGATTTTAGAAGAAGCGCGATCGCTCTTTAAATTAGAGTGCATGCCTTATAGGGTGGAAATCTTTGACACA
AGCCACCATGCCAACAGCCAATGCGTGGGGGGAATGGTCGTGTATGAAAATCATGAATTTCAAAAAAACTCCTATCGGCG
CTACCATTTAAAAGGCTCTAATGAATACGCTCAAATGAGCGAATTGCTCACCAGAAGGGCTTTAGATTTTAATAAAGAGC
CGCCGCCTAATTTGTGGGTGATCGATGGAGGGAGGGTGCAATTAAACATCGCTTTAGAAATTTTAAAAAGCAGTGGGAGT
TTTGTAGAAGTGATCGCTATTTCTAAAGAAAAAAGGGATTCTAAAGCTTATCGCTCTAAAGGGGGCGCTAAAGACATTAT
CCACACCGCTAACGATACTTTTAAATTACTCCCTAGCGACAAGCGCTTGCAGTGGGTGCAAAAATTGCGCGATGAAAGCC
ACCGGTATGCGATAAACTTCCATAGATCCACTAAACTTAAAAACATGAAACAAATCGCTCTTTTAAAAGAAAAGGGTATA
GGAGAAGCCAGCGTGAAAAAATTGTTGGATTATTTTGGGAGTTTTGAAGCGATAGAAAAAGCGAGCGAGCAGGAAAAAAA
CGCCGTTTTAAAAAAACGGATTTAA

Domains

Predicted by InterproScan.

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(385-538)

GIY-YIG catalytic domain (GIY-YIG)

(15-98)

UvrB/uvrC motif (UVR)

(205-239)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

96.801

100

0.968