Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   MPG55_RS03165 Genome accession   NZ_CP094083
Coordinates   646453..648237 (-) Length   594 a.a.
NCBI ID   WP_245029175.1    Uniprot ID   -
Organism   Helicobacter pylori strain Hpfe096     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 641453..653237
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MPG55_RS03135 (MPG55_03135) - 642045..642293 (+) 249 WP_120945577.1 RNA-binding protein -
  MPG55_RS03140 (MPG55_03140) - 642491..643312 (-) 822 WP_245029173.1 glycosyltransferase family 25 protein -
  MPG55_RS03145 (MPG55_03145) trxB 643479..644414 (-) 936 WP_024773194.1 thioredoxin-disulfide reductase -
  MPG55_RS03150 (MPG55_03150) trxA 644420..644740 (-) 321 WP_000020200.1 thioredoxin -
  MPG55_RS03155 (MPG55_03155) - 644832..645176 (-) 345 WP_001211650.1 YraN family protein -
  MPG55_RS03160 (MPG55_03160) - 645177..646442 (-) 1266 WP_000746796.1 homoserine dehydrogenase -
  MPG55_RS03165 (MPG55_03165) uvrC 646453..648237 (-) 1785 WP_245029175.1 excinuclease ABC subunit UvrC Machinery gene
  MPG55_RS03170 (MPG55_03170) - 648238..648699 (-) 462 WP_039704604.1 hypothetical protein -
  MPG55_RS03175 (MPG55_03175) - 648691..648870 (+) 180 WP_000468794.1 hypothetical protein -
  MPG55_RS03180 (MPG55_03180) - 648882..649523 (-) 642 WP_245029177.1 ATP-binding cassette domain-containing protein -
  MPG55_RS03185 (MPG55_03185) - 649527..651188 (-) 1662 WP_245029179.1 ABC transporter permease/substrate-binding protein -
  MPG55_RS03190 (MPG55_03190) - 651367..651804 (-) 438 WP_202167917.1 hypothetical protein -
  MPG55_RS03195 (MPG55_03195) motB 651808..652575 (-) 768 WP_171881034.1 flagellar motor protein MotB -

Sequence

Protein


Download         Length: 594 a.a.        Molecular weight: 68815.06 Da        Isoelectric Point: 9.7530

>NTDB_id=666586 MPG55_RS03165 WP_245029175.1 646453..648237(-) (uvrC) [Helicobacter pylori strain Hpfe096]
MADLLSSLKNLSHSSGVYQYFDKNRQLLYIGKAKNLKKRIRSYFSVRNNEITPNHRASLRIQMMVKQIAFLETILVENEQ
DALILENSLIKQLKPKYNILLRDDKTYPYIYMDFSTDFPIPLITRKILKQPGVKYFGPFTSGAKDILDSLYELLPLVQKK
NCIKDKKACMFYQIERCKAPCENKITKEEYSKIAKECLEMIENKDKLIKKLELKMERLSNNLRFEEALIYRDRIAKIQKI
APFTCMDLAKLYDLDIFAFYSGSHKAVLVKMFMRGGKIISSAFEKIHSLNGFDTDEAMKQAIINHYQSHLPLMPEQILLN
ACSNETLKELQDFISHQYSKKIALNIPKKGDKLALIEIAMKNAQEIFSQEKTSNEDLILEEVRSLFQLECMPYRVEIFDT
SHHANSQCVGGMVVYENHEFQKNSYRRYHLKGSNEYTQMSELLTRRALDFAKEPPPNLWVIDGGRAQLNIALEILKSSGS
FVEVIAISKEKRDSKAYRSKGGAKDIIHTASDTFKLLPSDKRLQWVQKLRDESHRYAINFHRSTKLKNMKQIALLKEKGI
GEASVKKLLDYFGSFEAIEKASEQEKNAVLKKRI

Nucleotide


Download         Length: 1785 bp        

>NTDB_id=666586 MPG55_RS03165 WP_245029175.1 646453..648237(-) (uvrC) [Helicobacter pylori strain Hpfe096]
ATGGCTGATTTGTTGTCCAGTTTGAAAAACCTTTCTCATAGCAGTGGCGTGTATCAATATTTTGATAAAAACCGCCAATT
ACTCTATATCGGTAAGGCGAAAAATTTAAAAAAGCGCATCAGAAGCTATTTTTCTGTCCGCAATAATGAAATCACGCCCA
ATCATCGTGCAAGCTTACGAATCCAAATGATGGTCAAACAGATCGCTTTTTTAGAAACCATTTTAGTGGAAAACGAGCAA
GACGCTTTGATTTTAGAAAATTCTTTAATCAAACAGCTCAAACCCAAATACAACATTCTTTTAAGAGATGATAAAACTTA
CCCTTATATTTATATGGATTTTTCCACTGATTTCCCTATCCCTTTAATCACACGAAAAATTTTAAAACAGCCTGGCGTTA
AATATTTTGGCCCTTTTACGAGCGGGGCTAAAGATATTTTAGACAGCTTGTATGAATTGCTCCCATTAGTTCAAAAGAAA
AATTGCATCAAAGATAAAAAGGCATGCATGTTTTATCAAATAGAGCGTTGTAAAGCCCCATGCGAGAATAAAATCACCAA
AGAAGAGTATTCAAAAATCGCTAAAGAATGTTTAGAAATGATTGAAAATAAAGACAAACTCATCAAAAAGCTTGAATTAA
AAATGGAGCGCCTTTCTAATAACTTGCGTTTTGAAGAAGCTCTCATTTATAGGGACAGGATTGCAAAAATCCAAAAAATC
GCCCCTTTCACTTGCATGGATTTAGCCAAACTCTATGATTTGGATATTTTTGCTTTTTATAGTGGGAGCCATAAGGCGGT
GTTAGTGAAAATGTTTATGCGTGGGGGTAAAATCATTTCTTCAGCGTTTGAAAAAATCCACTCTCTCAATGGGTTTGACA
CTGATGAAGCGATGAAACAAGCCATTATCAATCATTACCAATCGCATTTGCCTTTGATGCCTGAACAAATCTTATTGAAC
GCTTGCTCTAATGAAACGCTTAAAGAATTGCAAGATTTTATCTCTCACCAATACTCTAAAAAAATCGCTCTTAACATTCC
TAAAAAAGGCGATAAACTCGCTTTAATAGAAATCGCTATGAAAAACGCTCAAGAGATTTTTAGCCAAGAAAAAACCTCTA
ATGAAGATCTGATTTTAGAAGAAGTGCGATCGCTCTTTCAATTAGAGTGCATGCCTTATAGGGTGGAAATCTTTGACACA
AGCCACCATGCCAACAGCCAATGCGTGGGGGGAATGGTCGTGTATGAAAATCATGAATTTCAAAAAAACTCCTATCGGCG
CTACCATTTAAAAGGCTCTAATGAATACACTCAAATGAGCGAATTGCTCACCAGAAGGGCTTTAGATTTCGCCAAAGAAC
CACCGCCTAATTTGTGGGTGATCGATGGAGGGAGGGCGCAATTAAACATCGCTTTAGAAATTTTAAAAAGTAGCGGGAGT
TTTGTAGAAGTGATCGCTATTTCTAAAGAAAAAAGGGATTCTAAAGCTTATCGCTCTAAAGGGGGCGCTAAAGACATCAT
CCACACCGCTAGCGATACTTTTAAATTGCTCCCTAGCGACAAGCGCTTGCAATGGGTTCAAAAATTGCGCGATGAAAGCC
ACCGGTATGCGATAAACTTCCATAGATCCACTAAACTTAAAAACATGAAACAAATCGCTCTTTTAAAAGAAAAGGGTATA
GGAGAAGCCAGCGTGAAAAAATTATTGGATTATTTTGGGAGTTTTGAAGCGATAGAAAAAGCGAGCGAGCAGGAAAAAAA
CGCCGTTTTAAAAAAACGAATCTAA

Domains

Predicted by InterproScan.

GIY-YIG catalytic domain (GIY-YIG)

(15-98)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(385-538)

UvrB/uvrC motif (UVR)

(205-239)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

96.465

100

0.965