Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   MPG63_RS04795 Genome accession   NZ_CP094082
Coordinates   1012462..1014246 (+) Length   594 a.a.
NCBI ID   WP_245046742.1    Uniprot ID   -
Organism   Helicobacter pylori strain Hpfe097     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1007462..1019246
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MPG63_RS04765 (MPG63_04765) motB 1008126..1008893 (+) 768 WP_001085307.1 flagellar motor protein MotB -
  MPG63_RS04770 (MPG63_04770) - 1008897..1009334 (+) 438 WP_001031792.1 hypothetical protein -
  MPG63_RS04775 (MPG63_04775) - 1009513..1011174 (+) 1662 WP_245046741.1 ABC transporter permease/substrate-binding protein -
  MPG63_RS04780 (MPG63_04780) - 1011176..1011817 (+) 642 WP_180496055.1 ABC transporter ATP-binding protein -
  MPG63_RS04785 (MPG63_04785) - 1011829..1012008 (-) 180 WP_000468796.1 hypothetical protein -
  MPG63_RS04790 (MPG63_04790) - 1012000..1012461 (+) 462 WP_000437191.1 hypothetical protein -
  MPG63_RS04795 (MPG63_04795) uvrC 1012462..1014246 (+) 1785 WP_245046742.1 excinuclease ABC subunit UvrC Machinery gene
  MPG63_RS04800 (MPG63_04800) - 1014257..1015522 (+) 1266 WP_000746791.1 homoserine dehydrogenase -
  MPG63_RS04805 (MPG63_04805) - 1015523..1015867 (+) 345 WP_001211650.1 YraN family protein -
  MPG63_RS04810 (MPG63_04810) trxA 1015956..1016276 (+) 321 WP_000020199.1 thioredoxin -
  MPG63_RS04815 (MPG63_04815) trxB 1016282..1017217 (+) 936 WP_245046743.1 thioredoxin-disulfide reductase -
  MPG63_RS04820 (MPG63_04820) - 1017382..1018203 (+) 822 WP_245046744.1 glycosyltransferase family 25 protein -
  MPG63_RS04825 (MPG63_04825) - 1018409..1018657 (-) 249 WP_000790557.1 RNA-binding protein -

Sequence

Protein


Download         Length: 594 a.a.        Molecular weight: 68731.08 Da        Isoelectric Point: 9.6673

>NTDB_id=666568 MPG63_RS04795 WP_245046742.1 1012462..1014246(+) (uvrC) [Helicobacter pylori strain Hpfe097]
MADLLSSLKNLSHSSGVYQYFDKNRQLLYIGKAKNLKKRIKSYFSVRNNEITPNHRASLRIQMMVKQIAFLETILVENEQ
DALILENSLIKQLKPKYNILLRDDKTYPYIYMDFSTDFPIPLITRKILKQPGIKYFGPFTSGAKDILDSLYELLPLVQKK
NCIKDKKACMFYQIERCKAPCENKITKEEYLKIAKECLEMIENKDKLIKELELKMECLSNNLRFEEALIYRDRIAKIQKI
APFTCMDLAKLYDLDIFAFYGKGHKAVLVKMFMRGGKIISSAFEKIHSLNGFDTDEAMKQAIINHYQSHLPLMPEQILLN
ACSNETLKELQDFISHKYSKKIALSIPKKGDKLALIEIAMKNAQEIFSQEKTSNEDLILEEARSLFQLECMPYRVEIFDT
SHHANSQCVGGMVVYENHEFQKNSYRRYHLKGSNEYTQMSELLTRRALDFAKEPPPNLWVIDGGRAQLNIALEILKSSGS
FVEVIAISKEKRDSKAYRSKGGAKDIIHTASDTFKLLPSDKRLQWVQKLRDESHRYAINFHRSTKLKNMKQIALLKEKGI
GEASVKKLLDYFGSFEAIEKASEQEKNAVLKKRI

Nucleotide


Download         Length: 1785 bp        

>NTDB_id=666568 MPG63_RS04795 WP_245046742.1 1012462..1014246(+) (uvrC) [Helicobacter pylori strain Hpfe097]
ATGGCTGATTTATTGTCCAGTTTGAAAAACCTTTCTCATAGCAGTGGCGTGTATCAATATTTTGATAAAAACCGCCAATT
ACTCTATATCGGTAAGGCGAAAAATTTAAAAAAGCGCATCAAAAGTTATTTTTCTGTCCGTAATAATGAAATCACGCCCA
ATCATCGTGCAAGCTTACGAATCCAAATGATGGTCAAACAAATCGCTTTTTTAGAAACCATTTTAGTGGAAAACGAGCAA
GACGCTTTGATTTTAGAAAATTCTTTAATCAAGCAGCTCAAGCCCAAATACAACATTCTTTTAAGAGACGATAAAACTTA
CCCTTATATTTATATGGATTTTTCCACTGATTTCCCTATCCCTTTAATCACACGAAAAATTTTAAAACAGCCTGGCATTA
AATATTTTGGCCCTTTTACGAGCGGGGCTAAAGATATTTTAGACAGCTTGTATGAATTGCTCCCGTTAGTTCAAAAGAAA
AATTGCATCAAGGATAAAAAGGCGTGCATGTTTTATCAAATAGAGCGTTGTAAAGCCCCATGTGAGAATAAAATCACCAA
AGAAGAATATTTGAAAATCGCTAAAGAATGTTTAGAAATGATTGAAAATAAAGACAAACTCATCAAAGAGCTTGAATTAA
AAATGGAGTGCCTTTCTAATAACTTGCGTTTTGAAGAAGCCCTCATTTATAGGGATAGGATTGCAAAAATCCAAAAAATC
GCCCCTTTCACTTGCATGGATTTAGCCAAACTCTATGATTTGGATATTTTTGCTTTTTATGGCAAGGGCCATAAGGCGGT
GTTAGTGAAAATGTTTATGCGTGGGGGTAAAATCATTTCTTCAGCGTTTGAAAAAATCCACTCTCTTAATGGGTTTGACA
CTGATGAAGCGATGAAACAAGCCATTATCAATCATTACCAATCGCATTTGCCTTTAATGCCAGAACAGATTTTATTAAAC
GCTTGCTCTAATGAAACGCTTAAAGAATTGCAAGATTTTATCTCTCATAAATACTCTAAAAAAATCGCTCTTAGCATTCC
TAAAAAAGGCGATAAGCTCGCTTTGATAGAAATCGCTATGAAAAACGCTCAAGAGATTTTTAGCCAAGAAAAAACCTCTA
ATGAAGATCTGATTTTAGAAGAAGCGCGATCGCTCTTTCAATTAGAGTGCATGCCTTATAGGGTGGAAATCTTTGACACC
AGCCACCATGCCAACAGCCAATGCGTGGGGGGAATGGTCGTGTATGAAAATCATGAATTTCAAAAAAACTCCTATCGGCG
CTACCATTTAAAAGGCTCTAATGAATACACTCAAATGAGCGAATTGCTCACCAGAAGGGCTTTAGATTTTGCCAAAGAGC
CACCGCCTAATTTGTGGGTGATCGATGGAGGGAGGGCGCAATTAAACATCGCTTTAGAAATTTTAAAAAGCAGCGGGAGT
TTTGTAGAAGTGATCGCTATTTCTAAAGAAAAAAGGGATTCTAAAGCTTATCGCTCTAAAGGGGGCGCTAAAGACATTAT
CCACACCGCTAGCGATACTTTTAAATTGCTCCCTAGCGACAAGCGTTTGCAGTGGGTGCAAAAATTGCGCGATGAAAGCC
ACCGGTATGCGATAAACTTCCATAGATCCACTAAACTTAAAAACATGAAACAAATCGCTCTTTTAAAAGAAAAGGGTATA
GGAGAAGCCAGCGTGAAAAAATTGTTGGATTATTTTGGGAGTTTTGAAGCGATAGAAAAAGCGAGCGAGCAGGAAAAAAA
CGCCGTTTTAAAAAAACGAATCTAA

Domains

Predicted by InterproScan.

GIY-YIG catalytic domain (GIY-YIG)

(15-98)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(385-538)

UvrB/uvrC motif (UVR)

(205-239)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

96.801

100

0.968