Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   MPG38_RS04780 Genome accession   NZ_CP094080
Coordinates   1009188..1010972 (+) Length   594 a.a.
NCBI ID   WP_245100474.1    Uniprot ID   -
Organism   Helicobacter pylori strain Hpfe099     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1004188..1015972
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MPG38_RS04750 (MPG38_04750) motB 1004849..1005616 (+) 768 WP_001085316.1 flagellar motor protein MotB -
  MPG38_RS04755 (MPG38_04755) - 1005620..1006057 (+) 438 WP_021301757.1 hypothetical protein -
  MPG38_RS04760 (MPG38_04760) - 1006237..1007898 (+) 1662 WP_245100472.1 ABC transporter permease/substrate-binding protein -
  MPG38_RS04765 (MPG38_04765) - 1007902..1008543 (+) 642 WP_245100473.1 ATP-binding cassette domain-containing protein -
  MPG38_RS04770 (MPG38_04770) - 1008555..1008734 (-) 180 WP_000468796.1 hypothetical protein -
  MPG38_RS04775 (MPG38_04775) - 1008726..1009187 (+) 462 WP_000437191.1 hypothetical protein -
  MPG38_RS04780 (MPG38_04780) uvrC 1009188..1010972 (+) 1785 WP_245100474.1 excinuclease ABC subunit UvrC Machinery gene
  MPG38_RS04785 (MPG38_04785) - 1010983..1012248 (+) 1266 WP_245100476.1 homoserine dehydrogenase -
  MPG38_RS04790 (MPG38_04790) - 1012249..1012593 (+) 345 WP_245100478.1 YraN family protein -
  MPG38_RS04795 (MPG38_04795) trxA 1012682..1013002 (+) 321 WP_000020200.1 thioredoxin -
  MPG38_RS04800 (MPG38_04800) trxB 1013008..1013943 (+) 936 WP_000564427.1 thioredoxin-disulfide reductase -
  MPG38_RS04805 (MPG38_04805) - 1014109..1014930 (+) 822 WP_245100480.1 glycosyltransferase family 25 protein -
  MPG38_RS04810 (MPG38_04810) - 1015135..1015383 (-) 249 WP_000790557.1 RNA-binding protein -

Sequence

Protein


Download         Length: 594 a.a.        Molecular weight: 68774.00 Da        Isoelectric Point: 9.7159

>NTDB_id=666544 MPG38_RS04780 WP_245100474.1 1009188..1010972(+) (uvrC) [Helicobacter pylori strain Hpfe099]
MADLLSSLKNLSHSSGVYQYFDKNRQLLYIGKAKNLKKRIRSYFSVRNNEITPNHRASLRIQMMVKQIAFLETILVENEQ
DALILENSLIKQLKPKYNILLRDDKTYPYIYMDFSTDFPIPLITRKILKQPGVKYFGPFTSGAKDILDSLYELLPLVQKK
NCIKDKKACMFYQIERCKAPCENKITKEEYLKIAKECLEMIENKDKLIKELELKMERLSNNLRFEEALIYRNRIAKIQKI
APFTCMDLAKLYDLDIFAFYSESNKAVLVKMFMRGGKIISSAFEKIHSLNGFDTDEAMKQAIINHYQSHLPLMPEQILLN
ACSNETLKELQDFISHQYSKKIALSIPKKGDKLALIEIAMKNAQEIFSQEKTSNEDLILEEARSLFQLECMPYRVEIFDA
SHHANSQCVGGMVVYENHAFQKNSYRRYHLKGSNEYTQMSELLTRRALDFAKEPPPNLWVIDGGRAQLNIALEILKSSGS
FVEVIAISKEKRDSKAYRSKGGAKDIIHTANDTFKLLPSDKRLQWVQKLRDESHRYAINFHRSTKLKNMKQIALLKEKGI
GEASVKKLLDYFGSFEAIEKASEQEKNAVLKKRI

Nucleotide


Download         Length: 1785 bp        

>NTDB_id=666544 MPG38_RS04780 WP_245100474.1 1009188..1010972(+) (uvrC) [Helicobacter pylori strain Hpfe099]
ATGGCTGATTTATTGTCCAGTTTGAAAAACCTTTCTCATAGCAGTGGCGTGTATCAATATTTTGATAAAAACCGCCAATT
ACTCTATATCGGTAAGGCGAAAAATTTAAAAAAGCGCATCAGAAGCTATTTTTCTGTCCGCAATAATGAAATCACGCCCA
ATCATCGCGCAAGCTTACGCATCCAAATGATGGTCAAACAGATCGCTTTTTTAGAAACCATTTTAGTGGAAAACGAGCAA
GACGCTTTGATTTTAGAAAACTCTTTAATCAAGCAGCTCAAACCCAAATACAACATTCTTTTAAGAGATGATAAAACTTA
CCCTTATATTTATATGGATTTTTCCACTGATTTCCCTATCCCTTTAATCACACGAAAAATTTTAAAACAGCCTGGCGTTA
AATATTTTGGCCCTTTTACGAGTGGGGCTAAGGATATTTTAGACAGCTTGTATGAATTACTTCCGTTAGTTCAAAAGAAA
AATTGCATCAAAGATAAAAAGGCATGCATGTTTTATCAAATAGAGCGTTGTAAAGCCCCATGCGAGAATAAAATCACCAA
AGAAGAGTATTTAAAAATCGCTAAAGAATGTTTAGAAATGATTGAAAATAAAGACAAACTCATCAAAGAGCTTGAATTAA
AAATGGAGCGCCTTTCTAATAACTTGCGTTTTGAAGAAGCCCTAATTTATAGGAACAGGATTGCAAAAATCCAAAAAATC
GCCCCCTTTACTTGCATGGATTTAGCCAAACTCTATGATTTGGATATTTTTGCTTTTTATAGTGAGAGCAATAAGGCGGT
GTTAGTGAAAATGTTTATGCGTGGGGGTAAAATCATTTCTTCAGCGTTTGAAAAAATCCACTCTCTTAATGGGTTTGACA
CTGATGAAGCGATGAAACAAGCTATTATCAATCATTACCAATCGCATTTGCCTTTGATGCCTGAACAAATCTTATTGAAC
GCTTGCTCTAATGAAACGCTTAAAGAATTGCAAGATTTTATCTCTCATCAATACTCTAAAAAAATCGCTCTTAGCATTCC
TAAAAAAGGCGACAAGCTCGCTTTAATAGAAATCGCTATGAAAAACGCTCAAGAGATTTTTAGCCAAGAAAAAACCTCTA
ATGAAGATCTGATTTTAGAAGAAGCGCGATCGCTCTTTCAATTAGAGTGCATGCCTTATAGGGTGGAAATCTTTGATGCA
AGCCACCATGCCAACAGCCAATGCGTGGGGGGAATGGTCGTGTATGAAAACCATGCATTTCAAAAAAACTCCTATCGGCG
CTACCATTTAAAAGGCTCTAATGAATACACTCAAATGAGCGAATTGCTCACCAGAAGGGCTTTAGATTTTGCCAAAGAGC
CACCGCCTAATTTGTGGGTGATCGATGGAGGGAGGGCGCAATTAAACATCGCTTTAGAAATTTTAAAAAGCAGCGGGAGT
TTTGTAGAAGTGATCGCTATTTCTAAAGAAAAAAGGGATTCTAAAGCTTATCGCTCCAAAGGAGGCGCTAAAGACATTAT
CCACACCGCTAACGATACTTTTAAATTACTCCCTAGCGACAAGCGCTTGCAGTGGGTGCAAAAATTGCGCGATGAAAGCC
ACCGGTATGCGATAAACTTCCATAGATCCACTAAACTTAAAAACATGAAACAAATCGCTCTTTTAAAAGAAAAAGGCATA
GGAGAAGCCAGCGTGAAAAAATTGTTGGATTATTTTGGGAGTTTTGAAGCGATAGAAAAAGCGAGCGAGCAGGAAAAAAA
CGCTGTTTTAAAAAAACGAATCTAA

Domains

Predicted by InterproScan.

UvrB/uvrC motif (UVR)

(205-239)

GIY-YIG catalytic domain (GIY-YIG)

(15-98)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(385-538)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

96.97

100

0.97