Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   MPF83_RS04480 Genome accession   NZ_CP094078
Coordinates   941176..942960 (+) Length   594 a.a.
NCBI ID   WP_245053323.1    Uniprot ID   -
Organism   Helicobacter pylori strain Hpfe101     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 936176..947960
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MPF83_RS04450 (MPF83_04450) motB 936949..937716 (+) 768 WP_001085305.1 flagellar motor protein MotB -
  MPF83_RS04455 (MPF83_04455) - 937720..938157 (+) 438 WP_001031792.1 hypothetical protein -
  MPF83_RS04460 (MPF83_04460) - 938226..939887 (+) 1662 WP_245053318.1 ABC transporter permease/substrate-binding protein -
  MPF83_RS04465 (MPF83_04465) - 939891..940532 (+) 642 WP_245053320.1 ABC transporter ATP-binding protein -
  MPF83_RS04470 (MPF83_04470) - 940543..940722 (-) 180 WP_000468796.1 hypothetical protein -
  MPF83_RS04475 (MPF83_04475) - 940714..941175 (+) 462 WP_245053321.1 hypothetical protein -
  MPF83_RS04480 (MPF83_04480) uvrC 941176..942960 (+) 1785 WP_245053323.1 excinuclease ABC subunit UvrC Machinery gene
  MPF83_RS04485 (MPF83_04485) - 942971..944236 (+) 1266 WP_245053325.1 homoserine dehydrogenase -
  MPF83_RS04490 (MPF83_04490) - 944237..944581 (+) 345 WP_245053327.1 YraN family protein -
  MPF83_RS04495 (MPF83_04495) trxA 944670..944990 (+) 321 WP_033587185.1 thioredoxin -
  MPF83_RS04500 (MPF83_04500) trxB 944996..945931 (+) 936 WP_120945573.1 thioredoxin-disulfide reductase -
  MPF83_RS04505 (MPF83_04505) - 946099..946920 (+) 822 WP_245053329.1 glycosyltransferase family 25 protein -
  MPF83_RS04510 (MPF83_04510) - 947122..947370 (-) 249 WP_000790556.1 RNA-binding protein -

Sequence

Protein


Download         Length: 594 a.a.        Molecular weight: 68692.03 Da        Isoelectric Point: 9.6559

>NTDB_id=666503 MPF83_RS04480 WP_245053323.1 941176..942960(+) (uvrC) [Helicobacter pylori strain Hpfe101]
MADLLSSLKSLSHSSGVYQYFDKNRQLLYIGKAKNLKKRIKSYFSVRNNEITPNYRASLRIQMMVKQIAFLETILVENEQ
DALILENSLIKQLKPKYNILLRDDKTYPYIYMDFSTDFPIPLITRKILKQPGVKYFGPFTSGAKDILDSLYELLPLVQKK
NCIKDKKACMFYQIERCKAPCENKITKEEYLKIAKECLEMIENKDKLIKELELKMERLSSNLRFEEALIYRDRIAKIQKI
APFTCMDLAKLYDLDIFAFYSGSNKAVLVKMFMRGGKIISSAFEKIHSLNGFDTDEAMKQAIINHYQSHLPLMPEQILLN
ACSNKTLKELQEFISHQYSKKIALSIPKKGDKLALIEIAMKNAQEIFSQEKISNEDLILEEAQSLFKLECMPYRVEIFDA
SHHANSQCVGGMVVYENHEFQKNSYRCYHLKGSNEYTQMSELLTRRALDFNKEPPPNLWVIDGGRAQLNIALEILKSSGS
FVEVIAISKEKRDSKAYRSKGGAKDIIHTANDTFKLLPSDKRLQWVQKLRDESHRYAINFHRSTKLKNMKQIALLKEKGI
GEASVKKLLDYFGSFEAIEKASEQEKNAVLKKRI

Nucleotide


Download         Length: 1785 bp        

>NTDB_id=666503 MPF83_RS04480 WP_245053323.1 941176..942960(+) (uvrC) [Helicobacter pylori strain Hpfe101]
ATGGCTGATTTATTGTCCAGTTTAAAAAGCCTTTCTCATAGCAGTGGCGTGTATCAATATTTTGATAAAAACCGCCAGTT
ACTCTATATCGGTAAGGCGAAAAATTTAAAAAAGCGCATCAAAAGTTATTTTTCTGTCCGTAATAATGAAATCACGCCCA
ATTATCGCGCAAGCTTACGCATCCAAATGATGGTCAAACAGATCGCTTTTTTAGAAACCATTTTAGTGGAAAACGAGCAA
GACGCTTTGATTTTAGAAAATTCTTTAATCAAGCAGCTCAAACCCAAATACAACATTCTTTTAAGAGATGATAAAACTTA
CCCTTATATTTACATGGATTTTTCCACTGATTTCCCTATCCCTTTAATCACACGAAAAATTTTAAAACAGCCTGGCGTTA
AATATTTTGGCCCTTTTACGAGCGGGGCTAAGGATATTTTAGACAGCTTGTATGAATTGCTCCCGTTAGTTCAAAAGAAA
AATTGCATCAAAGATAAAAAGGCATGCATGTTTTATCAAATAGAGCGTTGTAAAGCCCCATGCGAGAATAAAATCACCAA
AGAAGAGTATTTGAAAATCGCTAAAGAATGTTTAGAAATGATTGAAAATAAAGACAAACTCATCAAAGAGCTTGAATTAA
AAATGGAGCGCCTTTCTAGCAATTTGCGTTTTGAAGAAGCTCTCATTTATAGGGATAGGATTGCAAAAATCCAAAAAATC
GCCCCTTTCACTTGCATGGATTTAGCCAAACTCTATGATTTGGATATTTTTGCTTTTTATAGTGGGAGCAATAAGGCGGT
ATTAGTGAAAATGTTTATGCGTGGGGGTAAAATCATTTCTTCAGCGTTTGAAAAAATCCACTCTCTCAATGGGTTTGACA
CTGATGAAGCGATGAAACAAGCTATTATCAATCATTACCAATCGCATTTGCCTTTGATGCCTGAACAGATTTTATTGAAC
GCTTGCTCTAATAAAACGCTTAAAGAATTGCAAGAATTTATTTCTCACCAATACTCTAAAAAAATCGCTCTTAGTATTCC
TAAAAAAGGCGACAAGCTCGCTTTAATAGAAATCGCTATGAAAAACGCTCAAGAGATTTTTAGCCAAGAAAAAATCTCTA
ATGAGGATCTGATTTTAGAAGAAGCGCAATCACTCTTTAAATTAGAGTGCATGCCTTATAGGGTGGAAATCTTTGATGCA
AGCCACCATGCCAACAGCCAATGCGTGGGGGGAATGGTCGTGTATGAAAATCATGAATTTCAAAAAAACTCCTATCGGTG
CTACCATTTAAAAGGCTCTAATGAATACACTCAAATGAGCGAATTGCTCACCAGAAGGGCTTTAGATTTTAATAAAGAGC
CACCGCCTAATTTGTGGGTGATCGATGGAGGGAGGGCGCAATTAAACATCGCTTTAGAAATTTTAAAAAGCAGCGGGAGT
TTTGTAGAAGTGATCGCTATTTCTAAAGAAAAAAGGGATTCTAAAGCTTATCGCTCCAAAGGAGGCGCTAAAGACATTAT
CCACACCGCTAACGATACTTTTAAATTGCTCCCTAGCGACAAGCGCTTGCAGTGGGTGCAAAAATTGCGCGATGAAAGCC
ACCGGTATGCGATAAACTTCCATAGATCCACTAAACTTAAAAACATGAAACAAATCGCTCTTTTAAAAGAAAAGGGTATA
GGAGAAGCCAGCGTGAAAAAATTATTGGATTATTTTGGGAGTTTTGAAGCGATAGAAAAAGCGAGCGAGCAGGAAAAAAA
CGCTGTTTTAAAAAAACGGATTTAA

Domains

Predicted by InterproScan.

GIY-YIG catalytic domain (GIY-YIG)

(15-98)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(384-538)

UvrB/uvrC motif (UVR)

(205-239)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

96.128

100

0.961