Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   MPG62_RS03255 Genome accession   NZ_CP094071
Coordinates   681248..683032 (-) Length   594 a.a.
NCBI ID   WP_245099911.1    Uniprot ID   -
Organism   Helicobacter pylori strain Hpfe106     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 676248..688032
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MPG62_RS03225 (MPG62_03225) - 676836..677084 (+) 249 WP_000790557.1 RNA-binding protein -
  MPG62_RS03230 (MPG62_03230) - 677290..678111 (-) 822 WP_245099908.1 glycosyltransferase family 25 protein -
  MPG62_RS03235 (MPG62_03235) trxB 678277..679212 (-) 936 WP_180672563.1 thioredoxin-disulfide reductase -
  MPG62_RS03240 (MPG62_03240) trxA 679218..679538 (-) 321 WP_000020199.1 thioredoxin -
  MPG62_RS03245 (MPG62_03245) - 679627..679971 (-) 345 WP_231168136.1 YraN family protein -
  MPG62_RS03250 (MPG62_03250) - 679972..681237 (-) 1266 WP_245099910.1 homoserine dehydrogenase -
  MPG62_RS03255 (MPG62_03255) uvrC 681248..683032 (-) 1785 WP_245099911.1 excinuclease ABC subunit UvrC Machinery gene
  MPG62_RS03260 (MPG62_03260) - 683033..683494 (-) 462 WP_245099913.1 hypothetical protein -
  MPG62_RS03265 (MPG62_03265) - 683486..683665 (+) 180 WP_000468796.1 hypothetical protein -
  MPG62_RS03270 (MPG62_03270) - 683677..684318 (-) 642 WP_245099915.1 ATP-binding cassette domain-containing protein -
  MPG62_RS03275 (MPG62_03275) - 684320..685981 (-) 1662 WP_245099916.1 ABC transporter permease/substrate-binding protein -
  MPG62_RS03280 (MPG62_03280) - 686115..686552 (-) 438 WP_001031792.1 hypothetical protein -
  MPG62_RS03285 (MPG62_03285) motB 686556..687323 (-) 768 WP_001085319.1 flagellar motor protein MotB -

Sequence

Protein


Download         Length: 594 a.a.        Molecular weight: 68797.10 Da        Isoelectric Point: 9.7468

>NTDB_id=666417 MPG62_RS03255 WP_245099911.1 681248..683032(-) (uvrC) [Helicobacter pylori strain Hpfe106]
MADLLSSLKNLSHSSGVYQYFDKNRQLLYIGKAKNLKKRIKSYFSVHNNEITPNHRASLRIQIMVKQIAFLETILVENEQ
DALILENSLIKQLKPKYNILLRDDKTYPYIYMDFSTDFPIPLITRKILKQPGVKYFGPFTSGAKDILDSLYELLPLVQKK
NCIKDKKACMFYQIERCKAPCENKITKEEYLKITKECLEMIENKDKLIKKLELKMERLSNNLRFEEALIYRDRIAKIQKI
APFTCMDLAKLYDLDIFAFYSGSNKAVLVKMFMRGGKIISSAFEKIHSLNGFDTDEAMKQAIINHYQSHLPLMPEQILLN
ACSNETLKELQEFISHKYSKKIALSIPKKGDKLALIEIAMKNAQEIFSQEKTSNEDLILEEARSLFQLECMPYRVEIFDT
SHHANSQCVGGMVVYENHEFQKNSYRRYHLKGSNEYTQMSELLTRRALDFAKEPPPNLWVIDGGRAQLNIALEILKSSGS
FVEVIAISKEKRDSKAYRSKGGAKDIIHTANDTFKLLPSDKRLQWVQKLRDESHRYAINFHRSTKLKNMKQIVLLKEKGI
GEASVKKLLDYFGSFEAIEKASEQEKNAVLKKRI

Nucleotide


Download         Length: 1785 bp        

>NTDB_id=666417 MPG62_RS03255 WP_245099911.1 681248..683032(-) (uvrC) [Helicobacter pylori strain Hpfe106]
ATGGCTGATTTGTTGTCCAGTTTGAAAAATCTTTCTCATAGCAGTGGCGTGTATCAATATTTTGATAAAAACCGCCAATT
ACTCTATATCGGTAAGGCAAAAAATTTAAAAAAGCGCATCAAAAGCTATTTTTCTGTCCACAATAATGAAATCACGCCCA
ATCATCGCGCAAGCTTACGAATCCAAATAATGGTCAAACAGATCGCTTTTTTAGAAACCATTTTAGTGGAAAACGAACAA
GACGCTTTGATTTTAGAAAATTCTTTAATCAAGCAGCTCAAACCCAAATACAACATTCTTTTAAGAGACGATAAAACTTA
CCCCTATATTTATATGGATTTTTCCACTGATTTCCCCATCCCTTTAATCACACGAAAAATTTTAAAACAGCCTGGCGTTA
AATATTTTGGCCCTTTTACGAGTGGGGCTAAAGATATTTTAGACAGCTTGTATGAATTGCTCCCGTTAGTTCAAAAGAAA
AATTGCATCAAGGATAAAAAGGCATGCATGTTTTATCAAATAGAGCGTTGTAAAGCCCCATGCGAGAATAAAATCACCAA
AGAAGAGTATTTGAAAATCACTAAAGAATGTTTAGAAATGATTGAAAATAAAGACAAACTCATCAAAAAGCTTGAATTAA
AAATGGAGCGCCTTTCTAATAACTTGCGTTTTGAAGAAGCCCTCATTTATAGGGATAGGATTGCAAAAATCCAAAAAATC
GCCCCTTTCACTTGCATGGATTTGGCCAAACTCTATGATTTGGATATTTTTGCTTTTTATAGTGGGAGCAATAAGGCGGT
GTTAGTGAAAATGTTTATGCGTGGGGGTAAAATCATTTCTTCAGCGTTTGAAAAAATCCACTCTCTTAATGGGTTTGACA
CTGATGAAGCGATGAAACAAGCTATTATCAATCATTACCAATCGCATTTGCCTTTGATGCCTGAACAAATCTTATTGAAC
GCTTGTTCTAATGAAACGCTTAAAGAATTGCAAGAATTTATCTCTCATAAATACTCTAAAAAAATCGCTCTTAGTATTCC
TAAAAAAGGCGATAAACTCGCTTTAATAGAAATCGCTATGAAAAACGCTCAAGAGATTTTTAGCCAAGAAAAAACCTCTA
ATGAAGATCTGATTTTAGAAGAAGCGCGATCGCTCTTTCAATTAGAGTGCATGCCTTATAGGGTGGAAATCTTTGACACA
AGCCACCATGCCAACAGCCAATGCGTGGGGGGAATGGTCGTGTATGAAAATCATGAATTTCAAAAAAACTCCTATCGGCG
CTACCATTTAAAAGGCTCTAATGAATACACTCAAATGAGCGAATTGCTCACCAGAAGGGCTTTAGATTTTGCCAAAGAGC
CGCCGCCTAATTTGTGGGTGATCGATGGAGGGAGAGCGCAATTAAACATCGCTTTAGAAATTTTAAAAAGCAGCGGGAGT
TTTGTAGAAGTGATCGCTATTTCTAAAGAAAAAAGGGATTCTAAAGCTTATCGCTCTAAAGGAGGCGCTAAAGACATTAT
CCACACCGCTAACGATACTTTTAAATTGCTCCCTAGCGACAAGCGCTTGCAGTGGGTGCAAAAATTGCGCGATGAAAGCC
ACCGGTATGCGATAAACTTCCATAGATCCACTAAACTTAAAAACATGAAACAAATCGTGCTTTTAAAAGAAAAGGGTATA
GGAGAAGCTAGCGTGAAAAAATTGTTGGATTATTTTGGGAGTTTTGAAGCGATAGAAAAAGCGAGCGAGCAGGAAAAAAA
CGCCGTTTTAAAAAAACGGATTTAA

Domains

Predicted by InterproScan.

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(385-538)

GIY-YIG catalytic domain (GIY-YIG)

(15-98)

UvrB/uvrC motif (UVR)

(205-239)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

96.465

100

0.965