Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB8   Type   Machinery gene
Locus tag   MPG33_RS00690 Genome accession   NZ_CP094070
Coordinates   148622..149365 (+) Length   247 a.a.
NCBI ID   WP_156584896.1    Uniprot ID   A0A7K1NZY1
Organism   Helicobacter pylori strain Hpfe107     
Function   transformation-associated type IV transport system (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 143622..154365
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MPG33_RS00665 (MPG33_00665) panD 145772..146122 (+) 351 WP_180478221.1 aspartate 1-decarboxylase -
  MPG33_RS00670 (MPG33_00670) - 146133..146426 (+) 294 WP_000347917.1 YbaB/EbfC family nucleoid-associated protein -
  MPG33_RS00675 (MPG33_00675) - 146426..147421 (+) 996 WP_245063234.1 PDZ domain-containing protein -
  MPG33_RS00680 (MPG33_00680) comB6 147429..148484 (+) 1056 WP_154450108.1 P-type conjugative transfer protein TrbL Machinery gene
  MPG33_RS00685 (MPG33_00685) comB7 148500..148625 (+) 126 WP_024117273.1 hypothetical protein Machinery gene
  MPG33_RS00690 (MPG33_00690) comB8 148622..149365 (+) 744 WP_156584896.1 virB8 family protein Machinery gene
  MPG33_RS00695 (MPG33_00695) comB9 149365..150336 (+) 972 WP_245062828.1 TrbG/VirB9 family P-type conjugative transfer protein Machinery gene
  MPG33_RS00700 (MPG33_00700) comB10 150329..151465 (+) 1137 WP_245062830.1 DNA type IV secretion system protein ComB10 Machinery gene
  MPG33_RS00705 (MPG33_00705) - 151531..152943 (+) 1413 WP_245062832.1 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase -
  MPG33_RS00710 (MPG33_00710) gmd 152957..154102 (+) 1146 WP_245062834.1 GDP-mannose 4,6-dehydratase -

Sequence

Protein


Download         Length: 247 a.a.        Molecular weight: 28671.91 Da        Isoelectric Point: 8.9546

>NTDB_id=666394 MPG33_RS00690 WP_156584896.1 148622..149365(+) (comB8) [Helicobacter pylori strain Hpfe107]
MKEKPFNSEQLIYLEELLSHQEKHLENKLSGFSVSDLDMQSVFRLERNRLKIAYKLLGLMSFIALVLAIVLISVLPLQKT
EHHFVDFLNQDKHYAIIQRADKSISSNEALARSLIGAYVLNRESINRIDDKSRYELVRLQSSSKVWQRFEDLIKTQNSIY
AQSHLEREVHIVNIAIYQQDNNPIASVSIAAKLMNENKLVYEKRYKIVLSYLFDTPDFDYASMPKNPTGFKITRYSITEI
APTNRGD

Nucleotide


Download         Length: 744 bp        

>NTDB_id=666394 MPG33_RS00690 WP_156584896.1 148622..149365(+) (comB8) [Helicobacter pylori strain Hpfe107]
ATGAAAGAAAAGCCTTTCAATAGCGAGCAATTGATCTATTTAGAAGAGCTTTTAAGCCACCAAGAAAAGCATTTAGAAAA
CAAGCTTTCTGGTTTTTCGGTGAGTGATTTGGACATGCAAAGCGTGTTCAGACTAGAGAGGAACCGCTTGAAAATCGCTT
ATAAACTCTTAGGCTTGATGAGTTTTATCGCTCTTGTTTTAGCGATCGTGTTAATCAGTGTTTTACCCTTACAAAAAACC
GAACACCATTTCGTGGATTTTTTAAACCAAGACAAGCATTACGCTATTATCCAAAGAGCGGATAAAAGCATTTCCAGTAA
TGAAGCGTTGGCTCGTTCGCTCATTGGGGCGTATGTGTTAAACCGAGAGAGCATTAACCGTATTGACGATAAATCGCGCT
ATGAATTGGTGCGTTTGCAAAGCAGCTCTAAAGTGTGGCAACGCTTTGAAGATTTGATCAAAACGCAAAACAGCATTTAT
GCGCAAAGCCATTTGGAAAGAGAAGTCCATATCGTCAATATTGCGATCTATCAGCAAGACAATAACCCCATTGCGAGCGT
TTCTATTGCAGCTAAACTCATGAATGAAAACAAGTTGGTATATGAAAAGCGTTATAAAATCGTGCTGAGTTATTTGTTTG
ACACCCCAGATTTTGATTACGCTTCCATGCCTAAAAACCCTACCGGCTTTAAAATCACTCGCTACAGCATCACTGAAATC
GCGCCGACTAATAGGGGCGATTGA

Domains

Predicted by InterproScan.

VirB8 protein (VirB8)

(38-239)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7K1NZY1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB8 Helicobacter pylori P1

97.976

100

0.98