Detailed information NTG0666385

Bioinformatically predicted

Overview

• Name: disA
• Type: Machinery gene
• Locus tag: OH827_RS14590
• Genome accession: NZ_CP108779
• Coordinates: 3329862..3330986 (+)
• Length: 374 a.a.
• NCBI ID: WP_026171409.1
• Uniprot ID: A0ABY6PU31
• Organism: Streptomyces sp. NBC_00891
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 3324862..3335986

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
OH827_RS14575 (OH827_14555)	-	3325509..3326291 (+)	783	WP_405884917.1	hypothetical protein	-
OH827_RS14580 (OH827_14560)	-	3326305..3328167 (-)	1863	WP_330452658.1	hypothetical protein	-
OH827_RS14585 (OH827_14565)	radA/sms	3328303..3329715 (+)	1413	WP_018520499.1	DNA repair protein RadA	Machinery gene
OH827_RS14590 (OH827_14570)	disA	3329862..3330986 (+)	1125	WP_026171409.1	DNA integrity scanning diadenylate cyclase DisA	Machinery gene
OH827_RS14595 (OH827_14575)	-	3331036..3331806 (-)	771	WP_330455191.1	hypothetical protein	-
OH827_RS14600 (OH827_14580)	-	3332140..3333042 (+)	903	WP_093708251.1	A/G-specific adenine glycosylase	-
OH827_RS14605 (OH827_14585)	-	3333359..3333907 (+)	549	WP_018520495.1	SigE family RNA polymerase sigma factor	-
OH827_RS14610 (OH827_14590)	-	3333895..3334614 (+)	720	WP_330452659.1	hypothetical protein	-
OH827_RS14615 (OH827_14595)	cseB	3334625..3335329 (+)	705	WP_164644028.1	two-component system response regulator CseB	-

Sequence

Protein

• Length: 374 a.a.
• Molecular weight: 40422.37 Da
• Isoelectric Point: 5.0161

>NTDB_id=666385 OH827_RS14590 WP_026171409.1 3329862..3330986(+) (disA) [Streptomyces sp. NBC_00891]
MAASDRAASPGKSGQTTGNEALMRASLSAVAPGMALRDGLERILRGNTGGLIVLGMDKTVESMCTGGFVLDVEFTATRLR
ELAKLDGALILDKDMTKILRAGVQLVPDASIPTEETGTRHRTADRVSKQCNFPVVSVSQSMRLIALYVNGERRVLEESAA
ILSRANQALATLERYKLRLDEVAGTLSALEIEDLVTVRDVTAVAQRLEMVRRIATEIAEYVVELGTDGRLLSLQLDELIA
GVEPERELVVRDYVPEPTAKRSRTVAEALTELDSLTHTELLELPVVARALGYSGSPETLDSAVSPRGFRLLAKVPRLPGA
IIDRLVEHFGGLQKLLAASVDDLQTVDGVGEARARSVREGLSRLAESSILERYV

Nucleotide

• Length: 1125 bp

>NTDB_id=666385 OH827_RS14590 WP_026171409.1 3329862..3330986(+) (disA) [Streptomyces sp. NBC_00891]
GTGGCAGCCAGCGACCGGGCAGCATCGCCCGGAAAGTCCGGCCAAACCACCGGTAACGAGGCGCTCATGCGCGCCTCGTT
GAGCGCCGTCGCGCCCGGTATGGCCCTGCGGGACGGCCTGGAGCGCATTCTCCGCGGCAACACCGGGGGTCTGATCGTGC
TCGGCATGGACAAGACCGTCGAGTCGATGTGTACCGGCGGCTTCGTGCTGGACGTGGAGTTCACCGCGACCCGGCTGCGG
GAGCTCGCCAAGCTCGACGGGGCTCTGATTCTCGACAAGGACATGACGAAGATCCTGCGGGCCGGCGTGCAGCTGGTCCC
GGACGCGTCGATCCCCACCGAGGAGACCGGCACCCGGCACCGCACGGCGGACCGGGTCTCCAAGCAGTGCAATTTCCCGG
TCGTCTCGGTCTCCCAGTCGATGCGCCTGATCGCGCTGTACGTGAACGGGGAGCGCCGGGTCCTGGAGGAGTCGGCGGCG
ATCCTGTCCCGCGCCAACCAGGCGCTCGCGACGCTGGAGCGGTACAAGCTGCGGCTCGACGAGGTCGCCGGGACGCTCTC
CGCGCTGGAGATCGAGGACCTGGTGACCGTCCGGGACGTGACGGCGGTGGCCCAGCGCCTGGAGATGGTCCGCCGGATCG
CGACGGAGATCGCGGAGTACGTGGTGGAGCTCGGCACCGACGGGCGGCTGCTGTCGCTCCAGCTGGACGAGCTGATCGCG
GGCGTGGAGCCGGAGCGCGAGCTGGTCGTGCGGGACTATGTGCCGGAGCCGACCGCGAAGCGTTCGCGCACGGTGGCGGA
GGCGCTGACCGAGCTGGACTCGCTGACCCACACGGAGCTGCTCGAACTCCCGGTGGTGGCGAGGGCGCTGGGCTACAGCG
GTTCGCCCGAGACGCTGGACTCGGCGGTGTCGCCGCGCGGTTTCCGGCTGCTGGCGAAGGTGCCGCGGCTGCCCGGCGCG
ATCATCGACCGGCTCGTGGAGCACTTCGGCGGTCTGCAGAAGCTGCTCGCGGCGAGCGTGGACGACCTCCAGACGGTGGA
CGGGGTCGGCGAGGCCCGCGCGCGCAGCGTGCGCGAGGGCCTGTCCCGGCTGGCCGAGTCGTCGATCCTCGAACGGTACG
TGTAG

Domains

Predicted by InterProScan.

• Helix-hairpin-helix motif (HHH_2) (324-359)

• DisA bacterial checkpoint controller nucleotide-binding (DAC) (38-151)

• DisA bacterial checkpoint controller linker region (DisA-linker) (155-297)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
disA	Bacillus subtilis subsp. subtilis str. 168	44.598	96.524	0.43