Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB4   Type   Machinery gene
Locus tag   MPG12_RS07345 Genome accession   NZ_CP094062
Coordinates   1541563..1543926 (-) Length   787 a.a.
NCBI ID   WP_245045780.1    Uniprot ID   -
Organism   Helicobacter pylori strain Hpfe118     
Function   transformation-associated type IV transport system (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1536563..1548926
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MPG12_RS07320 (MPG12_07320) lpxE 1537080..1537613 (+) 534 WP_245046565.1 lipid A 1-phosphatase LpxE -
  MPG12_RS07325 (MPG12_07325) nspC 1537623..1538840 (-) 1218 WP_245045778.1 carboxynorspermidine decarboxylase -
  MPG12_RS07330 (MPG12_07330) cheV1 1538837..1539802 (-) 966 WP_220995778.1 chemotaxis protein CheV1 -
  MPG12_RS07335 (MPG12_07335) - 1539903..1541243 (-) 1341 WP_172416898.1 hypothetical protein -
  MPG12_RS07345 (MPG12_07345) comB4 1541563..1543926 (-) 2364 WP_245045780.1 VirB4 family type IV secretion/conjugal transfer ATPase Machinery gene
  MPG12_RS07350 (MPG12_07350) comB3 1543928..1544191 (-) 264 WP_000584971.1 hypothetical protein Machinery gene
  MPG12_RS07355 (MPG12_07355) comB2 1544191..1544472 (-) 282 WP_001272686.1 TrbC/VirB2 family protein Machinery gene
  MPG12_RS07360 (MPG12_07360) - 1544617..1545444 (-) 828 WP_048944995.1 DUF5718 family protein -
  MPG12_RS07365 (MPG12_07365) - 1545534..1546586 (-) 1053 WP_021301516.1 MnmA/TRMU family protein -
  MPG12_RS07370 (MPG12_07370) dnaG 1546583..1548262 (-) 1680 WP_245045781.1 DNA primase -
  MPG12_RS07375 (MPG12_07375) groES 1548548..1548904 (+) 357 WP_000671953.1 co-chaperone GroES -

Sequence

Protein


Download         Length: 787 a.a.        Molecular weight: 90121.83 Da        Isoelectric Point: 9.0323

>NTDB_id=666276 MPG12_RS07345 WP_245045780.1 1541563..1543926(-) (comB4) [Helicobacter pylori strain Hpfe118]
MLEKLLSAVKQKVSNYFLGVLPKSYSMSEENNILGLYDEHFLLTKNENLVGILRLEGVSYTHLSTEQLQDLFTERQMALD
SLEKVVARLVVKRRKIDHQQNIQTNSKYLQAILNQFENKEVYENQYFLVLESAHSLQGVLEHKKKSLMHANRENFKDILS
YKAHFLQETLKSLEIQLKNYAPKLLSSKEVLNFYAEYINGFDLPLKPLVGGYLSDSYIASSITFEKDYFIQESFNQKTYN
RLIGIKAYESERITSIAIGALLYQETPLDIIFSIEPMSVNKTLSFLKERAKFSMSNLVKNELLEYQELVKTKRLSMQKFA
LNILIKAPSLEDLDTQTSLVLGLLFKENLVGVIETFGLKGGYFSFFPERIHLNHRLRFLTSKALACLMVFERQNLGFKAN
SWGNSPLSVFKNLDYSPFLFNFHNQEVSHNNAKEIARVNGHTLIIGATGSGKSTLISFLMMSALKYQNMRLLAFDRMQGL
YSFTKFFKGHYHDGKSFSINPFCLEPNLQNLEFLQSFFLSMFDLAPSRDKEALEDMNAILSAIKSLYETLCPKAFSLLDF
KETLKRTSSNQLGLSLEPYLNNPLFNALNDAFNSSAFLNVINLDAITQNPKDLGLLAYYLFYKILEESRKNDSGFLVFLD
EFKSYVENDLLNAKINALITQARKANGVVVLALQDIYQLSGVKNAHSFLSNMGTLILYPQKNARELKHHFNVPLSETEIS
FLENTPLYARQVLVKNLGNGSSNMIDVSLEGLGRYLKIFNSDSSHVNKVKALQKDYPKEWREKLLKS

Nucleotide


Download         Length: 2364 bp        

>NTDB_id=666276 MPG12_RS07345 WP_245045780.1 1541563..1543926(-) (comB4) [Helicobacter pylori strain Hpfe118]
ATGTTAGAAAAGCTTTTGAGTGCTGTCAAACAAAAAGTTTCAAACTATTTTTTAGGGGTTTTGCCTAAAAGCTATTCTAT
GAGCGAAGAAAACAACATTTTAGGCTTGTATGATGAGCATTTCTTGCTCACTAAAAACGAAAACTTAGTGGGAATTCTCC
GTTTAGAGGGGGTGAGTTACACCCATTTAAGCACAGAGCAATTGCAAGATCTCTTCACCGAGCGCCAAATGGCGTTGGAT
TCTTTAGAAAAAGTCGTGGCACGCCTTGTGGTTAAAAGGCGTAAAATTGATCACCAACAAAACATTCAAACCAATTCCAA
ATACTTGCAAGCGATTTTGAATCAATTTGAAAATAAAGAAGTGTATGAAAATCAGTATTTTTTAGTTTTAGAAAGCGCGC
ATTCTTTACAAGGCGTTTTAGAGCATAAGAAAAAATCTCTCATGCATGCCAATAGGGAAAATTTTAAGGATATTCTCTCT
TATAAAGCGCATTTTTTGCAAGAAACTTTAAAAAGCTTAGAAATCCAGCTCAAAAACTACGCCCCCAAACTCTTAAGCTC
CAAAGAGGTTTTGAATTTTTATGCGGAATACATTAACGGATTTGATCTCCCTTTAAAGCCCCTAGTAGGAGGGTATTTGA
GCGACAGCTATATCGCTAGTTCTATCACTTTTGAAAAAGATTATTTCATTCAAGAGAGCTTTAATCAAAAAACCTATAAC
CGCTTGATTGGCATTAAAGCTTATGAGAGCGAGCGCATCACTTCTATAGCGATCGGAGCACTTTTATACCAAGAAACGCC
TTTAGACATTATCTTTTCTATAGAGCCTATGAGCGTCAATAAAACGCTGAGTTTTTTAAAAGAAAGGGCCAAATTTAGCA
TGTCCAATCTCGTTAAAAACGAGCTGCTAGAATACCAAGAACTAGTCAAAACCAAACGCCTATCCATGCAAAAATTTGCC
CTAAACATTCTTATCAAAGCCCCTAGTTTAGAGGATTTAGACACTCAAACAAGCTTAGTTTTAGGGCTTTTATTTAAAGA
AAACTTAGTGGGCGTTATAGAAACTTTTGGCTTGAAGGGGGGGTATTTTTCCTTTTTCCCTGAACGCATCCACTTAAACC
ACCGCTTGCGTTTTTTAACCTCTAAAGCCTTAGCGTGTTTAATGGTGTTTGAAAGGCAAAATTTAGGTTTTAAGGCTAAT
TCATGGGGGAATAGCCCTTTGAGCGTGTTTAAAAATTTGGATTATTCCCCCTTTTTATTCAATTTCCACAACCAAGAAGT
GAGCCACAACAACGCTAAAGAAATCGCCAGAGTGAATGGGCATACTCTAATCATAGGGGCTACCGGGAGCGGTAAAAGCA
CGCTGATTAGTTTTTTAATGATGAGCGCTTTGAAATACCAAAACATGCGCCTTTTAGCATTTGACAGGATGCAAGGGCTG
TATTCTTTCACAAAATTTTTTAAAGGGCATTACCATGACGGCAAATCTTTTAGCATCAACCCCTTTTGTTTAGAACCTAA
TTTGCAGAATTTAGAATTTTTGCAATCCTTCTTTTTGAGCATGTTTGATCTTGCCCCTTCAAGGGATAAAGAAGCCTTAG
AAGACATGAATGCGATTTTGAGTGCGATTAAGAGCCTTTATGAGACTTTATGCCCTAAAGCTTTTAGTTTGCTAGATTTT
AAAGAAACGCTTAAAAGAACCTCATCTAACCAATTGGGCTTGAGTTTAGAGCCGTATTTGAATAACCCCCTTTTTAACGC
CTTGAATGACGCATTCAACTCCAGCGCTTTTTTAAATGTGATAAACCTAGATGCCATCACCCAAAACCCTAAAGACTTAG
GGCTTTTAGCCTATTATTTGTTTTATAAAATCTTAGAAGAATCCAGGAAAAACGACAGCGGTTTTTTGGTTTTTTTAGAC
GAGTTTAAATCCTATGTGGAAAACGATTTATTGAACGCTAAAATTAACGCTTTAATCACGCAAGCCAGAAAGGCTAATGG
CGTGGTGGTGTTGGCTTTGCAAGATATTTACCAATTAAGCGGGGTTAAAAACGCCCATAGTTTTTTAAGCAACATGGGGA
CTCTTATTTTGTATCCGCAAAAAAACGCTAGGGAGTTGAAACACCACTTCAATGTGCCTTTGAGCGAAACTGAAATTTCT
TTTTTAGAAAACACCCCTTTGTATGCTAGGCAGGTTTTAGTCAAAAATCTGGGTAATGGGAGTTCTAACATGATTGATGT
GAGTTTGGAGGGTTTGGGGCGTTATTTGAAAATCTTTAATTCAGACTCTAGCCATGTGAATAAAGTGAAAGCGTTACAAA
AAGACTACCCTAAAGAGTGGCGTGAGAAACTTTTGAAGAGCTAG

Domains

Predicted by InterproScan.

FtsK/SpoIIIE family (FtsK_SpoIIIE)

(426-466)

CagE, TrbE, VirB family, component of type IV transporter system (CagE_TrbE_VirB)

(176-375)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB4 Helicobacter pylori 26695

97.332

100

0.973