Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   MPG58_RS04585 Genome accession   NZ_CP094061
Coordinates   976333..978117 (+) Length   594 a.a.
NCBI ID   WP_245011445.1    Uniprot ID   -
Organism   Helicobacter pylori strain Hpfe120     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 971333..983117
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MPG58_RS04555 (MPG58_04555) motB 971995..972762 (+) 768 WP_001085304.1 flagellar motor protein MotB -
  MPG58_RS04560 (MPG58_04560) - 972766..973203 (+) 438 WP_001031792.1 hypothetical protein -
  MPG58_RS04565 (MPG58_04565) - 973382..975043 (+) 1662 WP_245011442.1 ABC transporter permease/substrate-binding protein -
  MPG58_RS04570 (MPG58_04570) - 975047..975688 (+) 642 WP_245011443.1 ABC transporter ATP-binding protein -
  MPG58_RS04575 (MPG58_04575) - 975700..975879 (-) 180 WP_000468796.1 hypothetical protein -
  MPG58_RS04580 (MPG58_04580) - 975871..976332 (+) 462 WP_245011444.1 hypothetical protein -
  MPG58_RS04585 (MPG58_04585) uvrC 976333..978117 (+) 1785 WP_245011445.1 excinuclease ABC subunit UvrC Machinery gene
  MPG58_RS04590 (MPG58_04590) - 978128..979393 (+) 1266 WP_121297005.1 homoserine dehydrogenase -
  MPG58_RS04595 (MPG58_04595) - 979394..979738 (+) 345 WP_033587184.1 YraN family protein -
  MPG58_RS04600 (MPG58_04600) trxA 979828..980148 (+) 321 WP_000020200.1 thioredoxin -
  MPG58_RS04605 (MPG58_04605) trxB 980154..981089 (+) 936 WP_245011446.1 thioredoxin-disulfide reductase -
  MPG58_RS04610 (MPG58_04610) - 981257..982078 (+) 822 WP_245011447.1 glycosyltransferase family 25 protein -
  MPG58_RS04615 (MPG58_04615) - 982283..982531 (-) 249 WP_000790557.1 RNA-binding protein -

Sequence

Protein


Download         Length: 594 a.a.        Molecular weight: 68789.01 Da        Isoelectric Point: 9.6675

>NTDB_id=666246 MPG58_RS04585 WP_245011445.1 976333..978117(+) (uvrC) [Helicobacter pylori strain Hpfe120]
MADLLSSLKNLSHSSGVYQYFDKNRQLLYIGKAKNLKKRIKSYFSVRNNEITPNHRASLRIQMMVKQIAFLETILVENEQ
DALILENSLIKQLKPKYNILLRDDKTYPYIYMDFSTDFPIPLITRKILKQPGVKYFGPFTSGAKDILDSLYELLPLVQKK
NCIKDKKACMFYQIERCKAPCENKITKEEYLKIAKECLEMIENKDKLIKELELKMERLSNNLRFEEALIYRDRIAKIQKI
ASFTCMDLAKLYDLDIFAFYSGSHKAVLVKMFMRGGKIISSAFEKIHSLNGFDTDEAMKQAIINHYQSHLPLMPEQILLN
ACSNETLKELQDFISHQYSKKIALSIPKKGDKLALIEIAMKNAQEIFSQEKTSNEDLILEEAQSLFKLECMPYRVEIFDA
SHHANSQCVGGMVVYENHEFQKNSYRRYHLKGSNEYTQMSELLTRRALDFNKEPPPNLWVIDGGRVQLNIALEILKSSGS
FVEVIAISKEKRDSKAYRSKGGAKDIIHTANDTFKLLPSDKRLQWVQKLRDESHRYAINFHRSTKLKNMKQIALLKEKGI
GEASVKKLLDYFGSFEAIEKASEQEKNAVLKKRI

Nucleotide


Download         Length: 1785 bp        

>NTDB_id=666246 MPG58_RS04585 WP_245011445.1 976333..978117(+) (uvrC) [Helicobacter pylori strain Hpfe120]
ATGGCTGATTTATTGTCCAGTTTGAAAAACCTTTCTCATAGCAGTGGCGTGTATCAATATTTTGATAAAAACCGCCAATT
ACTCTATATCGGTAAGGCGAAAAATTTAAAAAAGCGCATCAAAAGTTATTTTTCTGTCCGCAATAATGAAATCACGCCCA
ATCATCGTGCAAGCTTACGCATCCAAATGATGGTCAAACAGATCGCTTTTTTAGAAACCATTTTAGTGGAAAATGAGCAA
GACGCTTTGATTTTAGAAAACTCTTTAATCAAGCAGCTCAAACCCAAATACAACATTCTTTTAAGAGATGATAAAACTTA
CCCTTATATTTACATGGATTTTTCCACTGATTTCCCTATCCCTTTAATCACACGAAAAATTTTAAAACAGCCTGGCGTTA
AATATTTTGGCCCTTTTACGAGCGGGGCTAAGGATATTTTAGACAGCTTGTATGAATTGCTCCCGTTAGTTCAAAAGAAA
AATTGCATCAAGGATAAAAAGGCATGCATGTTTTATCAAATAGAGCGTTGTAAAGCCCCATGCGAGAATAAAATCACCAA
AGAAGAGTATTTAAAAATCGCTAAAGAATGTTTAGAAATGATTGAAAATAAAGACAAACTCATCAAAGAGCTTGAATTAA
AAATGGAGCGCCTTTCTAATAACTTGCGTTTTGAAGAAGCCCTCATTTATAGGGACAGGATTGCAAAAATCCAAAAAATC
GCCTCCTTTACTTGCATGGATTTAGCCAAGCTCTATGATTTGGATATTTTTGCTTTTTATAGTGGGAGCCATAAGGCGGT
GTTAGTGAAAATGTTTATGCGTGGGGGTAAAATCATTTCTTCAGCGTTTGAAAAAATCCACTCTCTTAATGGGTTTGACA
CTGATGAAGCGATGAAACAAGCCATTATCAATCATTACCAATCGCATTTGCCTTTAATGCCAGAACAAATCTTATTGAAC
GCTTGCTCTAATGAAACGCTTAAAGAATTGCAAGATTTTATCTCTCATCAATACTCTAAAAAAATCGCTCTTAGCATTCC
TAAAAAAGGCGATAAACTCGCTTTAATAGAAATCGCTATGAAAAACGCTCAAGAGATTTTTAGCCAAGAAAAAACCTCTA
ATGAAGATCTGATTTTAGAAGAAGCGCAATCGCTTTTTAAATTAGAGTGCATGCCTTATAGGGTGGAAATCTTTGATGCA
AGCCACCATGCCAACAGCCAATGCGTGGGGGGAATGGTCGTGTATGAAAATCATGAATTTCAAAAAAACTCCTATCGGCG
CTACCATTTAAAAGGCTCTAACGAATACACTCAAATGAGCGAATTGCTCACCAGAAGGGCTTTAGATTTTAATAAAGAGC
CACCGCCTAATTTGTGGGTGATCGATGGAGGGAGGGTGCAATTAAACATCGCTTTAGAAATTTTAAAAAGCAGCGGGAGT
TTTGTAGAAGTGATCGCTATTTCTAAAGAAAAAAGGGATTCTAAAGCTTATCGCTCTAAAGGAGGCGCTAAAGACATCAT
CCACACCGCTAACGATACTTTTAAATTGCTCCCTAGCGACAAGCGCTTGCAGTGGGTTCAAAAATTGCGCGATGAAAGCC
ACCGGTATGCGATAAACTTCCATAGATCCACTAAACTTAAAAACATGAAACAAATCGCTCTTTTAAAAGAAAAAGGCATA
GGAGAAGCTAGCGTGAAAAAATTATTGGATTATTTTGGGAGTTTTGAAGCGATAGAAAAAGCGAGCGAGCAGGAAAAAAA
CGCTGTTTTAAAAAAACGAATCTAA

Domains

Predicted by InterproScan.

GIY-YIG catalytic domain (GIY-YIG)

(15-98)

UvrB/uvrC motif (UVR)

(205-239)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(384-538)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

96.465

100

0.965