Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   MPG08_RS04035 Genome accession   NZ_CP094058
Coordinates   860519..862303 (-) Length   594 a.a.
NCBI ID   WP_245041630.1    Uniprot ID   -
Organism   Helicobacter pylori strain Hpfe123     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 855519..867303
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MPG08_RS04005 (MPG08_04005) - 856113..856361 (+) 249 WP_000790557.1 RNA-binding protein -
  MPG08_RS04010 (MPG08_04010) - 856559..857380 (-) 822 WP_245041628.1 glycosyltransferase family 25 protein -
  MPG08_RS04015 (MPG08_04015) trxB 857548..858483 (-) 936 WP_245041629.1 thioredoxin-disulfide reductase -
  MPG08_RS04020 (MPG08_04020) trxA 858489..858809 (-) 321 WP_000020199.1 thioredoxin -
  MPG08_RS04025 (MPG08_04025) - 858898..859242 (-) 345 WP_001211650.1 YraN family protein -
  MPG08_RS04030 (MPG08_04030) - 859243..860508 (-) 1266 WP_050832912.1 homoserine dehydrogenase -
  MPG08_RS04035 (MPG08_04035) uvrC 860519..862303 (-) 1785 WP_245041630.1 excinuclease ABC subunit UvrC Machinery gene
  MPG08_RS04040 (MPG08_04040) - 862304..862765 (-) 462 WP_000437191.1 hypothetical protein -
  MPG08_RS04045 (MPG08_04045) - 862757..862936 (+) 180 WP_000468796.1 hypothetical protein -
  MPG08_RS04050 (MPG08_04050) - 862948..863589 (-) 642 WP_245041631.1 ATP-binding cassette domain-containing protein -
  MPG08_RS04055 (MPG08_04055) - 863591..865252 (-) 1662 WP_245041632.1 ABC transporter permease/substrate-binding protein -
  MPG08_RS04060 (MPG08_04060) - 865433..865870 (-) 438 WP_001031792.1 hypothetical protein -
  MPG08_RS04065 (MPG08_04065) motB 865874..866641 (-) 768 WP_001085311.1 flagellar motor protein MotB -

Sequence

Protein


Download         Length: 594 a.a.        Molecular weight: 68829.12 Da        Isoelectric Point: 9.7468

>NTDB_id=666204 MPG08_RS04035 WP_245041630.1 860519..862303(-) (uvrC) [Helicobacter pylori strain Hpfe123]
MADLLSSLKNLSHSSGVYQYFDKNRQLLYIGKAKNLKKRIKSYFSIHNNKITPNHRASLRIQMMVKQIAFLETILVENEQ
DALILENSLIKQLKPKYNILLRDDKTYPYIYMDFSTDFPIPLITRKILKQPGVKYFGPFTSGAKDILDSLYELLPLVQKK
NCIKDKKACMFYQIERCKAPCENKITKEEYSKIAKECLEMIENKDKLIKELELKMERLSNNLRFEEALIYRDRIAKIQKI
APFTCMDLAKLYDLDIFAFYSGSHKAVLVKMFMRGGKIISSAFEKIHSLNGFDTDEAMKQAIINHYQSHLPLMPEQILLN
ACSNETLKELQEFISHKYSKKIAISIPKKGDKLALIEIAMKNAQEIFSQEKTSNEDLILEEARSLFQLECMPYRVEIFDT
SHHANSQCVGGMVVYENHEFQKNSYRRYHLKGSNEYTQMSELLTRRALDFAKEPPPNLWVIDGGRVQLNIALEILKSSGS
FVEVIAISKEKRDSKAYRSKGGTKDIIHTASDTFKLLPSDKRLQWVQKLRDESHRYAINFHRSTKLKNMKQIALLKEKGI
GETSVKKLLDYFGSFEAIEKASEQEKNAVLKKRI

Nucleotide


Download         Length: 1785 bp        

>NTDB_id=666204 MPG08_RS04035 WP_245041630.1 860519..862303(-) (uvrC) [Helicobacter pylori strain Hpfe123]
ATGGCTGATTTATTGTCAAGTTTGAAAAACCTTTCTCATAGCAGTGGCGTGTATCAATATTTTGATAAAAACCGCCAATT
ACTCTATATCGGTAAGGCGAAAAATTTAAAAAAGCGCATCAAAAGCTATTTTTCTATCCACAATAATAAAATCACGCCTA
ACCATCGCGCAAGCTTACGAATCCAAATGATGGTCAAACAGATCGCTTTTTTAGAAACCATTTTAGTGGAAAACGAGCAA
GACGCTTTGATTTTAGAAAACTCTTTAATCAAGCAGCTCAAGCCCAAATACAACATTCTTTTAAGAGATGATAAAACTTA
CCCTTATATTTACATGGATTTTTCCACTGATTTCCCTATCCCTTTAATCACACGAAAAATTTTAAAACAGCCTGGCGTTA
AATATTTTGGCCCTTTTACGAGTGGGGCTAAAGATATTTTAGACAGCTTGTATGAATTGCTCCCGTTAGTTCAAAAGAAA
AATTGCATCAAAGATAAAAAGGCATGCATGTTTTATCAAATAGAGCGTTGTAAAGCCCCATGCGAGAATAAAATCACCAA
AGAAGAGTATTCAAAAATCGCTAAAGAATGTTTAGAAATGATTGAAAATAAAGACAAACTCATCAAAGAGCTTGAATTAA
AAATGGAGCGCCTTTCTAATAACTTGCGTTTTGAAGAAGCCCTCATTTATAGGGATAGGATTGCAAAAATCCAAAAAATC
GCCCCTTTCACTTGCATGGATTTAGCCAAACTCTATGATTTGGATATTTTTGCTTTTTATAGTGGGAGCCATAAGGCGGT
GTTAGTGAAAATGTTTATGCGTGGGGGTAAAATCATTTCTTCAGCGTTTGAAAAAATCCACTCTCTTAATGGGTTTGACA
CTGATGAAGCGATGAAACAAGCTATTATCAATCATTACCAATCGCATTTGCCTTTAATGCCTGAACAGATTTTATTGAAC
GCTTGCTCTAATGAAACGCTTAAAGAATTGCAAGAATTTATCTCTCATAAATACTCTAAAAAAATCGCTATTAGTATTCC
TAAAAAAGGCGATAAGCTCGCTTTAATAGAAATCGCTATGAAAAACGCTCAAGAGATTTTTAGCCAAGAAAAAACCTCTA
ATGAAGATCTGATTTTAGAAGAAGCGCGATCGCTCTTTCAATTAGAGTGCATGCCTTATAGGGTGGAAATCTTTGACACA
AGCCACCATGCCAACAGCCAATGCGTGGGGGGAATGGTCGTGTATGAAAATCATGAATTTCAAAAAAACTCCTATCGGCG
CTACCATTTAAAAGGCTCTAACGAATACACTCAAATGAGCGAATTGCTCACCAGAAGGGCTTTAGATTTTGCCAAAGAGC
CACCGCCTAATTTGTGGGTGATCGATGGAGGGAGGGTGCAATTAAACATCGCTTTAGAAATTTTAAAAAGCAGCGGGAGT
TTTGTAGAAGTGATCGCTATTTCTAAAGAAAAAAGGGATTCTAAAGCTTATCGCTCTAAAGGGGGCACTAAAGACATTAT
CCACACCGCTAGCGATACTTTTAAATTGCTCCCTAGCGACAAACGCTTGCAGTGGGTGCAAAAATTGCGCGATGAAAGCC
ACCGGTATGCGATAAACTTCCATAGATCCACTAAACTTAAAAACATGAAACAAATCGCTCTTTTAAAAGAAAAGGGTATA
GGAGAAACCAGCGTGAAAAAATTATTGGATTATTTTGGGAGTTTTGAAGCGATAGAAAAAGCGAGCGAGCAGGAAAAAAA
CGCTGTTTTAAAAAAACGAATCTAA

Domains

Predicted by InterproScan.

GIY-YIG catalytic domain (GIY-YIG)

(15-98)

UvrB/uvrC motif (UVR)

(205-239)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(385-538)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

96.296

100

0.963