Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   MPF87_RS03200 Genome accession   NZ_CP094052
Coordinates   662913..664697 (-) Length   594 a.a.
NCBI ID   WP_245012969.1    Uniprot ID   -
Organism   Helicobacter pylori strain Hpfe126     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 657913..669697
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MPF87_RS03170 (MPF87_03170) - 658490..658738 (+) 249 WP_000790556.1 RNA-binding protein -
  MPF87_RS03175 (MPF87_03175) - 658954..659775 (-) 822 WP_245012967.1 glycosyltransferase family 25 protein -
  MPF87_RS03180 (MPF87_03180) trxB 659942..660877 (-) 936 WP_245012968.1 thioredoxin-disulfide reductase -
  MPF87_RS03185 (MPF87_03185) trxA 660883..661203 (-) 321 WP_000020199.1 thioredoxin -
  MPF87_RS03190 (MPF87_03190) - 661292..661636 (-) 345 WP_001211650.1 YraN family protein -
  MPF87_RS03195 (MPF87_03195) - 661637..662902 (-) 1266 WP_180605773.1 homoserine dehydrogenase -
  MPF87_RS03200 (MPF87_03200) uvrC 662913..664697 (-) 1785 WP_245012969.1 excinuclease ABC subunit UvrC Machinery gene
  MPF87_RS03205 (MPF87_03205) - 664698..665159 (-) 462 WP_245012970.1 hypothetical protein -
  MPF87_RS03210 (MPF87_03210) - 665151..665330 (+) 180 WP_000468796.1 hypothetical protein -
  MPF87_RS03215 (MPF87_03215) - 665342..665983 (-) 642 WP_245012971.1 ATP-binding cassette domain-containing protein -
  MPF87_RS03220 (MPF87_03220) - 665987..667648 (-) 1662 WP_245012972.1 ABC transporter permease/substrate-binding protein -
  MPF87_RS03225 (MPF87_03225) - 667833..668270 (-) 438 WP_245012973.1 hypothetical protein -
  MPF87_RS03230 (MPF87_03230) motB 668274..669041 (-) 768 WP_001085316.1 flagellar motor protein MotB -

Sequence

Protein


Download         Length: 594 a.a.        Molecular weight: 68787.04 Da        Isoelectric Point: 9.6734

>NTDB_id=666137 MPF87_RS03200 WP_245012969.1 662913..664697(-) (uvrC) [Helicobacter pylori strain Hpfe126]
MADLLSSLKNLSHSSGVYQYFDKNRQLLYIGKAKNLKKRIKSYFSVRNNEITPNHRASLRIQMMVKQIAFLETILVENEQ
DALILENSLIKQLKPKYNILLRDDKTYPYIYMDFSTDFPIPLITRKILKQPGVKYFGPFTSGAKDILDSLYELLPLVQKK
NCIKDKKACMFYQIERCKAPCENKITKEEYLKIAKECLEMIENKDKLIKELELKMERLSNNLRFEEALIYRDRIAKIQKI
APFTCMDLAKLYDLDIFAFYSGGNKAVLVKMFMRGGKIISSAFEKIHSLNGFDTDEAMKQAIINHYQSHLPLMPEQILLN
ACSNETLKELQDFISHQYSKKIALSIPKKGDKLALIEIAMKNAQEIFSQERISNEDLILEEVRSLFNLECMPYRVEIFDT
SHHANSQCVGGMVVYENHEFQKNSYRRYHLKGSNEYTQMSELLTRRALDFAKEPPPNLWVIDGGRAQLNIALEILKSSGS
FVEVIAISKEKRDSKAYRSKGGAKDIIHTANDTFKLLPSDKRLQWVQKLRDESHRYAINFHRSTKLKNMKQIALLKEKGI
GEASVKKLLDYFGSFEAIEKASEQEKNAVLKKRI

Nucleotide


Download         Length: 1785 bp        

>NTDB_id=666137 MPF87_RS03200 WP_245012969.1 662913..664697(-) (uvrC) [Helicobacter pylori strain Hpfe126]
ATGGCTGATTTATTGTCCAGTTTGAAAAATCTTTCTCATAGCAGTGGCGTGTATCAATATTTTGATAAAAACCGCCAATT
ACTCTATATCGGTAAGGCGAAAAATTTAAAAAAGCGTATCAAAAGCTATTTTTCTGTCCGTAATAATGAAATCACGCCCA
ATCATCGCGCAAGCTTACGAATCCAAATGATGGTCAAACAGATCGCTTTTTTAGAAACCATTTTAGTGGAAAACGAGCAA
GACGCTTTGATTTTAGAAAATTCTTTAATCAAGCAGCTCAAGCCCAAATACAACATTCTTTTAAGAGACGATAAAACTTA
CCCTTATATTTATATGGATTTTTCCACTGATTTCCCTATCCCTTTAATCACACGAAAAATTTTAAAACAGCCTGGCGTTA
AATATTTTGGCCCTTTTACGAGCGGGGCTAAAGATATTTTAGACAGCTTGTATGAATTGCTCCCGTTAGTTCAAAAGAAA
AATTGCATCAAAGATAAAAAAGCATGCATGTTTTATCAAATAGAGCGTTGTAAAGCCCCATGCGAGAATAAAATCACCAA
AGAAGAGTATTTAAAAATCGCTAAAGAATGTTTAGAAATGATTGAAAATAAAGACAAACTCATCAAAGAGCTTGAATTAA
AAATGGAGCGCCTTTCTAATAACTTGCGTTTTGAAGAAGCCCTCATTTATAGGGATAGGATTGCAAAAATCCAAAAAATC
GCCCCTTTCACTTGCATGGATTTAGCCAAACTCTATGATTTGGATATTTTTGCTTTTTATAGTGGGGGCAATAAGGCGGT
GTTAGTGAAAATGTTTATGCGTGGGGGTAAAATCATTTCTTCAGCGTTTGAAAAAATCCACTCTCTCAATGGGTTTGACA
CTGATGAAGCGATGAAACAAGCCATTATCAATCATTACCAATCGCATTTGCCTTTAATGCCTGAACAAATCTTATTGAAC
GCTTGCTCTAATGAAACGCTTAAAGAATTGCAAGATTTTATCTCTCATCAATACTCTAAAAAAATCGCTCTTAGCATTCC
TAAAAAAGGCGATAAGCTCGCTTTAATAGAAATCGCTATGAAAAATGCTCAAGAGATTTTTAGCCAAGAAAGAATCTCTA
ATGAAGATCTGATTTTAGAAGAAGTGCGATCGCTTTTTAATTTAGAGTGCATGCCTTATAGGGTGGAAATCTTTGACACA
AGCCACCATGCCAACAGCCAATGCGTGGGGGGAATGGTCGTGTATGAAAATCATGAATTTCAAAAAAACTCCTATCGGCG
CTACCATTTAAAAGGCTCTAATGAATACACTCAAATGAGCGAATTGCTCACCAGAAGGGCTTTAGATTTTGCCAAAGAGC
CACCGCCTAATTTGTGGGTGATCGATGGAGGGAGGGCGCAATTAAACATCGCTTTAGAAATTTTAAAAAGCAGCGGGAGT
TTTGTAGAAGTGATCGCTATTTCTAAAGAAAAAAGGGATTCTAAAGCTTATCGCTCTAAAGGGGGCGCTAAAGACATTAT
CCACACCGCTAACGATACTTTTAAATTGCTCCCTAGCGACAAGCGCTTGCAGTGGGTGCAAAAATTGCGCGATGAAAGCC
ACCGGTATGCGATAAACTTCCATAGATCCACTAAACTTAAAAACATGAAACAAATCGCTCTTTTAAAAGAAAAGGGTATA
GGAGAAGCCAGCGTGAAAAAATTATTGGATTATTTTGGGAGTTTTGAAGCGATAGAAAAAGCGAGCGAGCAGGAAAAAAA
CGCCGTTTTAAAAAAACGAATCTAA

Domains

Predicted by InterproScan.

GIY-YIG catalytic domain (GIY-YIG)

(15-98)

UvrB/uvrC motif (UVR)

(205-239)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(385-538)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

96.633

100

0.966