Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   MPG10_RS03215 Genome accession   NZ_CP094051
Coordinates   652446..654230 (-) Length   594 a.a.
NCBI ID   WP_245061715.1    Uniprot ID   -
Organism   Helicobacter pylori strain Hpfe127     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 647446..659230
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MPG10_RS03185 (MPG10_03185) - 648042..648290 (+) 249 WP_000790557.1 RNA-binding protein -
  MPG10_RS03190 (MPG10_03190) - 648487..649308 (-) 822 WP_245061710.1 glycosyltransferase family 25 protein -
  MPG10_RS03195 (MPG10_03195) trxB 649475..650410 (-) 936 WP_245061711.1 thioredoxin-disulfide reductase -
  MPG10_RS03200 (MPG10_03200) trxA 650416..650736 (-) 321 WP_000020200.1 thioredoxin -
  MPG10_RS03205 (MPG10_03205) - 650825..651169 (-) 345 WP_001211669.1 YraN family protein -
  MPG10_RS03210 (MPG10_03210) - 651170..652435 (-) 1266 WP_245061713.1 homoserine dehydrogenase -
  MPG10_RS03215 (MPG10_03215) uvrC 652446..654230 (-) 1785 WP_245061715.1 excinuclease ABC subunit UvrC Machinery gene
  MPG10_RS03220 (MPG10_03220) - 654231..654692 (-) 462 WP_220965258.1 hypothetical protein -
  MPG10_RS03225 (MPG10_03225) - 654684..654863 (+) 180 WP_000468796.1 hypothetical protein -
  MPG10_RS03230 (MPG10_03230) - 654875..655516 (-) 642 WP_245061717.1 ABC transporter ATP-binding protein -
  MPG10_RS03235 (MPG10_03235) - 655520..657181 (-) 1662 WP_245061719.1 ABC transporter permease/substrate-binding protein -
  MPG10_RS03240 (MPG10_03240) - 657362..657799 (-) 438 WP_180496053.1 hypothetical protein -
  MPG10_RS03245 (MPG10_03245) motB 657803..658570 (-) 768 WP_245061721.1 flagellar motor protein MotB -

Sequence

Protein


Download         Length: 594 a.a.        Molecular weight: 68568.71 Da        Isoelectric Point: 9.5791

>NTDB_id=666117 MPG10_RS03215 WP_245061715.1 652446..654230(-) (uvrC) [Helicobacter pylori strain Hpfe127]
MADLLSSLKNLSHSSGVYQYFDKNRQLLYIGKAKNLKKRIRSYFSVRNNEITPNCRASLRIQMMVKQIAFLETILVENEQ
DALILENSLIKQLKPKYNILLRDDKTYPYIYMDFSTDFPIPLITRKILKQPGVKYFGPFTSGAKDILDSLYELLPLVQKK
NCIKDKKACMFYQIERCKAPCENKITKEEYSKIAKECLEMIENKDKLIKELESKMEHLSNNLRFEEALIYKDRIAKIQKI
APFTCMDLAKLYDLDIFAFYSGSHKAVLVKMFMRGGKIISSAFEKIHSLNGFDTDEAMKQAIINHYQSHLPLMPEQILLN
ACSNETLKELQEFISHQYSKKIALSIPKKGDKLALIEIAMKNAQEIFSQEKTSSEDLILEEAQSLFKLECMPYRVEIFDA
SHHANSQCVGGMVVYENHEFQKNSYRRYHLKGSNEYTQMSELLTRRALDFAKDPPPNLWVIDGGRAQLNIALEILKSSGS
FVEVIAISKEKRDSKAYRSKGGAKDIIHTASDTFKLLPSDKRLQWVQKLRDESHRYAINFHRSTKLKNMKQIALLKEKGI
GEASVKKLLDYFGSFEAIEKASEQEKNAVLKKRI

Nucleotide


Download         Length: 1785 bp        

>NTDB_id=666117 MPG10_RS03215 WP_245061715.1 652446..654230(-) (uvrC) [Helicobacter pylori strain Hpfe127]
ATGGCTGATTTATTGTCCAGTTTGAAAAACCTTTCTCATAGCAGTGGCGTGTATCAATATTTTGATAAAAACCGCCAATT
ACTCTATATCGGTAAGGCGAAAAATTTAAAAAAGCGCATCAGAAGCTATTTTTCTGTCCGCAATAATGAAATCACACCCA
ATTGTCGCGCAAGCTTACGAATCCAAATGATGGTCAAACAGATCGCTTTTTTAGAAACCATTTTAGTGGAAAACGAACAA
GACGCTTTGATTTTAGAAAATTCTTTAATCAAGCAGCTCAAACCCAAATACAACATTCTTTTAAGAGACGATAAAACTTA
CCCTTATATTTATATGGATTTTTCCACTGATTTCCCTATCCCTTTAATCACACGAAAAATTTTAAAACAGCCTGGCGTTA
AATATTTTGGCCCTTTTACGAGCGGGGCTAAAGATATTTTAGACAGCTTGTATGAATTGCTCCCGTTAGTTCAAAAGAAA
AATTGCATCAAAGATAAAAAGGCATGCATGTTTTATCAAATAGAGCGTTGTAAAGCCCCATGCGAGAATAAAATCACCAA
AGAAGAGTATTCAAAAATCGCTAAAGAATGTTTAGAAATGATTGAAAATAAAGACAAACTCATCAAAGAGCTTGAATCAA
AAATGGAGCACCTTTCTAATAACTTGCGTTTTGAAGAAGCCCTCATTTATAAGGACAGGATTGCAAAAATCCAAAAAATC
GCCCCTTTCACTTGCATGGATTTAGCCAAACTCTACGATTTGGATATTTTTGCTTTTTATAGTGGGAGCCATAAGGCGGT
GTTAGTGAAAATGTTTATGCGTGGGGGTAAAATCATTTCTTCAGCGTTTGAAAAAATCCACTCTCTTAATGGGTTTGACA
CTGATGAAGCGATGAAACAAGCCATTATCAATCATTACCAATCGCATTTGCCTTTGATGCCTGAACAAATCTTATTGAAC
GCTTGCTCTAATGAAACGCTTAAAGAATTGCAAGAATTTATCTCTCACCAATACTCTAAAAAAATCGCTCTTAGTATTCC
TAAAAAAGGCGATAAGCTCGCTTTAATAGAAATCGCTATGAAAAACGCTCAAGAGATTTTTAGCCAAGAAAAAACCTCTA
GTGAAGATCTGATTTTAGAAGAAGCGCAATCGCTTTTTAAATTAGAGTGCATGCCTTATAGGGTGGAAATCTTTGATGCA
AGCCACCATGCCAACAGCCAATGCGTGGGGGGAATGGTCGTGTATGAAAATCATGAATTTCAAAAAAACTCCTATCGGCG
CTACCATTTAAAAGGCTCTAATGAATACACTCAAATGAGCGAATTGCTCACCAGAAGGGCTTTAGATTTTGCCAAAGATC
CACCGCCTAATTTGTGGGTGATCGATGGAGGGAGGGCGCAATTAAACATCGCTTTAGAAATTTTAAAAAGCAGCGGGAGT
TTTGTAGAAGTGATCGCTATTTCTAAAGAAAAAAGGGATTCTAAAGCTTATCGCTCTAAAGGGGGCGCTAAAGACATTAT
CCATACCGCTAGCGATACTTTTAAATTGCTCCCTAGCGACAAGCGCTTGCAGTGGGTGCAAAAATTGCGCGATGAAAGCC
ACCGGTATGCGATAAACTTCCATAGATCCACTAAACTTAAAAACATGAAACAAATCGCTCTTTTAAAAGAAAAGGGTATA
GGAGAAGCCAGCGTGAAAAAATTATTGGATTATTTTGGGAGTTTTGAAGCGATAGAAAAAGCGAGCGAGCAGGAAAAAAA
CGCCGTTTTAAAAAAACGAATTTAA

Domains

Predicted by InterproScan.

UvrB/uvrC motif (UVR)

(205-239)

GIY-YIG catalytic domain (GIY-YIG)

(15-98)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(384-538)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

95.96

100

0.96