Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraS   Type   Regulator
Locus tag   MQP46_RS09945 Genome accession   NZ_CP093935
Coordinates   1999073..2000116 (-) Length   347 a.a.
NCBI ID   WP_001017131.1    Uniprot ID   A0A0D1IMN4
Organism   Staphylococcus aureus strain WA121-2021_16354     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1994073..2005116
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MQP46_RS09915 (MQP46_09915) - 1994494..1995750 (-) 1257 WP_078098242.1 aminopeptidase -
  MQP46_RS09920 (MQP46_09920) - 1995753..1995953 (-) 201 WP_000180460.1 DUF1128 family protein -
  MQP46_RS09925 (MQP46_09925) - 1996100..1996564 (+) 465 WP_000228666.1 low molecular weight protein-tyrosine-phosphatase -
  MQP46_RS09930 (MQP46_09930) - 1996571..1996846 (+) 276 WP_000428172.1 YtxH domain-containing protein -
  MQP46_RS09935 (MQP46_09935) - 1997124..1998341 (+) 1218 WP_000037075.1 YihY/virulence factor BrkB family protein -
  MQP46_RS09940 (MQP46_09940) vraR 1998454..1999083 (-) 630 WP_000153535.1 two-component system response regulator VraR Regulator
  MQP46_RS09945 (MQP46_09945) vraS 1999073..2000116 (-) 1044 WP_001017131.1 sensor histidine kinase Regulator
  MQP46_RS09950 (MQP46_09950) liaF 2000113..2000814 (-) 702 WP_000149064.1 cell wall-active antibiotics response protein LiaF -
  MQP46_RS09955 (MQP46_09955) - 2000829..2001215 (-) 387 WP_001110179.1 hypothetical protein -
  MQP46_RS09960 (MQP46_09960) map 2001432..2002190 (-) 759 WP_000636142.1 type I methionyl aminopeptidase -
  MQP46_RS09965 (MQP46_09965) - 2002662..2003648 (+) 987 WP_000999717.1 aromatic acid exporter family protein -
  MQP46_RS09970 (MQP46_09970) - 2004079..2004492 (-) 414 WP_001557448.1 hypothetical protein -
  MQP46_RS09975 (MQP46_09975) - 2004521..2004631 (-) 111 WP_001790257.1 hypothetical protein -

Sequence

Protein


Download         Length: 347 a.a.        Molecular weight: 40044.52 Da        Isoelectric Point: 6.0577

>NTDB_id=665736 MQP46_RS09945 WP_001017131.1 1999073..2000116(-) (vraS) [Staphylococcus aureus strain WA121-2021_16354]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide


Download         Length: 1044 bp        

>NTDB_id=665736 MQP46_RS09945 WP_001017131.1 1999073..2000116(-) (vraS) [Staphylococcus aureus strain WA121-2021_16354]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(249-340)

Histidine kinase (HisKA_3)

(147-210)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0D1IMN4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraS Staphylococcus aureus N315

100

100

1