Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpE   Type   Regulator
Locus tag   SCSC_RS06740 Genome accession   NZ_AP014647
Coordinates   1387108..1389387 (+) Length   759 a.a.
NCBI ID   WP_006269743.1    Uniprot ID   A0AAD2SW64
Organism   Streptococcus constellatus subsp. constellatus strain CCUG 24889     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1382108..1394387
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SCSC_RS06710 (SCSC_1377) - 1382646..1382795 (-) 150 WP_006269755.1 hypothetical protein -
  SCSC_RS06715 (SCSC_1378) - 1383034..1383576 (-) 543 WP_006269752.1 ClbS/DfsB family four-helix bundle protein -
  SCSC_RS06720 (SCSC_1379) - 1383708..1383845 (-) 138 WP_003071957.1 FeoB-associated Cys-rich membrane protein -
  SCSC_RS06725 (SCSC_1380) feoB 1383854..1385998 (-) 2145 WP_006269754.1 ferrous iron transport protein B -
  SCSC_RS06730 (SCSC_1381) - 1385995..1386471 (-) 477 WP_006269767.1 FeoA family protein -
  SCSC_RS06735 (SCSC_1382) - 1386639..1386869 (-) 231 WP_006267994.1 DUF1797 family protein -
  SCSC_RS06740 (SCSC_1383) clpE 1387108..1389387 (+) 2280 WP_006269743.1 ATP-dependent Clp protease ATP-binding subunit Regulator
  SCSC_RS06745 (SCSC_1384) - 1389434..1390039 (-) 606 WP_006269751.1 GyrI-like domain-containing protein -
  SCSC_RS06750 (SCSC_1385) - 1390099..1390821 (-) 723 WP_003068187.1 WYL domain-containing protein -
  SCSC_RS06755 (SCSC_1386) - 1390787..1390990 (-) 204 WP_003068185.1 HTH domain-containing protein -
  SCSC_RS06760 (SCSC_1387) - 1391147..1391596 (+) 450 WP_003068183.1 NUDIX hydrolase -
  SCSC_RS06765 (SCSC_1388) - 1391661..1391960 (+) 300 WP_003068181.1 DUF1827 family protein -
  SCSC_RS06770 - 1392194..1392997 (-) 804 Protein_1324 IS982 family transposase -
  SCSC_RS06775 (SCSC_1390) - 1393187..1393732 (-) 546 WP_006269458.1 class I SAM-dependent methyltransferase -

Sequence

Protein


Download         Length: 759 a.a.        Molecular weight: 84755.98 Da        Isoelectric Point: 5.0266

>NTDB_id=66572 SCSC_RS06740 WP_006269743.1 1387108..1389387(+) (clpE) [Streptococcus constellatus subsp. constellatus strain CCUG 24889]
MLCQNCKINESTIHLYTNVNGKQHQVDLCQNCYQIMKTDPNNALFRGMTNMNNQNNLDPFDDFFSNLGNFQNHQEPQTPP
TQSGGGYGNGGYGSNQGGSTRQQVPQQPKGLLEEFGINVTEFARRGEIDPVIGRDEEIVRVIEILNRRTKNNPVLIGEPG
VGKTAVVEGLAQKIVDGDVPHKLQGKEVIRLDVVSLVQGTGIRGQFEERMQKLMNEIRSRQDVILFIDEIHEIVGAGSAG
DGNMDAGNILKPALARGELQLVGATTLNEYRIIEKDAALERRMQPVKVDEPTVEETITILKGIQKKYEDYHHVKYTDDAI
EAAAVLSNRYIQDRFLPDKAIDLLDEAGSKMNLTLNFVDPKIIDQRLVEAENLKAQATRDEDFEKAAYFRDQIAKYKEMQ
QNKMADQDTPLISEKTIEHIIEQKTNIPVGDLKEKEQSQLISLADDLKAHVIGQDDAVDKIAKAIRRNRVGLGTPDRPIG
SFLFVGPTGVGKTELSKQLAIELFGSADSMIRFDMSEYMEKHSVAKLVGAPPGYIGYEEAGQLTERVRRNPYSLILLDEI
EKAHPDVMHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGTGKVEANVGFGAAREGRTNSVIGELGNFFSPEFMNRFD
GIIEFKSLSKENLLQIVDLMLEDVNKRLAVNGIHLDVTDKVKEKLVNLGYDPKMGARPLRRTIQDHIEDAITDYYLEHPS
EKELKAVMTSNSKIVIKSSKKSENETEKEIKTTADDTAN

Nucleotide


Download         Length: 2280 bp        

>NTDB_id=66572 SCSC_RS06740 WP_006269743.1 1387108..1389387(+) (clpE) [Streptococcus constellatus subsp. constellatus strain CCUG 24889]
ATGCTTTGTCAAAATTGTAAAATAAACGAATCAACTATTCACCTTTACACAAATGTGAATGGAAAACAACACCAAGTTGA
CCTCTGTCAAAATTGTTATCAAATCATGAAAACAGACCCAAATAATGCCTTATTTCGTGGCATGACCAATATGAACAATC
AAAATAATTTAGACCCTTTTGATGATTTCTTTAGCAATCTAGGGAATTTTCAAAATCATCAAGAACCGCAGACCCCTCCT
ACTCAATCAGGTGGCGGATACGGCAACGGAGGCTATGGTTCCAATCAAGGTGGCAGCACGCGCCAACAAGTACCACAACA
ACCCAAAGGCCTCCTAGAAGAATTTGGTATCAATGTAACTGAATTTGCTCGGCGGGGCGAGATTGACCCTGTAATTGGTC
GTGACGAAGAAATTGTGCGCGTCATTGAAATCCTCAATCGTAGAACGAAGAACAATCCTGTCCTCATCGGAGAGCCCGGT
GTCGGTAAAACAGCAGTTGTCGAAGGCTTGGCTCAGAAAATTGTAGACGGTGATGTGCCACATAAACTCCAAGGCAAAGA
AGTCATTCGTTTAGATGTCGTTAGTTTGGTTCAAGGGACTGGGATCCGTGGTCAATTTGAAGAACGAATGCAAAAACTCA
TGAACGAAATTCGCTCTCGTCAGGATGTTATATTATTCATTGATGAAATTCACGAAATTGTTGGAGCTGGTTCTGCTGGC
GATGGAAATATGGATGCTGGAAACATCCTAAAACCAGCACTTGCTCGCGGTGAACTCCAATTAGTCGGTGCCACAACTCT
CAATGAATACCGGATTATCGAAAAAGATGCTGCACTGGAACGCCGTATGCAGCCTGTAAAAGTTGATGAACCAACAGTTG
AAGAAACGATCACTATCCTCAAAGGTATTCAAAAGAAATACGAAGACTATCACCACGTCAAATACACAGACGATGCCATT
GAAGCAGCAGCTGTCTTGTCCAATCGTTATATCCAAGATCGCTTCTTGCCTGATAAGGCCATTGACTTGCTAGACGAAGC
AGGCTCTAAGATGAATCTGACACTTAACTTTGTCGATCCAAAAATCATTGATCAACGATTGGTAGAAGCTGAAAACCTCA
AGGCACAAGCTACTCGTGATGAAGATTTTGAAAAAGCTGCTTATTTCCGTGACCAAATTGCCAAATACAAAGAAATGCAG
CAAAATAAAATGGCTGATCAAGATACGCCTCTTATCAGTGAAAAAACCATTGAACATATCATTGAGCAAAAGACAAATAT
TCCAGTTGGCGACTTGAAAGAAAAGGAACAATCACAATTGATTAGTCTGGCTGATGATTTGAAAGCTCATGTCATTGGTC
AAGATGATGCTGTTGATAAAATTGCGAAGGCCATTCGCCGTAATCGAGTTGGACTAGGTACACCAGACCGACCAATTGGT
TCTTTCCTTTTTGTTGGGCCAACCGGTGTCGGCAAAACAGAACTTTCTAAACAACTAGCGATTGAGCTCTTTGGTTCAGC
TGACAGCATGATTCGTTTTGATATGAGTGAGTATATGGAAAAACATAGCGTAGCAAAACTCGTCGGAGCGCCTCCAGGTT
ACATTGGCTACGAAGAAGCTGGACAATTAACAGAACGTGTACGTCGTAATCCTTATTCTCTCATTTTACTTGATGAAATA
GAAAAAGCTCACCCAGATGTCATGCATATGTTCTTACAAGTACTGGATGACGGACGTCTGACAGATGGACAAGGTCGGAC
AGTCAGTTTCAAAGATACGATTATCATTATGACTTCCAACGCCGGTACTGGAAAAGTCGAAGCAAACGTTGGATTTGGTG
CAGCGCGTGAAGGACGAACTAATTCTGTTATCGGTGAATTAGGAAACTTCTTCAGTCCAGAATTTATGAACCGTTTCGAT
GGTATTATTGAGTTCAAATCTCTTAGCAAGGAAAATCTCCTACAAATCGTAGATTTGATGCTTGAAGATGTGAATAAACG
CTTAGCTGTAAATGGTATTCACCTAGACGTAACAGACAAAGTCAAGGAAAAATTAGTTAATCTTGGTTACGATCCAAAAA
TGGGAGCTCGTCCACTTCGTCGGACAATCCAAGATCACATCGAGGATGCTATCACCGACTACTATCTTGAACATCCAAGC
GAAAAAGAGCTCAAAGCTGTCATGACGAGCAATAGCAAGATTGTTATCAAGTCGTCCAAAAAGTCTGAAAACGAGACCGA
AAAAGAAATTAAAACAACAGCAGACGACACTGCTAACTGA

Domains

Predicted by InterproScan.

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(648-722)

ATPase family associated with various cellular activities (AAA) (AAA)

(154-273)

AAA lid domain (AAA_lid_9)

(292-389)

AAA domain (Cdc48 subfamily) (AAA_2)

(477-640)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpE Streptococcus pneumoniae Rx1

86.702

99.078

0.859
  clpE Streptococcus pneumoniae D39

86.702

99.078

0.859
  clpE Streptococcus pneumoniae R6

86.702

99.078

0.859
  clpE Streptococcus pneumoniae TIGR4

86.702

99.078

0.859
  clpE Streptococcus mutans UA159

84.321

100

0.843
  clpC Lactococcus lactis subsp. cremoris KW2

76.09

99.736

0.759
  clpC Bacillus subtilis subsp. subtilis str. 168

49.857

91.963

0.459
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

47.239

85.903

0.406
  clpC Streptococcus pneumoniae Rx1

48.232

81.95

0.395
  clpC Streptococcus pneumoniae D39

48.232

81.95

0.395
  clpC Streptococcus pneumoniae TIGR4

48.071

81.95

0.394
  clpC Streptococcus thermophilus LMG 18311

46.955

82.213

0.386
  clpC Streptococcus mutans UA159

46.955

82.213

0.386
  clpC Streptococcus thermophilus LMD-9

47.03

82.082

0.386

Multiple sequence alignment