Detailed information NTG0665690

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: MQP45_RS09935
• Genome accession: NZ_CP093933
• Coordinates: 1995302..1996345 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain WA121-2021_15363
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1990302..2001345

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MQP45_RS09905 (MQP45_09905)	-	1990723..1991979 (-)	1257	WP_078098242.1	aminopeptidase	-
MQP45_RS09910 (MQP45_09910)	-	1991982..1992182 (-)	201	WP_000180460.1	DUF1128 family protein	-
MQP45_RS09915 (MQP45_09915)	-	1992329..1992793 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
MQP45_RS09920 (MQP45_09920)	-	1992800..1993075 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
MQP45_RS09925 (MQP45_09925)	-	1993353..1994570 (+)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
MQP45_RS09930 (MQP45_09930)	vraR	1994683..1995312 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
MQP45_RS09935 (MQP45_09935)	vraS	1995302..1996345 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
MQP45_RS09940 (MQP45_09940)	liaF	1996342..1997043 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
MQP45_RS09945 (MQP45_09945)	-	1997058..1997444 (-)	387	WP_001110179.1	hypothetical protein	-
MQP45_RS09950 (MQP45_09950)	map	1997661..1998419 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
MQP45_RS09955 (MQP45_09955)	-	1998891..1999877 (+)	987	WP_000999717.1	aromatic acid exporter family protein	-
MQP45_RS09960 (MQP45_09960)	-	2000308..2000721 (-)	414	WP_001557448.1	hypothetical protein	-
MQP45_RS09965 (MQP45_09965)	-	2000750..2000860 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=665690 MQP45_RS09935 WP_001017131.1 1995302..1996345(-) (vraS) [Staphylococcus aureus strain WA121-2021_15363]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=665690 MQP45_RS09935 WP_001017131.1 1995302..1996345(-) (vraS) [Staphylococcus aureus strain WA121-2021_15363]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1