Detailed information NTG0066540

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: SCSC_RS00690
• Genome accession: NZ_AP014647
• Coordinates: 130805..133234 (+)
• Length: 809 a.a.
• NCBI ID: WP_006269705.1
• Uniprot ID: A0AAD2SXF3
• Organism: Streptococcus constellatus subsp. constellatus strain CCUG 24889
• Function: degradation of ComW (predicted from homology) Competence regulation

Genomic Context

Location: 125805..138234

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SCSC_RS00660 (SCSC_0132)	-	126303..127088 (+)	786	WP_003071095.1	hypothetical protein	-
SCSC_RS00670 (SCSC_0134)	rpsB	127731..128513 (+)	783	WP_006269699.1	30S ribosomal protein S2	-
SCSC_RS00675 (SCSC_0135)	tsf	128596..129639 (+)	1044	WP_006269703.1	translation elongation factor Ts	-
SCSC_RS00680 (SCSC_0136)	-	129729..130079 (-)	351	WP_003071086.1	hypothetical protein	-
SCSC_RS00685 (SCSC_0137)	-	130340..130801 (+)	462	WP_006269722.1	CtsR family transcriptional regulator	-
SCSC_RS00690 (SCSC_0138)	clpC	130805..133234 (+)	2430	WP_006269705.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
SCSC_RS00695 (SCSC_0139)	-	133281..133721 (+)	441	WP_006269712.1	GNAT family N-acetyltransferase	-
SCSC_RS00700 (SCSC_0140)	dusB	133792..134763 (-)	972	WP_006269716.1	tRNA dihydrouridine synthase DusB	-
SCSC_RS00705 (SCSC_0141)	hslO	134750..135622 (-)	873	WP_006269717.1	Hsp33 family molecular chaperone HslO	-
SCSC_RS00710 (SCSC_0142)	-	135831..137102 (-)	1272	WP_006269710.1	toxic anion resistance protein	-
SCSC_RS00715 (SCSC_0143)	-	137121..137939 (-)	819	WP_006269727.1	hypothetical protein	-

Sequence

Protein

• Length: 809 a.a.
• Molecular weight: 89913.25 Da
• Isoelectric Point: 6.3637

>NTDB_id=66540 SCSC_RS00690 WP_006269705.1 130805..133234(+) (clpC) [Streptococcus constellatus subsp. constellatus strain CCUG 24889]
MKHSKALTESIESAQLLASHFETDYLESWQLLIAMANNPYSVAGSVLNDYPLEIDDFEKAAFHITGKVYQQEGAFTIWPF
SYRMKVLFLTAEQIAEAVHAKNLGTEHVLLAMLFDRGSLAARILEFIGFSYEDKEGALRMTDLRKNLEHKASWNKEDLKA
IRHLNKNAAATRQTMANMMGMPPATSGGLEDYTRDLTEMAHMGLLEPVIGRDKEISRMLQILSCKTKNNPVLVGDAGVGK
TALALGLAQRVAAGQVPNELAKMRVLELDLMNVVAGTRFRGDFEERMKNIINDIEADGHVILFIDELHTIMGSGSGIDST
LDAANILKPALARGTLRTVGATTQEEYQKYIEKDAALSRRFAKVAIEEPTVADSIAILQGLKKTYEDHHKVVITDSAIET
AVKYAYRYLTSKHLPDSAIDLLDEAAATVQNKGPQNHVKAELSAADEALMAGNWNKVSTLLEKESQPIVYKLRVKDEDVL
ATLSSLSGIPVQKLTQTDAKKYLNLEKELHKRVIGQNEAISAISRAIRRNQSGIRTSKRPIGSFMFLGPTGVGKTELAKA
LAEVLFDDETALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNRPYSVLLFDEVEKAHPDIFNVLLQVLDDG
VLTDSKGRKVDFSNTIIIMTSNLGATSLRDDKTVGFGARDVHFDHESMEKRMMEELKKSYRPEFINRIDEKVVFHSLTSE
DMQEVVKIMVQPLISSLAEKGIKLKFQPSALKLLAQEGYDPEMGARPLRRILQTRVEDHLSELLLAGELKTGQSLKVGVK
AGKLKFEVL

Nucleotide

• Length: 2430 bp

>NTDB_id=66540 SCSC_RS00690 WP_006269705.1 130805..133234(+) (clpC) [Streptococcus constellatus subsp. constellatus strain CCUG 24889]
ATGAAACATTCAAAAGCTTTGACAGAAAGTATTGAATCAGCACAGCTATTAGCAAGTCATTTTGAAACGGATTATTTAGA
GTCTTGGCAGCTGTTGATTGCTATGGCAAATAATCCTTATAGTGTTGCTGGTTCAGTTTTAAATGATTATCCACTTGAAA
TTGATGATTTTGAAAAGGCGGCTTTTCATATCACGGGGAAAGTCTATCAACAAGAGGGAGCTTTTACTATTTGGCCGTTT
TCTTATCGCATGAAAGTGTTATTTTTGACTGCTGAACAAATTGCAGAGGCGGTTCATGCCAAGAACCTTGGGACAGAGCA
TGTGTTGCTAGCTATGTTATTTGACCGAGGAAGTTTGGCAGCGCGTATTCTTGAATTTATTGGTTTTAGTTACGAAGATA
AAGAAGGTGCTCTACGCATGACAGATCTTCGGAAAAATTTAGAGCATAAGGCAAGCTGGAATAAAGAGGATTTAAAGGCG
ATTCGTCACCTAAATAAAAATGCTGCAGCAACAAGACAAACGATGGCTAATATGATGGGAATGCCTCCTGCAACCAGTGG
CGGACTAGAAGATTATACTCGTGATCTAACTGAAATGGCTCATATGGGCCTTTTAGAACCGGTCATTGGGCGGGATAAAG
AGATTTCTCGCATGCTTCAGATTTTAAGTTGCAAGACGAAAAATAATCCAGTTTTGGTAGGAGATGCAGGAGTTGGGAAG
ACAGCATTAGCCCTTGGTTTGGCGCAACGTGTGGCAGCTGGTCAAGTTCCAAATGAGCTTGCAAAGATGAGAGTTTTAGA
GCTAGATTTAATGAATGTGGTGGCTGGAACTCGTTTTCGTGGTGATTTTGAGGAACGGATGAAGAATATTATCAATGATA
TTGAAGCAGATGGACATGTCATTCTTTTCATTGATGAGCTTCATACTATTATGGGGTCGGGTAGCGGGATTGACTCGACA
TTAGATGCAGCGAACATTCTCAAGCCAGCTTTGGCCAGAGGGACACTCAGAACGGTCGGCGCAACGACACAAGAAGAGTA
CCAGAAATATATTGAAAAGGACGCAGCTCTTTCACGGCGCTTTGCTAAGGTTGCTATTGAAGAGCCAACAGTAGCTGATA
GTATTGCGATTTTACAAGGGCTAAAGAAAACTTATGAAGATCACCACAAGGTCGTGATTACGGATTCGGCCATTGAGACG
GCTGTTAAGTATGCTTATCGTTATCTAACAAGCAAACATCTACCGGATTCGGCCATTGATTTGCTAGATGAAGCCGCTGC
AACAGTACAAAATAAAGGTCCGCAAAATCACGTAAAAGCAGAATTAAGTGCAGCAGACGAGGCTTTAATGGCAGGCAATT
GGAACAAAGTTAGTACGTTGTTGGAGAAAGAGAGTCAGCCGATTGTCTATAAATTAAGGGTGAAAGACGAGGATGTTTTG
GCAACGCTCAGCAGTTTATCAGGTATTCCCGTGCAAAAGTTGACGCAAACAGATGCGAAGAAATACCTCAATTTAGAAAA
GGAACTGCACAAGCGGGTCATTGGGCAAAATGAAGCAATTTCTGCTATTAGTCGAGCGATTCGGCGCAATCAATCCGGTA
TCCGCACTAGCAAGCGTCCAATTGGCTCCTTTATGTTCTTAGGGCCAACCGGAGTCGGAAAAACTGAGCTAGCTAAGGCT
TTGGCAGAAGTTCTCTTTGATGACGAAACAGCACTGATTCGTTTTGATATGAGTGAATACATGGAAAAATTTGCTGCCAG
TCGCCTCAATGGAGCGCCTCCAGGTTATGTTGGTTATGAAGAAGGGGGCGAATTAACTGAAAAAGTTCGCAATCGTCCGT
ACTCTGTACTCCTCTTTGATGAGGTAGAAAAAGCACATCCTGATATTTTCAATGTGCTTCTCCAAGTCTTAGATGACGGG
GTGCTGACAGACAGCAAGGGGCGTAAGGTGGATTTTTCCAATACCATTATCATTATGACCAGCAATCTTGGTGCGACAAG
TTTGCGGGACGACAAGACGGTTGGTTTTGGAGCACGTGATGTTCACTTTGATCATGAAAGCATGGAAAAACGGATGATGG
AAGAGCTCAAGAAAAGTTATCGTCCAGAATTTATTAACCGAATTGATGAAAAGGTTGTTTTTCACAGTTTGACTAGCGAA
GACATGCAGGAAGTGGTGAAAATTATGGTGCAACCGCTCATTTCTAGTCTTGCAGAAAAAGGAATTAAACTCAAATTCCA
GCCGAGTGCTTTGAAGCTTCTAGCTCAAGAGGGCTATGATCCTGAAATGGGAGCTCGTCCATTGCGTCGAATTCTACAAA
CTCGGGTGGAAGACCATTTATCAGAATTACTTTTAGCAGGTGAGCTAAAAACGGGACAAAGCTTGAAAGTCGGTGTCAAG
GCTGGAAAATTGAAGTTTGAAGTGCTCTGA

Domains

Predicted by InterproScan.

• AAA domain (Cdc48 subfamily) (AAA_2) (539-710)

• AAA lid domain (AAA_lid_9) (371-449)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (14-60)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (91-134)

• ATPase family associated with various cellular activities (AAA) (AAA) (231-347)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (717-797)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Streptococcus pneumoniae TIGR4	76.942	100	0.771
clpC	Streptococcus pneumoniae Rx1	76.942	100	0.771
clpC	Streptococcus pneumoniae D39	76.942	100	0.771
clpC	Streptococcus mutans UA159	65.89	100	0.664
clpC	Streptococcus thermophilus LMG 18311	64.988	100	0.654
clpC	Streptococcus thermophilus LMD-9	64.865	100	0.653
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	49.639	100	0.509
clpC	Bacillus subtilis subsp. subtilis str. 168	45.262	99.135	0.449