Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OG254_RS38420 Genome accession   NZ_CP108659
Coordinates   8504364..8505044 (+) Length   226 a.a.
NCBI ID   WP_351199541.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_01092     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 8499364..8510044
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OG254_RS38395 (OG254_38300) - 8500495..8501253 (-) 759 WP_405591370.1 SDR family oxidoreductase -
  OG254_RS38400 (OG254_38305) - 8501387..8502013 (+) 627 WP_405591373.1 dihydrofolate reductase family protein -
  OG254_RS38405 (OG254_38310) - 8502167..8502553 (+) 387 WP_405591376.1 ribonuclease domain-containing protein -
  OG254_RS38410 (OG254_38315) - 8502614..8502814 (-) 201 WP_405591379.1 hypothetical protein -
  OG254_RS38415 (OG254_38320) - 8502993..8504237 (+) 1245 WP_405591382.1 sensor histidine kinase -
  OG254_RS38420 (OG254_38325) vraR 8504364..8505044 (+) 681 WP_351199541.1 response regulator transcription factor Regulator
  OG254_RS38425 (OG254_38330) - 8505089..8506267 (+) 1179 WP_405591385.1 cytochrome P450 -
  OG254_RS38430 (OG254_38335) - 8506302..8507324 (-) 1023 WP_405591388.1 Gfo/Idh/MocA family oxidoreductase -
  OG254_RS38435 (OG254_38340) - 8507454..8508191 (+) 738 WP_351199662.1 GntR family transcriptional regulator -
  OG254_RS38440 (OG254_38345) - 8508401..8509549 (+) 1149 WP_405591390.1 ROK family glucokinase -

Sequence

Protein


Download         Length: 226 a.a.        Molecular weight: 24086.57 Da        Isoelectric Point: 4.9810

>NTDB_id=664635 OG254_RS38420 WP_351199541.1 8504364..8505044(+) (vraR) [Streptomyces sp. NBC_01092]
MTAIRLLLVDDDPLVRAGLSFMLGGADDIEIVGEAADGAEVEALVDRTRPDVVLMDIRMPSVDGLTATERLRGRKDAPQV
VLLTTFHADDQVLRALRAGAAGFVLKDTPPAEIVAAVRRVAAGDPVLSPTVTRQLMDHAAGSAADTRRTRARARLTALND
REREVAVAVGRGLSNADIAAELFMSVATVKTHVSRVLAKLDLNNRVQIALLAYDAGLLEELEDGGH

Nucleotide


Download         Length: 681 bp        

>NTDB_id=664635 OG254_RS38420 WP_351199541.1 8504364..8505044(+) (vraR) [Streptomyces sp. NBC_01092]
ATGACTGCGATCAGACTCCTCCTCGTCGACGACGACCCGTTGGTCAGGGCCGGCCTGTCCTTCATGCTGGGCGGCGCCGA
CGACATCGAGATCGTCGGCGAGGCGGCGGACGGCGCGGAGGTCGAGGCGCTGGTCGACCGCACCCGGCCGGACGTGGTCC
TGATGGACATCCGGATGCCGTCGGTCGACGGCCTCACCGCCACGGAGCGGCTGCGCGGCAGGAAGGACGCCCCGCAGGTC
GTGCTGCTGACCACCTTCCACGCCGACGACCAGGTGCTGCGGGCCCTGCGCGCCGGCGCCGCCGGGTTCGTGCTCAAGGA
CACGCCGCCCGCCGAGATCGTCGCCGCGGTCCGCCGCGTCGCGGCCGGCGACCCGGTCCTGTCGCCCACCGTCACACGGC
AGTTGATGGACCACGCGGCCGGCTCCGCCGCCGACACCCGCCGCACGCGCGCACGCGCGCGGCTCACCGCCCTGAACGAC
CGCGAGCGCGAGGTCGCCGTCGCGGTGGGCCGTGGCCTGTCCAACGCCGACATCGCCGCCGAACTGTTCATGAGCGTCGC
CACCGTCAAGACCCATGTCTCCCGCGTCCTGGCCAAGCTCGACCTCAACAACCGGGTGCAGATTGCTCTGTTGGCGTACG
ACGCGGGACTCCTGGAGGAACTGGAGGACGGCGGGCACTAG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(158-212)

Response regulator receiver domain (Response_reg)

(7-118)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

37.9

96.903

0.367