Detailed information NTG0664546

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: MN088_RS11690
• Genome accession: NZ_CP093413
• Coordinates: 2292963..2293991 (-)
• Length: 342 a.a.
• NCBI ID: WP_010906347.1
• Uniprot ID: A0AAP4JQE3
• Organism: Lactococcus lactis strain AH1
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 2287963..2298991

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MN088_RS11665 (MN088_11665)	-	2288249..2288746 (-)	498	WP_021214977.1	nitroreductase family protein	-
MN088_RS11670 (MN088_11670)	-	2288733..2288942 (-)	210	WP_003132661.1	hypothetical protein	-
MN088_RS11675 (MN088_11675)	-	2288939..2289766 (-)	828	WP_010906344.1	radical SAM protein	-
MN088_RS11680 (MN088_11680)	-	2289759..2291882 (-)	2124	WP_010906345.1	radical SAM protein	-
MN088_RS11685 (MN088_11685)	-	2291985..2292842 (-)	858	WP_010906346.1	transcriptional regulator	-
MN088_RS11690 (MN088_11690)	sepM	2292963..2293991 (-)	1029	WP_010906347.1	SepM family pheromone-processing serine protease	Regulator
MN088_RS11695 (MN088_11695)	coaD	2293978..2294475 (-)	498	WP_010906348.1	pantetheine-phosphate adenylyltransferase	-
MN088_RS11700 (MN088_11700)	rsmD	2294523..2295062 (-)	540	WP_015427191.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
MN088_RS11705 (MN088_11705)	-	2295233..2296453 (-)	1221	WP_003132654.1	MFS transporter	-
MN088_RS11710 (MN088_11710)	lmrP	2296537..2297763 (-)	1227	WP_021214981.1	multidrug efflux MFS transporter LmrP	-
MN088_RS11715 (MN088_11715)	-	2297951..2298445 (+)	495	WP_010906351.1	RNA polymerase sigma factor	-

Sequence

Protein

• Length: 342 a.a.
• Molecular weight: 37379.98 Da
• Isoelectric Point: 9.9183

>NTDB_id=664546 MN088_RS11690 WP_010906347.1 2292963..2293991(-) (sepM) [Lactococcus lactis strain AH1]
MKKNKKINPKLKWGISIGLIVVALLALFYPTSYYVEMPGTTEPLGKMVKVEGKKDEHKGDFFLTTVQIARANLATMIYSH
FNSFTSIYSEQEMTGGLNDAQFNRVNQFYMETAQNTAIYQAFKLANKPYELKYEGVYVLDIAKNSTFKNKLELADTITAV
NGQQFTSSADMIAYVSKQKVGDSVTIEYTRIDGTKHKSTGKYIKIANGKTGIGISLVDHTEVVTTPKVTVNAGSIGGPSA
GMMFTLEIYSQLTGKDLRNGREIAGTGTIEHDGSIGQIGGVDKKVATASKEGAKVFLVPDSGTKKESSNNYLGAKTAAKK
LKTKMKIVPVKTIQDALDYLEK

Nucleotide

• Length: 1029 bp

>NTDB_id=664546 MN088_RS11690 WP_010906347.1 2292963..2293991(-) (sepM) [Lactococcus lactis strain AH1]
ATGAAAAAAAATAAAAAAATTAATCCCAAATTAAAATGGGGAATCTCGATTGGTCTAATTGTTGTTGCCCTTTTAGCTTT
ATTTTATCCAACGAGTTACTATGTGGAAATGCCCGGAACAACCGAGCCTTTAGGGAAAATGGTCAAAGTTGAAGGCAAAA
AAGATGAACATAAAGGTGATTTTTTCCTGACGACTGTCCAAATTGCACGAGCAAATCTTGCTACAATGATTTACAGCCAT
TTTAATAGTTTTACAAGCATTTACAGTGAGCAAGAAATGACTGGTGGACTTAACGACGCACAGTTCAACCGTGTCAACCA
GTTTTACATGGAAACGGCACAGAATACAGCGATTTATCAAGCTTTTAAATTAGCTAATAAACCTTATGAACTTAAATATG
AAGGCGTTTATGTCCTTGATATTGCCAAAAATTCGACCTTTAAAAATAAGCTAGAACTTGCAGATACGATTACAGCAGTC
AATGGTCAACAGTTTACATCAAGTGCCGACATGATTGCTTATGTTTCCAAACAAAAAGTCGGTGATTCAGTAACGATTGA
ATACACGAGAATTGACGGCACAAAGCACAAGTCAACTGGCAAATACATCAAAATTGCTAATGGAAAAACAGGAATTGGGA
TCAGCCTAGTTGACCATACTGAAGTCGTGACGACTCCAAAAGTTACTGTCAACGCGGGTTCAATCGGTGGTCCCTCTGCG
GGGATGATGTTTACACTAGAAATTTACAGTCAGTTGACAGGAAAAGATTTGCGAAACGGTCGCGAAATTGCTGGAACTGG
AACGATTGAACATGACGGAAGCATTGGCCAAATCGGCGGTGTTGATAAAAAAGTAGCCACAGCGAGCAAAGAAGGGGCAA
AGGTCTTCTTAGTGCCTGACTCAGGCACCAAAAAGGAAAGCAGCAACAATTACCTTGGAGCCAAAACCGCAGCTAAAAAA
CTAAAAACGAAGATGAAAATCGTTCCCGTCAAAACTATTCAGGACGCTTTAGATTATTTAGAAAAATAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (134-194)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (227-338)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	48.696	100	0.491