Detailed information NTG0663355

Bioinformatically predicted

Overview

• Name: disA
• Type: Machinery gene
• Locus tag: OG220_RS22330
• Genome accession: NZ_CP108582
• Coordinates: 5001121..5002242 (-)
• Length: 373 a.a.
• NCBI ID: WP_326688769.1
• Uniprot ID: -
• Organism: Streptomyces sp. NBC_01187
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 4996121..5007242

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
OG220_RS22310 (OG220_22300)	-	4996244..4996813 (-)	570	WP_326688773.1	TetR/AcrR family transcriptional regulator	-
OG220_RS22315 (OG220_22305)	-	4997195..4998820 (+)	1626	WP_405807458.1	MDR family MFS transporter	-
OG220_RS22320 (OG220_22310)	-	4998950..4999921 (-)	972	WP_326688771.1	A/G-specific adenine glycosylase	-
OG220_RS22325 (OG220_22315)	-	5000148..5001017 (+)	870	WP_405804943.1	hypothetical protein	-
OG220_RS22330 (OG220_22320)	disA	5001121..5002242 (-)	1122	WP_326688769.1	DNA integrity scanning diadenylate cyclase DisA	Machinery gene
OG220_RS22335 (OG220_22325)	radA/sms	5002568..5003956 (-)	1389	WP_326688768.1	DNA repair protein RadA	Machinery gene
OG220_RS22340 (OG220_22330)	-	5004166..5006052 (+)	1887	WP_405807460.1	hypothetical protein	-
OG220_RS22345 (OG220_22335)	-	5006093..5006908 (-)	816	WP_326688767.1	hypothetical protein	-

Sequence

Protein

• Length: 373 a.a.
• Molecular weight: 40065.84 Da
• Isoelectric Point: 4.9989

>NTDB_id=663355 OG220_RS22330 WP_326688769.1 5001121..5002242(-) (disA) [Streptomyces sp. NBC_01187]
MAANDRAAVPGRAEGASGLMRATLSAVAPGTALRDGLERVLRGNTGGLMVLGMDRTVEALCTGGFVLDVDFSATRLRELC
KLDGALILDGDISKIVRAGVQLVPDASIETEETGTRHRTAQRVSIQTGFPVVSVSQSMRLIALYVEGQRRVLEDSAAILS
RANQALATLERYKLRLDEVAGTLSALEIEDLVTVRDVTAVAQRLEMVRRIATEIAEYVVELGTDGRLLSLQLDELIAGVE
PERELVVRDYAPQAGGSGRRVRTVPEALSELDRLTHTELLELPTVARALGYSGAPETLDSAVSPRGFRLLAKVPRLPGTV
IDRLVDHFGGLQKLLAASVDDLQAVDGVGEARARSVREGLSRLAESSILERYV

Nucleotide

• Length: 1122 bp

>NTDB_id=663355 OG220_RS22330 WP_326688769.1 5001121..5002242(-) (disA) [Streptomyces sp. NBC_01187]
GTGGCAGCCAACGACCGGGCAGCGGTCCCCGGCAGGGCCGAGGGGGCGTCCGGCCTGATGCGCGCGACACTGAGCGCGGT
CGCACCGGGCACAGCCCTGCGCGACGGGCTGGAGCGCGTCCTGCGGGGGAACACCGGCGGCCTCATGGTCCTCGGCATGG
ACAGGACGGTCGAAGCGCTGTGCACCGGCGGCTTCGTCCTCGACGTGGACTTCAGCGCGACCCGGCTGCGCGAGCTGTGC
AAGCTGGACGGCGCGCTCATCCTCGACGGGGACATCTCCAAGATCGTCCGGGCCGGTGTGCAGCTCGTCCCCGACGCCTC
CATCGAGACCGAGGAGACGGGCACCCGGCACCGCACCGCCCAGCGCGTCTCGATCCAGACCGGCTTCCCGGTCGTCTCCG
TCAGCCAGTCCATGCGGCTGATCGCCCTCTACGTCGAGGGCCAGCGCCGCGTCCTGGAGGACTCGGCGGCGATCCTCTCC
CGTGCCAACCAGGCGCTGGCCACCCTGGAGCGCTACAAGCTGCGGCTCGACGAGGTCGCCGGCACGCTCTCCGCGCTGGA
GATCGAGGACCTGGTGACCGTCCGGGACGTCACGGCCGTCGCCCAGCGCCTGGAGATGGTGCGCAGGATCGCCACGGAGA
TCGCCGAGTACGTCGTGGAGCTGGGCACCGACGGACGGCTGCTCTCGCTCCAGCTCGACGAGCTGATCGCCGGGGTGGAG
CCCGAGCGCGAGCTGGTCGTGCGGGACTACGCGCCGCAGGCGGGCGGTTCGGGCCGCCGCGTGCGCACCGTGCCCGAGGC
GCTCAGCGAACTGGACCGGCTCACCCACACCGAGTTGCTCGAACTGCCCACGGTGGCACGGGCACTGGGCTACAGCGGGG
CCCCCGAGACGCTGGATTCCGCCGTCTCGCCGCGCGGCTTCCGGCTGCTGGCGAAGGTGCCGAGGCTGCCGGGGACCGTC
ATCGACCGGCTGGTGGACCACTTCGGCGGGCTTCAGAAGCTGCTCGCCGCGAGCGTGGACGACCTCCAGGCGGTGGACGG
CGTCGGCGAGGCCCGTGCCCGCTCGGTCCGCGAGGGCCTCTCGCGGCTGGCCGAGTCCTCGATCCTTGAGCGCTACGTCT
AG

Domains

Predicted by InterProScan.

• DisA bacterial checkpoint controller linker region (DisA-linker) (152-295)

• Helix-hairpin-helix motif (HHH_2) (323-358)

• DisA bacterial checkpoint controller nucleotide-binding (DAC) (35-148)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
disA	Bacillus subtilis subsp. subtilis str. 168	44.886	94.37	0.424