Detailed information NTG0662546

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: MNU50_RS07185
• Genome accession: NZ_CP093210
• Coordinates: 1538375..1539421 (-)
• Length: 348 a.a.
• NCBI ID: WP_001830374.1
• Uniprot ID: A0A0N1EGU4
• Organism: Staphylococcus epidermidis strain TSM-50
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1533375..1544421

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MNU50_RS07155 (MNU50_07140)	-	1533759..1535000 (-)	1242	WP_002457094.1	aminopeptidase	-
MNU50_RS07160 (MNU50_07145)	-	1535002..1535217 (-)	216	WP_001830421.1	DUF1128 domain-containing protein	-
MNU50_RS07165 (MNU50_07150)	-	1535358..1535822 (+)	465	WP_001830437.1	low molecular weight protein-tyrosine-phosphatase	-
MNU50_RS07170 (MNU50_07155)	-	1535830..1536114 (+)	285	WP_001830401.1	YtxH domain-containing protein	-
MNU50_RS07175 (MNU50_07160)	-	1536521..1537699 (+)	1179	WP_001830411.1	YihY/virulence factor BrkB family protein	-
MNU50_RS07180 (MNU50_07165)	vraR	1537756..1538385 (-)	630	WP_001830439.1	two-component system response regulator VraR	Regulator
MNU50_RS07185 (MNU50_07170)	vraS	1538375..1539421 (-)	1047	WP_001830374.1	sensor histidine kinase	Regulator
MNU50_RS07190 (MNU50_07175)	liaF	1539418..1540119 (-)	702	WP_002457093.1	cell wall-active antibiotics response protein LiaF	-
MNU50_RS07195 (MNU50_07180)	-	1540134..1540520 (-)	387	WP_001830382.1	hypothetical protein	-
MNU50_RS07200 (MNU50_07185)	map	1540678..1541433 (-)	756	WP_002457092.1	type I methionyl aminopeptidase	-
MNU50_RS07205 (MNU50_07190)	-	1541607..1542593 (+)	987	WP_002457091.1	aromatic acid exporter family protein	-
MNU50_RS07210 (MNU50_07195)	-	1542744..1543280 (-)	537	WP_001830372.1	hypothetical protein	-

Sequence

Protein

• Length: 348 a.a.
• Molecular weight: 40066.49 Da
• Isoelectric Point: 5.8512

>NTDB_id=662546 MNU50_RS07185 WP_001830374.1 1538375..1539421(-) (vraS) [Staphylococcus epidermidis strain TSM-50]
MNHYIRAIGSMLILVYSMLIAFLFIDKVFVNIIFFQGMFYTQIFGIPVFLFLNLLIVLLCIIVGSVLAYKINQQNDWIIS
QIERSIEGQTVGINDQNIELYTETIDIYHTLVPLNQELHRLRMKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKESKLEPPLNQQIPILEKMVQDSQLEMRALLLHLRPIGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFEVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNQEDYLLLRIQDNGKGFNVDEKFEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEENSSGD

Nucleotide

• Length: 1047 bp

>NTDB_id=662546 MNU50_RS07185 WP_001830374.1 1538375..1539421(-) (vraS) [Staphylococcus epidermidis strain TSM-50]
ATGAATCACTACATAAGAGCTATAGGCTCAATGCTTATATTAGTATATAGTATGCTTATTGCTTTTTTATTTATTGATAA
AGTGTTTGTAAATATTATCTTTTTTCAGGGGATGTTTTATACACAAATATTTGGAATACCTGTTTTTCTATTTTTAAATT
TATTAATTGTTCTTTTATGTATTATAGTTGGATCTGTTTTAGCTTATAAAATTAATCAACAAAATGATTGGATTATTTCA
CAAATAGAAAGATCAATAGAAGGACAAACAGTAGGTATCAATGATCAAAATATCGAATTATATACAGAAACGATAGATAT
TTATCATACACTAGTTCCATTAAATCAAGAATTACATCGACTTAGAATGAAGACTCAAAATTTAACTAATGAAAACTACA
ATATTAATGATGTAAAAGTCAAAAAGATTATCGAAGATGAGCGACAACGACTTGCCAGGGAATTACATGATTCTGTTAGT
CAACAATTATTTGCTGCGAGCATGATGCTATCGGCGATAAAAGAGTCGAAATTAGAACCACCTTTAAATCAACAGATACC
AATTCTTGAAAAAATGGTTCAAGACTCACAACTTGAAATGAGAGCTTTGTTATTACATTTAAGACCGATAGGTTTAAAAG
ATAAGTCTTTAGGTGAAGGAATTAAAGATTTAGTCATCGATTTACAAAAGAAAGTACCAATGAAAGTTGTGCATGAAATT
CAAGATTTTGAAGTGCCAAAAGGCATTGAAGATCACTTGTTCAGAATTACACAAGAAGCTATTTCAAATACATTGAGACA
TTCAAATGGTACAAAAGTAACTGTGGAATTATTTAATCAAGAGGATTATCTTTTACTAAGAATTCAAGATAATGGAAAAG
GATTTAATGTAGATGAAAAATTTGAACAAAGTTATGGTTTGAAAAATATGCGAGAACGAGCGTTAGAAATTGGTGCGACG
TTTCATATTGTATCTTTACCTGATTCAGGTACACGAATTGAAGTTAAGGCACCATTGAATAAGGAGGAGAATTCAAGTGG
CGATTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0N1EGU4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	93.023	98.851	0.92