Detailed information NTG0066243

Bioinformatically predicted

Overview

• Name: cytR
• Type: Regulator
• Locus tag: H7R04_RS21525
• Genome accession: NZ_AP022120
• Coordinates: 4540622..4541647 (+)
• Length: 341 a.a.
• NCBI ID: WP_000644904.1
• Uniprot ID: P0ACN8
• Organism: Escherichia coli strain WP5-W18-ESBL-11
• Function: promote competence gene expression (predicted from homology) Competence regulation

Genomic Context

Location: 4535622..4546647

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H7R04_RS21515 (WP5W18E11_41850)	rpmE	4537853..4538065 (-)	213	WP_000710769.1	50S ribosomal protein L31	-
H7R04_RS21520 (WP5W18E11_41860)	priA	4538268..4540466 (+)	2199	WP_001315935.1	primosomal protein N'	Machinery gene
H7R04_RS21525 (WP5W18E11_41870)	cytR	4540622..4541647 (+)	1026	WP_000644904.1	DNA-binding transcriptional regulator CytR	Regulator
H7R04_RS21530 (WP5W18E11_41880)	ftsN	4541739..4542698 (+)	960	WP_000068834.1	cell division protein FtsN	-
H7R04_RS21535 (WP5W18E11_41890)	hslV	4542791..4543321 (+)	531	WP_000208242.1	ATP-dependent protease subunit HslV	-
H7R04_RS21540 (WP5W18E11_41900)	hslU	4543331..4544662 (+)	1332	WP_001293343.1	HslU--HslV peptidase ATPase subunit	-
H7R04_RS21545 (WP5W18E11_41910)	menA	4544729..4545655 (+)	927	WP_001307494.1	1,4-dihydroxy-2-naphthoate polyprenyltransferase	-
H7R04_RS21550 (WP5W18E11_41920)	rraA	4545748..4546233 (+)	486	WP_000872908.1	ribonuclease E activity regulator RraA	-
H7R04_RS21555 (WP5W18E11_41930)	zapB	4546318..4546563 (-)	246	WP_001296623.1	septal ring assembly protein ZapB	-

Sequence

Protein

• Length: 341 a.a.
• Molecular weight: 37819.78 Da
• Isoelectric Point: 6.3842

>NTDB_id=66243 H7R04_RS21525 WP_000644904.1 4540622..4541647(+) (cytR) [Escherichia coli strain WP5-W18-ESBL-11]
MKAKKQETAATMKDVALKAKVSTATVSRALMNPDKVSQATRNRVEKAAREVGYLPQPMGRNVKRNESRTILVIVPDICDP
FFSEIIRGIEVTAANHGYLVLIGDCAHQNQQEKTFIDLIITKQIDGMLLLGSRLPFDASIEEQRNLPPMVMANEFAPELE
LPTVHIDNLTAAFDAVNYLYEQGHKRIGCIAGPEEMPLCHYRLQGYVQALRRCGIMVDPQYIARGDFTFEAGSKAMQQLL
DLPQPPTAVFCHSDVMALGALSQAKRQGLKVPEDLSIIGFDNIDLTQFCDPPLTTIAQPRYEIGREAMLLLLDQMQGQHV
GSGSRLMDCELIIRGSTRALP

Nucleotide

• Length: 1026 bp

>NTDB_id=66243 H7R04_RS21525 WP_000644904.1 4540622..4541647(+) (cytR) [Escherichia coli strain WP5-W18-ESBL-11]
GTGAAAGCGAAGAAGCAGGAAACTGCCGCGACCATGAAAGACGTTGCCCTCAAGGCAAAAGTCTCTACAGCGACTGTCTC
CCGAGCATTAATGAATCCCGATAAAGTCTCCCAGGCCACCCGTAATCGGGTTGAAAAAGCGGCCCGGGAAGTGGGTTATT
TACCGCAACCTATGGGGCGCAACGTCAAGCGTAATGAATCCCGCACCATTCTGGTGATTGTCCCGGATATCTGCGATCCC
TTCTTTAGCGAAATTATTCGCGGTATCGAAGTTACGGCGGCAAATCACGGATATCTGGTGCTGATTGGCGACTGTGCGCA
TCAAAATCAGCAGGAAAAAACCTTTATCGATTTGATCATCACCAAGCAAATTGATGGCATGTTGCTGCTGGGCTCAAGGC
TGCCGTTTGATGCCAGCATTGAGGAACAGCGTAATCTGCCGCCGATGGTGATGGCGAACGAATTTGCACCGGAACTGGAG
CTGCCTACCGTTCATATCGACAATCTGACCGCCGCATTTGATGCAGTAAATTATTTATATGAGCAAGGGCATAAACGGAT
TGGCTGTATAGCCGGTCCCGAAGAGATGCCACTGTGTCACTATCGCCTGCAAGGCTATGTTCAGGCGCTGCGTCGCTGCG
GCATTATGGTTGATCCGCAATACATCGCCCGTGGCGACTTCACCTTCGAAGCCGGAAGCAAAGCGATGCAGCAGCTGCTT
GATCTTCCACAACCGCCTACTGCTGTCTTCTGCCATAGCGATGTGATGGCGCTCGGCGCACTTTCTCAGGCAAAACGCCA
GGGGCTGAAAGTCCCGGAAGACCTTTCCATAATCGGTTTTGATAACATCGACCTGACGCAATTTTGTGATCCGCCGCTGA
CAACCATCGCGCAGCCGCGTTACGAAATCGGTCGGGAAGCTATGCTGTTATTGCTTGATCAAATGCAGGGGCAACACGTT
GGCAGTGGCTCTCGTTTAATGGACTGCGAACTTATCATCCGGGGATCAACACGCGCGTTACCTTAA

Domains

Predicted by InterProScan.

• Bacterial regulatory proteins, lacI family (LacI) (11-56)

• Periplasmic binding protein-like domain (Peripla_BP_3) (176-337)

3D structure

• AlphaFold DB: P0ACN8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
cytR	Vibrio parahaemolyticus RIMD 2210633	64.179	98.24	0.63
cytR	Vibrio cholerae C6706	65.443	95.894	0.628