Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrA   Type   Machinery gene
Locus tag   OG345_RS31060 Genome accession   NZ_CP108531
Coordinates   6998690..7001737 (+) Length   1015 a.a.
NCBI ID   WP_371604028.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_01220     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 6993690..7006737
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OG345_RS31040 (OG345_30995) - 6993864..6995828 (+) 1965 WP_371604026.1 TerD family protein -
  OG345_RS31045 (OG345_31000) - 6996090..6997103 (+) 1014 WP_306069725.1 TerC family protein -
  OG345_RS31050 (OG345_31005) - 6997158..6997814 (-) 657 WP_219572433.1 MBL fold metallo-hydrolase -
  OG345_RS31055 (OG345_31010) - 6997825..6998514 (-) 690 WP_371604027.1 maleylpyruvate isomerase family mycothiol-dependent enzyme -
  OG345_RS31060 (OG345_31015) uvrA 6998690..7001737 (+) 3048 WP_371604028.1 excinuclease ABC subunit UvrA Machinery gene
  OG345_RS31065 (OG345_31020) - 7002031..7002459 (+) 429 WP_219572436.1 Rieske (2Fe-2S) protein -
  OG345_RS31070 (OG345_31025) - 7002568..7003494 (-) 927 WP_328948130.1 hypothetical protein -
  OG345_RS31075 (OG345_31030) - 7003722..7004381 (+) 660 WP_371604029.1 papain-like cysteine protease family protein -
  OG345_RS31080 (OG345_31035) - 7004386..7005255 (+) 870 WP_371604030.1 hypothetical protein -

Sequence

Protein


Download         Length: 1015 a.a.        Molecular weight: 111289.90 Da        Isoelectric Point: 8.3351

>NTDB_id=662422 OG345_RS31060 WP_371604028.1 6998690..7001737(+) (uvrA) [Streptomyces sp. NBC_01220]
MADRLIVRGAREHNLKNVSLDLPRDSLIVFTGLSGSGKSSLAFDTIFAEGQRRYVESLSSYARQFLGQMDKPDVDFIEGL
SPAVSIDQKSTSRNPRSTVGTITEVYDYLRLLFARIGKPHCPECGRPISRQSPQAIVDKVLGLPEGSRFQVLSPLVRERK
GEFVDLFADLQTKGYSRARVDGATIQLSEPPTLKKQEKHTIEVVIDRLTVKDSAKRRLTDSVETALGLSGGMVVLDFVDL
PEDDPERERMYSEHLYCPYDDLSFEELEPRSFSFNSPFGACPDCTGIGTRMEVDPELIVPDEEKSLDEGAIHPWSHGHTK
EYFGRQINALAEALGFRTDIPWAGLPQRAKKALLFGHKIQTEVRYRNRYGRERAYTTPSFEGAVQFVKRRHSEAESDSSR
ERFEGYMREVPCPTCEGTRLKPIVLAVTVMEKSIAQVAAMSISECAEFLGRMKLNARDKKIAERVLKEVNERLKFLVDVG
LDYLSLNRAAGTLSGGEAQRIRLATQIGSGLVGVLYVLDEPSIGLHQRDNHRLIETLVRLRDMGNTLIVVEHDEDTIKVA
DWVVDIGPGAGEHGGKVVHSGSLKELLANDKSITGQYLTGKRSIAMPEIRRPVDPSRLLTVHGARENNLQDIDVAFPLGV
LTAVTGVSGSGKSTLVNDILYTHLARELNGAKSVPGRHTRVDGDDLVDKVVHVDQSPIGRTPRSNPATYTGVFDHVRRLF
AETMEAKVRGYLPGRFSFNVKGGRCENCSGDGTIKIEMNFLPDVYVPCEVCHGARYNRETLEVHYKGKSIAEVLDMPIEE
GLEFFEAVPTIARHLRTLNEVGLGYVRLGQSAPTLSGGEAQRVKLASELQKRSTGRTVYVLDEPTTGLHFEDISKLIKVL
SGLVDKGNSVIVIEHNLDVIKTADWVIDMGPEGGNGGGLVIAEGTPEFVAGVPASHTGKFLQGILDADRVSEAAVPAARK
PVRKTAAKKAVAAKSAPARKTATAKTPAKKATAKSTGTAAAKKPAAKKAPRARKA

Nucleotide


Download         Length: 3048 bp        

>NTDB_id=662422 OG345_RS31060 WP_371604028.1 6998690..7001737(+) (uvrA) [Streptomyces sp. NBC_01220]
GTGGCCGACCGTCTCATCGTCCGTGGCGCTCGCGAGCACAACCTCAAGAACGTCTCGCTCGACCTCCCCCGCGACTCCCT
CATCGTCTTCACCGGGCTCTCCGGGTCGGGCAAGTCGTCGCTCGCGTTCGACACGATCTTCGCCGAGGGCCAGCGGCGCT
ACGTGGAGTCCCTCTCCTCGTACGCCCGGCAGTTCCTCGGCCAGATGGACAAGCCGGACGTCGACTTCATCGAGGGCCTG
TCGCCCGCCGTCTCCATCGACCAGAAGTCGACCTCGCGCAACCCGCGCTCGACGGTCGGCACGATCACCGAGGTCTACGA
CTACCTCCGGCTGCTCTTCGCCAGGATCGGCAAGCCGCACTGTCCCGAGTGCGGCCGTCCCATCTCGCGCCAGTCGCCGC
AGGCCATCGTGGACAAGGTCCTCGGCCTGCCCGAGGGCAGCCGCTTCCAGGTGCTCTCGCCGCTCGTGCGCGAGCGCAAG
GGCGAGTTCGTCGACCTCTTCGCCGACCTGCAGACCAAGGGATACAGCAGGGCCAGGGTCGACGGCGCGACCATCCAGCT
CTCCGAGCCGCCCACGCTCAAGAAGCAGGAGAAGCACACCATCGAGGTGGTCATCGACCGCCTCACGGTGAAGGACAGCG
CCAAGCGCCGGCTGACCGACTCGGTCGAGACCGCGCTGGGCCTCTCCGGCGGCATGGTCGTGCTCGACTTCGTCGACCTC
CCCGAGGACGACCCCGAGCGTGAGCGGATGTACTCCGAGCACCTCTACTGCCCGTACGACGACCTCTCCTTCGAGGAGCT
GGAGCCGCGCTCCTTCTCCTTCAACTCCCCCTTCGGCGCCTGCCCCGACTGCACGGGCATCGGCACGCGGATGGAGGTCG
ACCCGGAGCTGATCGTCCCGGACGAGGAGAAGTCCCTCGACGAGGGCGCGATCCACCCCTGGTCGCACGGCCACACCAAG
GAGTACTTCGGCCGCCAGATCAACGCCCTGGCCGAAGCCCTCGGATTCCGTACGGACATCCCCTGGGCCGGGCTCCCGCA
GCGCGCCAAGAAGGCCCTGCTCTTCGGTCACAAGATCCAGACCGAGGTCCGCTACCGCAACCGGTACGGGCGCGAGCGCG
CCTACACCACGCCCTCCTTCGAAGGCGCGGTGCAGTTCGTCAAGAGGCGGCACTCCGAGGCGGAGAGCGACTCCAGCCGG
GAACGCTTCGAGGGCTATATGCGCGAGGTGCCCTGCCCGACCTGTGAGGGCACCCGGCTCAAGCCGATCGTCCTCGCGGT
CACGGTGATGGAGAAGTCCATCGCACAGGTCGCCGCGATGTCGATCAGCGAGTGCGCCGAGTTCCTCGGCCGCATGAAGC
TGAACGCCCGCGACAAGAAGATCGCCGAGCGGGTGCTCAAGGAGGTCAACGAGCGGCTGAAGTTCCTGGTCGACGTCGGC
CTGGACTACCTCTCGCTGAACCGCGCGGCGGGCACCCTGTCCGGCGGCGAGGCCCAGCGCATCCGGCTCGCCACCCAGAT
CGGCTCCGGCCTGGTCGGCGTGCTGTACGTGCTGGACGAGCCGTCCATCGGGCTGCACCAGCGTGACAACCACCGGCTGA
TCGAGACCCTGGTCCGGCTCCGCGACATGGGCAACACGCTCATCGTCGTCGAGCACGACGAGGACACGATCAAGGTCGCC
GACTGGGTCGTCGACATCGGCCCCGGCGCCGGCGAGCACGGCGGCAAGGTGGTCCACTCCGGATCGCTCAAGGAACTGCT
GGCCAACGACAAGTCGATCACCGGTCAGTACCTGACCGGCAAGAGGTCGATCGCGATGCCCGAGATCCGGCGTCCCGTCG
ACCCCTCGCGCCTGCTCACGGTCCACGGCGCCCGGGAGAACAACCTCCAGGACATCGACGTCGCCTTCCCGCTCGGCGTG
CTGACCGCCGTGACCGGCGTCTCCGGCTCCGGGAAGTCGACCCTGGTCAACGACATCCTCTACACCCACCTGGCCCGCGA
GCTGAACGGCGCCAAGTCGGTGCCCGGCCGGCACACCCGGGTCGACGGGGACGACCTCGTCGACAAGGTGGTGCACGTCG
ACCAGTCGCCCATCGGCCGGACACCCCGGTCCAACCCGGCGACGTACACGGGCGTCTTCGACCACGTCCGCCGGCTGTTC
GCGGAGACGATGGAGGCCAAGGTCCGCGGCTATCTGCCGGGCCGGTTCTCCTTCAACGTGAAGGGCGGCCGCTGCGAGAA
CTGCTCCGGCGACGGCACCATCAAGATCGAGATGAACTTCCTGCCCGACGTGTACGTCCCGTGCGAGGTCTGCCACGGAG
CGCGCTACAACCGGGAGACCCTTGAGGTCCACTACAAGGGCAAGTCCATCGCCGAGGTGCTGGACATGCCGATCGAGGAG
GGCCTGGAGTTCTTCGAGGCCGTCCCGACCATCGCGCGTCACCTGCGGACGCTCAACGAGGTCGGTCTCGGATACGTCAG
GCTCGGCCAGTCCGCGCCGACACTCTCCGGCGGTGAGGCGCAGCGGGTGAAGCTCGCCAGCGAGCTCCAGAAGCGCTCCA
CCGGACGCACGGTCTACGTCCTGGACGAGCCGACCACCGGTCTGCACTTCGAGGACATCTCCAAGCTGATCAAGGTGCTC
TCCGGCCTGGTCGACAAGGGCAACTCGGTGATCGTCATCGAGCACAACCTCGATGTCATCAAGACCGCCGACTGGGTCAT
CGACATGGGACCCGAGGGGGGCAACGGCGGCGGTCTGGTCATCGCCGAGGGCACCCCGGAGTTCGTGGCGGGCGTCCCCG
CCAGCCACACCGGTAAGTTCCTCCAGGGCATCCTGGACGCGGACCGGGTCAGCGAGGCGGCCGTGCCCGCGGCGCGCAAG
CCGGTGCGGAAGACGGCCGCGAAGAAGGCGGTGGCAGCGAAGTCCGCCCCCGCGCGGAAGACGGCGACGGCGAAGACCCC
GGCCAAGAAGGCCACGGCGAAGTCCACCGGGACGGCAGCGGCGAAGAAGCCCGCGGCCAAGAAGGCGCCCCGCGCGCGCA
AGGCCTGA

Domains

Predicted by InterProScan.

UvrA interaction domain (UvrA_inter)

(131-238)

UvrA DNA-binding domain (UvrA_DNA-bind)

(294-404)

ABC transporter (ABC_tran)

(629-865)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrA Streptococcus pneumoniae R6

56.375

93.498

0.527
  uvrA Streptococcus pneumoniae TIGR4

56.375

93.498

0.527
  uvrA Streptococcus pneumoniae D39

56.375

93.498

0.527