Detailed information NTG0662388

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: MNU36_RS04790
• Genome accession: NZ_CP093198
• Coordinates: 993555..994601 (+)
• Length: 348 a.a.
• NCBI ID: WP_001830374.1
• Uniprot ID: A0A0N1EGU4
• Organism: Staphylococcus epidermidis strain TSM-18
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 988555..999601

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MNU36_RS04765 (MNU36_04765)	-	989696..990232 (+)	537	WP_002470337.1	hypothetical protein	-
MNU36_RS04770 (MNU36_04770)	-	990383..991369 (-)	987	WP_001830388.1	aromatic acid exporter family protein	-
MNU36_RS04775 (MNU36_04775)	map	991543..992298 (+)	756	WP_002457092.1	type I methionyl aminopeptidase	-
MNU36_RS04780 (MNU36_04780)	-	992456..992842 (+)	387	WP_001830382.1	hypothetical protein	-
MNU36_RS04785 (MNU36_04785)	liaF	992857..993558 (+)	702	WP_001830436.1	cell wall-active antibiotics response protein LiaF	-
MNU36_RS04790 (MNU36_04790)	vraS	993555..994601 (+)	1047	WP_001830374.1	sensor histidine kinase	Regulator
MNU36_RS04795 (MNU36_04795)	vraR	994591..995220 (+)	630	WP_001830439.1	two-component system response regulator VraR	Regulator
MNU36_RS04800 (MNU36_04800)	-	995277..996455 (-)	1179	WP_001830411.1	YihY/virulence factor BrkB family protein	-
MNU36_RS04805 (MNU36_04805)	-	996862..997146 (-)	285	WP_001830401.1	YtxH domain-containing protein	-
MNU36_RS04810 (MNU36_04810)	-	997154..997618 (-)	465	WP_001830437.1	low molecular weight protein-tyrosine-phosphatase	-
MNU36_RS04815 (MNU36_04815)	-	997759..997974 (+)	216	WP_001830421.1	DUF1128 domain-containing protein	-
MNU36_RS04820 (MNU36_04820)	-	997976..999217 (+)	1242	WP_001832467.1	aminopeptidase	-

Sequence

Protein

• Length: 348 a.a.
• Molecular weight: 40066.49 Da
• Isoelectric Point: 5.8512

>NTDB_id=662388 MNU36_RS04790 WP_001830374.1 993555..994601(+) (vraS) [Staphylococcus epidermidis strain TSM-18]
MNHYIRAIGSMLILVYSMLIAFLFIDKVFVNIIFFQGMFYTQIFGIPVFLFLNLLIVLLCIIVGSVLAYKINQQNDWIIS
QIERSIEGQTVGINDQNIELYTETIDIYHTLVPLNQELHRLRMKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKESKLEPPLNQQIPILEKMVQDSQLEMRALLLHLRPIGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFEVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNQEDYLLLRIQDNGKGFNVDEKFEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEENSSGD

Nucleotide

• Length: 1047 bp

>NTDB_id=662388 MNU36_RS04790 WP_001830374.1 993555..994601(+) (vraS) [Staphylococcus epidermidis strain TSM-18]
ATGAATCACTACATAAGAGCTATAGGCTCAATGCTTATATTAGTATATAGTATGCTTATTGCTTTTTTATTTATTGATAA
AGTGTTTGTAAATATTATCTTTTTTCAGGGGATGTTTTATACACAAATATTTGGAATACCTGTTTTTCTATTTTTAAATT
TATTAATTGTTCTTTTATGTATTATAGTTGGATCTGTTTTAGCTTATAAAATTAATCAACAAAATGATTGGATTATTTCA
CAAATAGAAAGATCAATAGAAGGACAAACAGTAGGTATCAATGATCAAAATATCGAATTATATACAGAAACGATAGATAT
TTATCATACACTAGTTCCATTAAATCAAGAATTACATCGACTTAGAATGAAGACTCAAAATTTAACTAATGAAAACTACA
ATATTAATGATGTAAAAGTCAAAAAGATTATCGAAGATGAGCGACAACGACTTGCCAGGGAATTACATGATTCTGTTAGT
CAACAATTATTTGCTGCGAGCATGATGCTATCGGCGATAAAAGAGTCGAAATTAGAACCACCTTTAAATCAACAGATACC
AATTCTTGAAAAAATGGTTCAAGACTCACAACTTGAAATGAGAGCTTTGTTATTACATTTAAGACCGATAGGTTTAAAAG
ATAAGTCTTTAGGTGAAGGAATTAAAGATTTAGTCATCGATTTACAAAAGAAAGTACCAATGAAAGTTGTGCATGAAATT
CAAGATTTTGAAGTGCCAAAAGGCATTGAAGATCACTTGTTCAGAATTACACAAGAAGCTATTTCAAATACATTGAGACA
TTCAAATGGTACAAAAGTAACTGTGGAATTATTTAATCAAGAGGATTATCTTTTACTAAGAATTCAAGATAATGGAAAAG
GGTTTAATGTAGATGAAAAATTTGAACAAAGTTATGGTTTGAAAAATATGCGAGAACGAGCGTTAGAAATTGGTGCGACG
TTTCATATTGTATCTTTACCTGATTCAGGTACACGAATTGAAGTTAAGGCACCATTGAATAAGGAGGAGAATTCAAGTGG
CGATTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0N1EGU4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	93.023	98.851	0.92