Detailed information NTG0662101

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: MNU35_RS04765
• Genome accession: NZ_CP093170
• Coordinates: 1010227..1011273 (+)
• Length: 348 a.a.
• NCBI ID: WP_002447441.1
• Uniprot ID: -
• Organism: Staphylococcus epidermidis strain TMDU-128
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1005227..1016273

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MNU35_RS04740 (MNU35_04745)	-	1006367..1006903 (+)	537	WP_002447446.1	hypothetical protein	-
MNU35_RS04745 (MNU35_04750)	-	1007055..1008041 (-)	987	WP_002447445.1	aromatic acid exporter family protein	-
MNU35_RS04750 (MNU35_04755)	map	1008215..1008970 (+)	756	WP_002447444.1	type I methionyl aminopeptidase	-
MNU35_RS04755 (MNU35_04760)	-	1009128..1009514 (+)	387	WP_002495657.1	hypothetical protein	-
MNU35_RS04760 (MNU35_04765)	liaF	1009529..1010230 (+)	702	WP_002447442.1	cell wall-active antibiotics response protein LiaF	-
MNU35_RS04765 (MNU35_04770)	vraS	1010227..1011273 (+)	1047	WP_002447441.1	sensor histidine kinase	Regulator
MNU35_RS04770 (MNU35_04775)	vraR	1011263..1011892 (+)	630	WP_002473914.1	two-component system response regulator VraR	Regulator
MNU35_RS04775 (MNU35_04780)	-	1011949..1013127 (-)	1179	WP_002487362.1	YihY/virulence factor BrkB family protein	-
MNU35_RS04780 (MNU35_04785)	-	1013533..1013817 (-)	285	WP_002447438.1	YtxH domain-containing protein	-
MNU35_RS04785 (MNU35_04790)	-	1013825..1014289 (-)	465	WP_001830437.1	low molecular weight protein-tyrosine-phosphatase	-
MNU35_RS04790 (MNU35_04795)	-	1014431..1014646 (+)	216	WP_001830421.1	DUF1128 domain-containing protein	-
MNU35_RS04795 (MNU35_04800)	-	1014648..1015889 (+)	1242	WP_254106354.1	aminopeptidase	-

Sequence

Protein

• Length: 348 a.a.
• Molecular weight: 40114.53 Da
• Isoelectric Point: 5.8512

>NTDB_id=662101 MNU35_RS04765 WP_002447441.1 1010227..1011273(+) (vraS) [Staphylococcus epidermidis strain TMDU-128]
MNHYIRAIGSMLILVYSMLIAFLFIDKVFVNIIFFQGMFYTQIFGIPVFLFLNLLIVFLCIIVGSVLAYKINQQNDWIIS
QIERSIEGQTVGINDQNIELYTETIDIYHTLVPLNQELHRLRMKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKESKLEPPLNQQIPILEKMVQDSQLEMRALLLHLRPIGLKDKSLGEGIKDLVIDLQKKVPMKVLHEI
QDFEVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNQEDYLLLRIQDNGKGFNVDEKFEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEENSSGD

Nucleotide

• Length: 1047 bp

>NTDB_id=662101 MNU35_RS04765 WP_002447441.1 1010227..1011273(+) (vraS) [Staphylococcus epidermidis strain TMDU-128]
ATGAATCACTACATAAGAGCTATAGGCTCAATGCTTATATTAGTATATAGTATGCTTATTGCTTTTTTATTTATTGATAA
AGTGTTTGTAAATATTATCTTTTTTCAAGGGATGTTTTATACACAAATATTTGGAATACCTGTTTTTCTATTTTTAAATT
TATTAATTGTTTTTTTATGTATTATAGTTGGATCTGTTTTAGCTTATAAAATTAATCAACAAAATGATTGGATTATTTCC
CAAATAGAAAGATCAATAGAAGGACAAACAGTAGGTATCAATGATCAAAATATCGAATTATATACAGAAACGATAGATAT
TTATCATACACTAGTTCCATTAAATCAAGAATTACATCGACTTAGAATGAAGACTCAGAATTTAACTAATGAAAACTACA
ATATTAATGATGTAAAAGTCAAAAAGATTATCGAAGATGAGCGACAACGACTTGCAAGGGAATTGCATGATTCTGTTAGC
CAACAATTATTTGCTGCGAGCATGATGCTATCGGCAATAAAAGAGTCGAAATTAGAACCACCTTTAAATCAACAGATACC
AATTCTTGAAAAAATGGTTCAAGACTCACAACTTGAAATGAGAGCTTTGTTGTTACATTTAAGACCGATAGGTTTAAAAG
ATAAGTCTCTAGGTGAAGGTATTAAAGATTTAGTCATCGATTTACAAAAGAAAGTACCAATGAAAGTTTTGCATGAAATT
CAAGATTTTGAAGTGCCAAAAGGTATTGAAGATCATTTGTTCAGAATTACACAAGAAGCTATTTCAAATACATTGAGACA
TTCAAATGGTACGAAAGTAACTGTGGAATTATTTAATCAAGAGGATTATCTTTTACTAAGAATTCAAGATAATGGAAAAG
GATTTAATGTAGATGAAAAATTTGAACAAAGTTATGGTTTAAAAAATATGCGAGAACGAGCGTTAGAAATTGGTGCGACG
TTTCATATTGTATCTTTACCTGATTCAGGTACACGAATTGAAGTTAAGGCACCATTGAATAAGGAGGAGAACTCAAGTGG
CGATTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	92.442	98.851	0.914