Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OG251_RS29680 Genome accession   NZ_CP108508
Coordinates   6638080..6638814 (-) Length   244 a.a.
NCBI ID   WP_326679968.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_01237     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 6633080..6643814
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OG251_RS29660 (OG251_29670) - 6633275..6634711 (+) 1437 WP_073726796.1 gamma-aminobutyraldehyde dehydrogenase -
  OG251_RS29665 (OG251_29675) - 6634910..6636073 (+) 1164 WP_326681464.1 spermidine/putrescine ABC transporter substrate-binding protein -
  OG251_RS29670 (OG251_29680) - 6636125..6636706 (+) 582 WP_326679966.1 hypothetical protein -
  OG251_RS29675 (OG251_29685) - 6636779..6638005 (-) 1227 WP_326679967.1 serine hydrolase domain-containing protein -
  OG251_RS29680 (OG251_29690) vraR 6638080..6638814 (-) 735 WP_326679968.1 response regulator transcription factor Regulator
  OG251_RS29685 (OG251_29695) - 6638811..6640079 (-) 1269 WP_326679969.1 histidine kinase -
  OG251_RS29690 (OG251_29700) - 6640079..6640885 (-) 807 WP_326679970.1 SAM-dependent methyltransferase -
  OG251_RS29695 (OG251_29705) - 6640953..6641675 (-) 723 WP_326679971.1 glycerophosphodiester phosphodiesterase -
  OG251_RS29700 (OG251_29710) - 6641698..6642732 (-) 1035 WP_326679972.1 adenosine deaminase -
  OG251_RS29705 (OG251_29715) - 6642855..6643583 (+) 729 WP_326679973.1 DUF4190 domain-containing protein -

Sequence

Protein


Download         Length: 244 a.a.        Molecular weight: 26207.90 Da        Isoelectric Point: 5.6533

>NTDB_id=661844 OG251_RS29680 WP_326679968.1 6638080..6638814(-) (vraR) [Streptomyces sp. NBC_01237]
MTIRVVVADDQELVRSGFAMILDAQPDIEVVAEAGDGERTLDAVRRLRPDVALLDIRMPVMDGIEACRAISAQSACRTVM
LTTFDADEYVYESLHAGASGFLLKDVRRDDLVHAVRVVSAGDSLLAPSVARRLIAEYTARPPATASAAPSAQRLEVLTAR
ERETLLHLARGLSNAEIAAALVVSEHTVKTHVGNVLSKLGLRDRIQAVICAYETGLVAPSPEGEAALSSPAQARRSRGED
HPLR

Nucleotide


Download         Length: 735 bp        

>NTDB_id=661844 OG251_RS29680 WP_326679968.1 6638080..6638814(-) (vraR) [Streptomyces sp. NBC_01237]
TTGACGATCCGCGTGGTGGTGGCCGACGACCAGGAGCTGGTGCGCAGCGGATTCGCGATGATCCTGGACGCGCAGCCGGA
CATCGAGGTGGTCGCGGAGGCCGGTGACGGTGAGCGGACTCTCGACGCGGTGCGGCGGCTGCGGCCCGACGTGGCGCTGC
TGGACATCCGGATGCCCGTCATGGACGGCATCGAGGCGTGCCGGGCGATCAGCGCGCAGAGCGCGTGCCGGACGGTCATG
CTGACCACGTTCGACGCGGACGAGTATGTCTATGAGTCCCTGCACGCGGGCGCGAGCGGCTTTCTGCTGAAGGACGTCCG
CCGGGACGACCTGGTGCACGCGGTGCGGGTGGTGTCGGCCGGTGACTCGCTGCTGGCCCCGTCGGTGGCGCGCCGGCTGA
TCGCCGAGTACACCGCCCGACCGCCCGCGACCGCCTCCGCCGCACCGTCCGCGCAGCGGCTGGAGGTGCTGACCGCCCGG
GAGCGGGAGACCCTGCTGCATCTGGCCCGCGGTCTGTCCAACGCGGAGATAGCGGCCGCGCTCGTGGTCAGCGAGCACAC
GGTGAAGACGCATGTGGGCAACGTGCTGTCCAAGCTGGGCCTGCGGGACCGGATCCAGGCGGTCATCTGCGCGTACGAGA
CGGGGCTCGTCGCTCCCTCGCCGGAGGGAGAGGCCGCGCTCTCCTCCCCCGCACAGGCGAGGAGATCACGGGGCGAGGAC
CACCCGCTCCGGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(5-116)

Bacterial regulatory proteins, luxR family (GerE)

(156-211)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

40.826

89.344

0.365