Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OG564_RS22615 Genome accession   NZ_CP108438
Coordinates   5018200..5018868 (-) Length   222 a.a.
NCBI ID   WP_266672677.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_01280     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 5013200..5023868
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OG564_RS22595 (OG564_22590) - 5014192..5015013 (+) 822 WP_329434458.1 diacylglycerol kinase -
  OG564_RS22600 (OG564_22595) - 5015022..5016638 (-) 1617 WP_329434460.1 ABC transporter permease -
  OG564_RS22605 (OG564_22600) - 5016635..5017573 (-) 939 WP_329434461.1 ABC transporter ATP-binding protein -
  OG564_RS22610 (OG564_22605) - 5017762..5018193 (+) 432 WP_266676504.1 MarR family transcriptional regulator -
  OG564_RS22615 (OG564_22610) vraR 5018200..5018868 (-) 669 WP_266672677.1 response regulator transcription factor Regulator
  OG564_RS22620 (OG564_22615) - 5018935..5020281 (-) 1347 WP_329437795.1 histidine kinase -
  OG564_RS22625 (OG564_22620) - 5020415..5021287 (-) 873 WP_266672675.1 alpha/beta hydrolase -
  OG564_RS22630 (OG564_22625) - 5021409..5022059 (+) 651 WP_329434462.1 TetR/AcrR family transcriptional regulator -
  OG564_RS22635 (OG564_22630) kynU 5022067..5023287 (-) 1221 WP_329434463.1 kynureninase -

Sequence

Protein


Download         Length: 222 a.a.        Molecular weight: 24154.00 Da        Isoelectric Point: 4.6799

>NTDB_id=660589 OG564_RS22615 WP_266672677.1 5018200..5018868(-) (vraR) [Streptomyces sp. NBC_01280]
MTIRVLIADDQMMVREGFSVLLNAMPDIEVVGEAVNGREAIARVRELSPDVVLMDIRMPELNGIEATREIAAMDGSAKVL
VLTTFDLDEYVYQALRAGASGFLLKDASARQLADGVRVVAQGEALLAPSVTRRLITEFSKLSEIPKLPAVANPEAFGELT
ERETEVLVLIAQGLSNAEIAERLVVAESTIKTHVSRVLVKLGLRDRTQAAVFAYEARLVRPA

Nucleotide


Download         Length: 669 bp        

>NTDB_id=660589 OG564_RS22615 WP_266672677.1 5018200..5018868(-) (vraR) [Streptomyces sp. NBC_01280]
ATGACCATCCGCGTACTGATCGCCGACGACCAGATGATGGTCCGTGAGGGCTTCTCGGTGCTGCTCAACGCGATGCCCGA
CATCGAGGTCGTCGGCGAGGCGGTCAACGGCCGGGAGGCGATCGCCCGGGTCCGTGAACTCTCCCCGGACGTCGTCCTCA
TGGACATCCGCATGCCGGAGCTGAACGGCATCGAGGCCACCCGCGAGATCGCCGCGATGGACGGCAGCGCGAAGGTGCTC
GTCCTGACCACCTTCGACCTCGACGAGTACGTCTACCAGGCCCTGCGCGCCGGTGCCTCCGGCTTCCTCCTCAAGGACGC
CTCGGCCCGCCAACTGGCCGACGGTGTAAGGGTGGTGGCCCAGGGCGAGGCGCTCCTCGCCCCCTCGGTCACCCGCCGCC
TGATCACGGAGTTCTCCAAGTTGTCCGAGATCCCGAAGCTGCCGGCGGTGGCGAACCCGGAGGCGTTCGGTGAGCTGACG
GAGCGCGAGACGGAGGTGCTGGTCCTGATCGCCCAGGGCCTGTCGAACGCGGAGATCGCCGAACGGCTGGTCGTCGCCGA
GTCGACCATCAAGACCCACGTCAGCCGGGTCCTGGTGAAGCTGGGCCTGCGCGACCGCACCCAGGCGGCGGTGTTCGCGT
ACGAGGCCCGGCTGGTCAGGCCCGCGTAG

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(5-114)

Bacterial regulatory proteins, luxR family (GerE)

(159-213)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

44.091

99.099

0.437
  degU Bacillus subtilis subsp. subtilis str. 168

41.743

98.198

0.41