Detailed information NTG0660512

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: MK796_RS09710
• Genome accession: NZ_CP092825
• Coordinates: 1974902..1975945 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain GY8
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1969902..1980945

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MK796_RS09680 (MK796_09680)	-	1970323..1971579 (-)	1257	WP_078065149.1	aminopeptidase	-
MK796_RS09685 (MK796_09685)	-	1971582..1971782 (-)	201	WP_000180460.1	DUF1128 family protein	-
MK796_RS09690 (MK796_09690)	-	1971929..1972393 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
MK796_RS09695 (MK796_09695)	-	1972400..1972675 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
MK796_RS09700 (MK796_09700)	-	1972953..1974170 (+)	1218	WP_000037087.1	YihY/virulence factor BrkB family protein	-
MK796_RS09705 (MK796_09705)	vraR	1974283..1974912 (-)	630	WP_000153526.1	two-component system response regulator VraR	Regulator
MK796_RS09710 (MK796_09710)	vraS	1974902..1975945 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
MK796_RS09715 (MK796_09715)	liaF	1975942..1976643 (-)	702	WP_000149062.1	cell wall-active antibiotics response protein LiaF	-
MK796_RS09720 (MK796_09720)	-	1976658..1977044 (-)	387	WP_001110179.1	hypothetical protein	-
MK796_RS09725 (MK796_09725)	map	1977261..1978019 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
MK796_RS09730 (MK796_09730)	-	1978548..1979534 (+)	987	WP_000999708.1	aromatic acid exporter family protein	-
MK796_RS09735 (MK796_09735)	-	1979967..1980380 (-)	414	WP_025174552.1	hypothetical protein	-
MK796_RS09740 (MK796_09740)	-	1980409..1980519 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=660512 MK796_RS09710 WP_001017131.1 1974902..1975945(-) (vraS) [Staphylococcus aureus strain GY8]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=660512 MK796_RS09710 WP_001017131.1 1974902..1975945(-) (vraS) [Staphylococcus aureus strain GY8]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGTATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAACGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGATCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1