Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   MK616_RS05845 Genome accession   NZ_CP092778
Coordinates   1140007..1140663 (+) Length   218 a.a.
NCBI ID   WP_003155032.1    Uniprot ID   I2C3J8
Organism   Bacillus amyloliquefaciens strain WF2020     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 1135007..1145663
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MK616_RS05820 (MK616_05820) oppF 1135557..1136474 (+) 918 WP_110124643.1 oligopeptide ABC transporter ATP-binding protein OppF -
  MK616_RS05825 (MK616_05825) - 1136581..1137750 (+) 1170 WP_100261694.1 putative glycoside hydrolase -
  MK616_RS05830 (MK616_05830) - 1137868..1138446 (+) 579 WP_007409110.1 GNAT family N-acetyltransferase -
  MK616_RS05835 (MK616_05835) spx 1138625..1139020 (+) 396 WP_003155034.1 transcriptional regulator Spx -
  MK616_RS05840 (MK616_05840) - 1139075..1139731 (-) 657 WP_014417421.1 TerC family protein -
  MK616_RS05845 (MK616_05845) mecA 1140007..1140663 (+) 657 WP_003155032.1 adaptor protein MecA Regulator
  MK616_RS05850 (MK616_05850) - 1140815..1141975 (+) 1161 WP_110124644.1 competence protein CoiA family protein -
  MK616_RS05855 (MK616_05855) pepF 1142203..1144032 (+) 1830 WP_003155028.1 oligoendopeptidase F Regulator
  MK616_RS05860 (MK616_05860) - 1144070..1144237 (-) 168 WP_003155026.1 hypothetical protein -
  MK616_RS05865 (MK616_05865) spxH 1144523..1145425 (-) 903 WP_003155024.1 protease adaptor protein SpxH -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 25964.75 Da        Isoelectric Point: 4.1143

>NTDB_id=660188 MK616_RS05845 WP_003155032.1 1140007..1140663(+) (mecA) [Bacillus amyloliquefaciens strain WF2020]
MEIERINEHTVKFYMSYGDIEDRGFDREEIWYNRERSEELFWEVMDEVHDEEEFAVEGPLWIQVQALDKGLEIIVTKAQL
SKDGQKLELPIPEDKKQEPADENLDALLDDFQKEEQAESREDKEQKLQFTLRFDDFEDLISLSKLNLNGIKTTLYSFEDR
YYLYADFYEQTDEEVENQLSILLEYAHESSVSIHRLEEYGKLVIADHALYTIKKHFAS

Nucleotide


Download         Length: 657 bp        

>NTDB_id=660188 MK616_RS05845 WP_003155032.1 1140007..1140663(+) (mecA) [Bacillus amyloliquefaciens strain WF2020]
ATGGAAATAGAAAGAATTAATGAGCATACTGTAAAATTTTATATGTCTTATGGTGATATTGAAGATCGCGGTTTTGACAG
AGAAGAAATCTGGTACAATCGCGAGCGCAGTGAAGAACTGTTCTGGGAAGTCATGGATGAAGTGCATGATGAAGAAGAAT
TCGCTGTCGAGGGTCCTCTTTGGATTCAGGTTCAGGCATTGGACAAAGGACTGGAAATAATCGTAACAAAAGCCCAGCTT
TCCAAGGACGGACAAAAACTCGAACTGCCGATCCCGGAAGATAAAAAACAAGAGCCGGCAGATGAAAATCTCGATGCTTT
ACTTGATGATTTCCAGAAAGAAGAGCAGGCCGAGAGCCGGGAAGATAAGGAGCAAAAGCTTCAGTTCACTTTGCGGTTCG
ATGATTTTGAGGATCTCATCTCGCTATCAAAATTGAATCTTAACGGAATCAAAACGACCCTGTATTCGTTTGAAGACCGA
TATTATTTATATGCAGATTTTTATGAGCAAACTGATGAAGAGGTTGAAAATCAGCTAAGCATCCTGTTGGAGTACGCGCA
CGAATCATCAGTCAGCATTCACCGTCTTGAAGAATACGGCAAATTGGTGATCGCTGATCATGCGTTATATACAATAAAAA
AACACTTTGCATCATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB I2C3J8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

89.45

100

0.895