Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   MKF36_RS05585 Genome accession   NZ_CP092750
Coordinates   1073462..1074118 (+) Length   218 a.a.
NCBI ID   WP_003155032.1    Uniprot ID   I2C3J8
Organism   Bacillus velezensis strain KS04AU     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 1068462..1079118
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MKF36_RS05555 (MKF36_05555) oppF 1068991..1069908 (+) 918 WP_020955632.1 oligopeptide ABC transporter ATP-binding protein OppF -
  MKF36_RS05560 (MKF36_05560) - 1070015..1071202 (+) 1188 WP_042635052.1 putative glycoside hydrolase -
  MKF36_RS05565 (MKF36_05565) - 1071320..1071898 (+) 579 WP_007409110.1 GNAT family N-acetyltransferase -
  MKF36_RS05570 (MKF36_05570) spx 1072077..1072472 (+) 396 WP_003155034.1 transcriptional regulator Spx -
  MKF36_RS05575 (MKF36_05575) - 1072530..1073186 (-) 657 WP_007409109.1 TerC family protein -
  MKF36_RS05580 (MKF36_05580) - 1073369..1073479 (+) 111 Protein_1094 adaptor protein MecA -
  MKF36_RS05585 (MKF36_05585) mecA 1073462..1074118 (+) 657 WP_003155032.1 adaptor protein MecA Regulator
  MKF36_RS05590 (MKF36_05590) - 1074269..1075429 (+) 1161 WP_042635053.1 competence protein CoiA family protein -
  MKF36_RS05595 (MKF36_05595) pepF 1075657..1077486 (+) 1830 WP_007409107.1 oligoendopeptidase F Regulator
  MKF36_RS05600 (MKF36_05600) - 1077524..1077691 (-) 168 WP_003155026.1 hypothetical protein -
  MKF36_RS05605 (MKF36_05605) spxH 1077977..1078879 (-) 903 WP_015239573.1 protease adaptor protein SpxH -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 25964.75 Da        Isoelectric Point: 4.1143

>NTDB_id=660011 MKF36_RS05585 WP_003155032.1 1073462..1074118(+) (mecA) [Bacillus velezensis strain KS04AU]
MEIERINEHTVKFYMSYGDIEDRGFDREEIWYNRERSEELFWEVMDEVHDEEEFAVEGPLWIQVQALDKGLEIIVTKAQL
SKDGQKLELPIPEDKKQEPADENLDALLDDFQKEEQAESREDKEQKLQFTLRFDDFEDLISLSKLNLNGIKTTLYSFEDR
YYLYADFYEQTDEEVENQLSILLEYAHESSVSIHRLEEYGKLVIADHALYTIKKHFAS

Nucleotide


Download         Length: 657 bp        

>NTDB_id=660011 MKF36_RS05585 WP_003155032.1 1073462..1074118(+) (mecA) [Bacillus velezensis strain KS04AU]
ATGGAAATAGAAAGAATTAATGAGCATACTGTAAAATTTTATATGTCTTATGGTGATATTGAAGATCGCGGTTTTGACAG
AGAAGAAATCTGGTACAATCGCGAGCGCAGTGAAGAACTGTTCTGGGAAGTCATGGATGAAGTGCATGATGAAGAGGAAT
TCGCTGTCGAGGGTCCTCTTTGGATTCAGGTTCAGGCATTGGACAAAGGACTGGAAATAATCGTAACAAAAGCCCAGCTT
TCCAAGGACGGACAAAAACTCGAACTGCCGATCCCGGAAGATAAAAAACAAGAGCCGGCAGATGAAAATCTCGATGCTTT
ACTTGATGATTTCCAGAAAGAAGAGCAGGCCGAGAGCCGGGAAGATAAGGAGCAAAAGCTTCAGTTCACTTTGCGGTTCG
ATGATTTTGAGGATCTCATCTCGCTATCAAAATTGAATCTTAACGGAATCAAAACGACCCTGTATTCGTTTGAAGACCGA
TATTATTTATATGCAGATTTTTATGAGCAAACTGATGAAGAGGTTGAAAATCAGCTAAGCATCCTGTTGGAGTACGCGCA
CGAATCATCAGTCAGCATTCACCGTCTTGAAGAATACGGCAAATTGGTGATCGCTGATCATGCGTTATATACAATAAAAA
AACACTTTGCATCATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB I2C3J8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

89.45

100

0.895