Detailed information    

insolico Bioinformatically predicted

Overview

Name   irvR   Type   Regulator
Locus tag   SMUNUM_RS06520 Genome accession   NZ_AP014571
Coordinates   1333298..1334191 (+) Length   297 a.a.
NCBI ID   WP_002262721.1    Uniprot ID   A0A090B2L0
Organism   Streptococcus mutans LP13     
Function   regulate expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1328298..1339191
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SMUNUM_RS06500 (SMNUM_1240) - 1330262..1330390 (-) 129 WP_002262718.1 hypothetical protein -
  SMUNUM_RS06505 - 1330425..1330655 (-) 231 WP_002282891.1 hypothetical protein -
  SMUNUM_RS06510 (SMNUM_1242) - 1330785..1332536 (-) 1752 WP_019805441.1 GbpC/Spa domain-containing protein -
  SMUNUM_RS06515 (SMNUM_1243) - 1332699..1332983 (-) 285 WP_002262720.1 helix-turn-helix transcriptional regulator -
  SMUNUM_RS06520 (SMNUM_1244) irvR 1333298..1334191 (+) 894 WP_002262721.1 LexA family transcriptional regulator IrvR Regulator
  SMUNUM_RS06525 (SMNUM_1246) csn2-St 1335393..1336442 (-) 1050 WP_002296723.1 CRISPR-associated protein Csn2-St -
  SMUNUM_RS06530 (SMNUM_1247) cas2 1336439..1336762 (-) 324 WP_002287011.1 CRISPR-associated endonuclease Cas2 -
  SMUNUM_RS06535 (SMNUM_1248) cas1 1336765..1337673 (-) 909 WP_002287010.1 type II CRISPR-associated endonuclease Cas1 -

Sequence

Protein


Download         Length: 297 a.a.        Molecular weight: 33651.40 Da        Isoelectric Point: 6.7038

>NTDB_id=65981 SMUNUM_RS06520 WP_002262721.1 1333298..1334191(+) (irvR) [Streptococcus mutans LP13]
MGRGKLTPQDLEAMKAISANLQRLLAESGMKQSHLATILNIPTSSLNEYVKGKSLPKIGNIQKIADYFGLQKSDIDPRFA
SKKDSSTLDKINHIAKQLEMKRQIKVLDFCYQQSKEQDETASLSASDETTEDKVADKSNHTQYQKVVDSFIAKELNDQTI
IHWDNVIKAKDLYQTFGRQYENIQIYGEVSAGTGIWVGHEKQETIKYPIPIPEHDIALIVNGNSMEPLFYNGDVIFVKKT
KAIHHGQIIVVIVNNEAYVKKLYRKNKEIRLISLNPDYDDIILKEDDTIEVIGTVIT

Nucleotide


Download         Length: 894 bp        

>NTDB_id=65981 SMUNUM_RS06520 WP_002262721.1 1333298..1334191(+) (irvR) [Streptococcus mutans LP13]
ATGGGACGCGGTAAATTAACTCCACAAGATTTAGAAGCAATGAAGGCTATTTCTGCCAATCTTCAAAGACTTCTAGCTGA
GAGCGGAATGAAACAATCTCACTTAGCTACTATTCTTAACATTCCTACAAGTAGTCTTAACGAATATGTTAAGGGAAAGA
GTTTGCCAAAAATAGGGAATATTCAAAAAATCGCAGATTACTTTGGTTTACAAAAATCCGATATTGACCCTAGATTTGCA
AGTAAAAAGGACTCTTCTACTCTTGATAAAATTAATCATATTGCCAAACAATTAGAAATGAAGAGACAGATAAAAGTCTT
AGATTTCTGTTACCAACAATCAAAAGAACAAGATGAAACAGCAAGCTTGTCTGCCAGTGATGAAACGACTGAGGATAAAG
TTGCTGACAAATCAAATCATACGCAGTATCAAAAGGTTGTTGATTCTTTTATTGCCAAAGAATTAAACGATCAGACAATT
ATTCATTGGGATAATGTGATAAAAGCTAAGGATTTGTATCAAACCTTTGGACGTCAATACGAAAACATTCAGATTTATGG
TGAAGTTTCAGCTGGTACTGGTATCTGGGTTGGACATGAAAAACAAGAAACCATTAAATACCCAATACCAATTCCAGAAC
ATGATATTGCTCTTATTGTCAATGGTAATAGTATGGAACCTTTATTTTACAACGGTGACGTTATTTTTGTTAAAAAGACT
AAAGCTATCCATCACGGACAAATTATCGTTGTTATTGTAAATAATGAGGCATATGTCAAAAAACTCTACCGAAAAAACAA
AGAAATTCGACTCATCTCATTAAATCCAGATTATGATGACATCATTTTAAAAGAAGATGATACAATTGAAGTCATCGGAA
CGGTCATTACCTAA

Domains

Predicted by InterproScan.

Peptidase S24-like (Peptidase_S24)

(184-296)

Helix-turn-helix (HTH_3)

(22-70)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A090B2L0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  irvR Streptococcus mutans UA159

100

100

1

Multiple sequence alignment