Detailed information NTG0659159

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: MKI52_RS09615
• Genome accession: NZ_CP092581
• Coordinates: 1946373..1947416 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017128.1
• Uniprot ID: -
• Organism: Staphylococcus aureus strain VRMSSA-WC111
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1941373..1952416

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MKI52_RS09585 (MKI52_001901)	-	1941794..1943050 (-)	1257	WP_001795108.1	aminopeptidase	-
MKI52_RS09590 (MKI52_001902)	-	1943053..1943253 (-)	201	WP_000180460.1	DUF1128 family protein	-
MKI52_RS09595 (MKI52_001903)	-	1943400..1943864 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
MKI52_RS09600 (MKI52_001904)	-	1943871..1944146 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
MKI52_RS09605 (MKI52_001905)	-	1944424..1945641 (+)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
MKI52_RS09610 (MKI52_001906)	vraR	1945754..1946383 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
MKI52_RS09615 (MKI52_001907)	vraS	1946373..1947416 (-)	1044	WP_001017128.1	sensor histidine kinase	Regulator
MKI52_RS09620 (MKI52_001908)	liaF	1947413..1948114 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
MKI52_RS09625 (MKI52_001909)	-	1948129..1948515 (-)	387	WP_001110179.1	hypothetical protein	-
MKI52_RS09630 (MKI52_001910)	map	1948732..1949490 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
MKI52_RS09635 (MKI52_001911)	-	1950021..1951007 (+)	987	WP_000999717.1	aromatic acid exporter family protein	-
MKI52_RS09640 (MKI52_001912)	-	1951438..1951851 (-)	414	WP_001557448.1	hypothetical protein	-
MKI52_RS09645 (MKI52_001913)	-	1951880..1951990 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.56 Da
• Isoelectric Point: 6.2454

>NTDB_id=659159 MKI52_RS09615 WP_001017128.1 1946373..1947416(-) (vraS) [Staphylococcus aureus strain VRMSSA-WC111]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINKQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=659159 MKI52_RS09615 WP_001017128.1 1946373..1947416(-) (vraS) [Staphylococcus aureus strain VRMSSA-WC111]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATAAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	99.712	100	0.997