Detailed information    

insolico Bioinformatically predicted

Overview

Name   braS   Type   Regulator
Locus tag   MKI50_RS13900 Genome accession   NZ_CP092567
Coordinates   2758209..2759096 (-) Length   295 a.a.
NCBI ID   WP_000143425.1    Uniprot ID   A0A389PV50
Organism   Staphylococcus aureus strain MRSA-WC000     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2753209..2764096
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MKI50_RS13870 (MKI50_002751) - 2753227..2753319 (+) 93 WP_010956583.1 hypothetical protein -
  MKI50_RS13875 (MKI50_002752) - 2753427..2753924 (-) 498 WP_001065268.1 glutathione peroxidase -
  MKI50_RS13880 (MKI50_002753) - 2753934..2754194 (-) 261 WP_001791974.1 hypothetical protein -
  MKI50_RS13885 (MKI50_002754) - 2754576..2754689 (-) 114 Protein_2695 hypothetical protein -
  MKI50_RS13890 (MKI50_002755) - 2755349..2757349 (-) 2001 WP_000776751.1 ABC transporter permease -
  MKI50_RS13895 (MKI50_002756) - 2757346..2758101 (-) 756 WP_000923760.1 ABC transporter ATP-binding protein -
  MKI50_RS13900 (MKI50_002757) braS 2758209..2759096 (-) 888 WP_000143425.1 nisin susceptibility-associated two-component system sensor histidine kinase NsaS Regulator
  MKI50_RS13905 (MKI50_002758) braR 2759107..2759772 (-) 666 WP_000697877.1 nisin susceptibility-associated two-component system response regulator NsaR Regulator
  MKI50_RS13910 (MKI50_002759) - 2759798..2759998 (-) 201 WP_000604730.1 hypothetical protein -
  MKI50_RS13915 (MKI50_002760) - 2760196..2761620 (+) 1425 WP_000953755.1 alkaline phosphatase -
  MKI50_RS13920 (MKI50_002761) - 2761690..2761800 (+) 111 Protein_2702 hypothetical protein -
  MKI50_RS13925 (MKI50_002762) - 2761903..2762358 (-) 456 WP_000106185.1 MarR family winged helix-turn-helix transcriptional regulator -
  MKI50_RS13930 (MKI50_002763) - 2762603..2763364 (-) 762 WP_000323441.1 alpha/beta hydrolase family protein -

Sequence

Protein


Download         Length: 295 a.a.        Molecular weight: 34006.28 Da        Isoelectric Point: 6.0874

>NTDB_id=659013 MKI50_RS13900 WP_000143425.1 2758209..2759096(-) (braS) [Staphylococcus aureus strain MRSA-WC000]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLETALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide


Download         Length: 888 bp        

>NTDB_id=659013 MKI50_RS13900 WP_000143425.1 2758209..2759096(-) (braS) [Staphylococcus aureus strain MRSA-WC000]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAACTGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(191-294)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A389PV50

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  braS Staphylococcus aureus N315

100

100

1