Detailed information    

insolico Bioinformatically predicted

Overview

Name   braR   Type   Regulator
Locus tag   MKI50_RS13585 Genome accession   NZ_CP092567
Coordinates   2698554..2699228 (+) Length   224 a.a.
NCBI ID   WP_000866106.1    Uniprot ID   -
Organism   Staphylococcus aureus strain MRSA-WC000     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
IScluster/Tn 2690318..2708107 2698554..2699228 within 0


Gene organization within MGE regions


Location: 2690318..2708107
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MKI50_RS13545 (MKI50_002685) - 2690318..2691217 (-) 900 WP_000196698.1 Mph(C) family macrolide 2'-phosphotransferase -
  MKI50_RS13550 (MKI50_002686) msr(A) 2691316..2692782 (-) 1467 WP_000438874.1 ABC-F type ribosomal protection protein Msr(A) -
  MKI50_RS13555 (MKI50_002687) - 2693256..2693930 (+) 675 WP_001105960.1 IS6 family transposase -
  MKI50_RS13560 (MKI50_002688) - 2694224..2694397 (-) 174 WP_000044738.1 hypothetical protein -
  MKI50_RS13565 (MKI50_002689) - 2694441..2695061 (-) 621 WP_000941203.1 LysE family transporter -
  MKI50_RS13570 (MKI50_002690) - 2695066..2696037 (-) 972 WP_000053810.1 fatty acid desaturase family protein -
  MKI50_RS13575 (MKI50_002691) - 2696136..2697548 (+) 1413 WP_000526300.1 PLP-dependent aminotransferase family protein -
  MKI50_RS13580 (MKI50_002692) - 2697740..2698414 (+) 675 WP_001105960.1 IS6 family transposase -
  MKI50_RS13585 (MKI50_002693) braR 2698554..2699228 (+) 675 WP_000866106.1 response regulator transcription factor Regulator
  MKI50_RS13590 (MKI50_002694) - 2699225..2700106 (+) 882 Protein_2636 sensor histidine kinase -
  MKI50_RS13595 (MKI50_002695) - 2700222..2701151 (+) 930 WP_000793446.1 ABC transporter ATP-binding protein -
  MKI50_RS13600 (MKI50_002696) - 2701144..2701881 (+) 738 WP_000369394.1 ABC transporter permease -
  MKI50_RS13605 (MKI50_002697) - 2701895..2702071 (+) 177 Protein_2639 undecaprenyl-diphosphate phosphatase -
  MKI50_RS13610 (MKI50_002698) - 2702128..2702802 (+) 675 WP_001105960.1 IS6 family transposase -
  MKI50_RS13615 (MKI50_002699) - 2702943..2703578 (+) 636 Protein_2641 aminoglycoside 6-adenylyltransferase -
  MKI50_RS13620 (MKI50_002700) sat4 2703575..2704105 (+) 531 WP_000627289.1 streptothricin N-acetyltransferase Sat4 -
  MKI50_RS13625 (MKI50_002701) aph(3')-IIIa 2704198..2704992 (+) 795 WP_001096887.1 aminoglycoside O-phosphotransferase APH(3')-IIIa -
  MKI50_RS13630 - 2705268..2705399 (+) 132 Protein_2644 HTH domain-containing protein -
  MKI50_RS13635 - 2705475..2706220 (+) 746 Protein_2645 WYL domain-containing protein -
  MKI50_RS13640 (MKI50_002704) - 2706331..2706990 (+) 660 WP_000802831.1 RibD family protein -
  MKI50_RS13645 (MKI50_002705) - 2707433..2708107 (-) 675 WP_001105960.1 IS6 family transposase -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 25839.93 Da        Isoelectric Point: 4.9884

>NTDB_id=659012 MKI50_RS13585 WP_000866106.1 2698554..2699228(+) (braR) [Staphylococcus aureus strain MRSA-WC000]
MKVLIVEDDLVIGKMLAEELKKWQLEPILIEGFNHVMDAFNTNAPELVLLDINLPAFNGYHWCQEIRKVSTVPIIFISSR
NDSMDQVMAMQMGADDFIEKPFNMTVTITKIQALLRRTYDFTTQVNNLTVDDCELLLDAAKLKFNEETIDLTHTELQIMH
SLFQNKGKFVSRNALIEKCWESEHFIDDNTLAVNITRLRKKLQKLGLTDFIETKKNVGYRVGDV

Nucleotide


Download         Length: 675 bp        

>NTDB_id=659012 MKI50_RS13585 WP_000866106.1 2698554..2699228(+) (braR) [Staphylococcus aureus strain MRSA-WC000]
ATGAAAGTATTAATCGTAGAGGATGACTTAGTTATCGGGAAGATGCTTGCTGAAGAGCTCAAGAAGTGGCAGCTAGAACC
GATCTTAATAGAAGGTTTCAATCATGTAATGGATGCCTTCAACACGAATGCACCGGAACTTGTGTTACTCGATATTAATT
TACCTGCCTTCAATGGTTATCACTGGTGTCAGGAGATTCGTAAAGTTTCTACTGTACCGATTATATTTATTAGTTCGCGT
AACGACAGTATGGATCAAGTAATGGCGATGCAGATGGGTGCGGATGATTTCATTGAGAAGCCATTTAATATGACTGTTAC
AATTACTAAGATTCAAGCACTATTACGCCGCACGTATGATTTCACCACTCAAGTTAATAATTTAACAGTAGATGATTGCG
AGTTACTACTTGATGCAGCAAAGCTTAAATTTAATGAAGAAACCATAGACCTGACACACACTGAATTGCAAATCATGCAT
AGCTTATTCCAGAACAAGGGCAAATTCGTCAGTCGTAATGCGTTAATCGAAAAATGCTGGGAATCAGAACACTTCATTGA
TGACAATACGCTTGCTGTCAACATTACACGTTTACGCAAAAAGCTACAAAAACTAGGACTTACAGATTTTATCGAAACGA
AGAAAAATGTCGGATATCGTGTAGGTGACGTATGA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(147-220)

Response regulator receiver domain (Response_reg)

(3-111)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  braR Staphylococcus aureus N315

66.516

98.661

0.656