Detailed information NTG0659007

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: MKI50_RS10065
• Genome accession: NZ_CP092567
• Coordinates: 2014079..2015122 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017128.1
• Uniprot ID: -
• Organism: Staphylococcus aureus strain MRSA-WC000
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2009079..2020122

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MKI50_RS10035 (MKI50_001988)	-	2009500..2010756 (-)	1257	WP_001795108.1	aminopeptidase	-
MKI50_RS10040 (MKI50_001989)	-	2010759..2010959 (-)	201	WP_000180460.1	DUF1128 family protein	-
MKI50_RS10045 (MKI50_001990)	-	2011106..2011570 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
MKI50_RS10050 (MKI50_001991)	-	2011577..2011852 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
MKI50_RS10055 (MKI50_001992)	-	2012130..2013347 (+)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
MKI50_RS10060 (MKI50_001993)	vraR	2013460..2014089 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
MKI50_RS10065 (MKI50_001994)	vraS	2014079..2015122 (-)	1044	WP_001017128.1	sensor histidine kinase	Regulator
MKI50_RS10070 (MKI50_001995)	liaF	2015119..2015820 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
MKI50_RS10075 (MKI50_001996)	-	2015835..2016221 (-)	387	WP_001110179.1	hypothetical protein	-
MKI50_RS10080 (MKI50_001997)	map	2016438..2017196 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
MKI50_RS10085 (MKI50_001998)	-	2017727..2018713 (+)	987	WP_000999717.1	aromatic acid exporter family protein	-
MKI50_RS10090 (MKI50_001999)	-	2019144..2019557 (-)	414	WP_001557448.1	hypothetical protein	-
MKI50_RS10095 (MKI50_002000)	-	2019586..2019696 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.56 Da
• Isoelectric Point: 6.2454

>NTDB_id=659007 MKI50_RS10065 WP_001017128.1 2014079..2015122(-) (vraS) [Staphylococcus aureus strain MRSA-WC000]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINKQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=659007 MKI50_RS10065 WP_001017128.1 2014079..2015122(-) (vraS) [Staphylococcus aureus strain MRSA-WC000]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATAAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	99.712	100	0.997