Detailed information NTG0658963

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: MKI65_RS09740
• Genome accession: NZ_CP092565
• Coordinates: 1972184..1973227 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017128.1
• Uniprot ID: -
• Organism: Staphylococcus aureus strain MRSA-WC061
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1967184..1978227

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MKI65_RS09710 (MKI65_001927)	-	1967605..1968861 (-)	1257	WP_001795108.1	aminopeptidase	-
MKI65_RS09715 (MKI65_001928)	-	1968864..1969064 (-)	201	WP_000180460.1	DUF1128 family protein	-
MKI65_RS09720 (MKI65_001929)	-	1969211..1969675 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
MKI65_RS09725 (MKI65_001930)	-	1969682..1969957 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
MKI65_RS09730 (MKI65_001931)	-	1970235..1971452 (+)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
MKI65_RS09735 (MKI65_001932)	vraR	1971565..1972194 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
MKI65_RS09740 (MKI65_001933)	vraS	1972184..1973227 (-)	1044	WP_001017128.1	sensor histidine kinase	Regulator
MKI65_RS09745 (MKI65_001934)	liaF	1973224..1973925 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
MKI65_RS09750 (MKI65_001935)	-	1973940..1974326 (-)	387	WP_001110179.1	hypothetical protein	-
MKI65_RS09755 (MKI65_001936)	map	1974543..1975301 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
MKI65_RS09760 (MKI65_001937)	-	1975832..1976818 (+)	987	WP_000999717.1	aromatic acid exporter family protein	-
MKI65_RS09765 (MKI65_001938)	-	1977249..1977662 (-)	414	WP_001557448.1	hypothetical protein	-
MKI65_RS09770 (MKI65_001939)	-	1977691..1977801 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.56 Da
• Isoelectric Point: 6.2454

>NTDB_id=658963 MKI65_RS09740 WP_001017128.1 1972184..1973227(-) (vraS) [Staphylococcus aureus strain MRSA-WC061]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINKQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=658963 MKI65_RS09740 WP_001017128.1 1972184..1973227(-) (vraS) [Staphylococcus aureus strain MRSA-WC061]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATAAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	99.712	100	0.997