Detailed information NTG0658925

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: MKI59_RS13585
• Genome accession: NZ_CP092563
• Coordinates: 2717917..2718804 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143425.1
• Uniprot ID: A0A389PV50
• Organism: Staphylococcus aureus strain MRSA-WC090
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2712917..2723804

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MKI59_RS13555 (MKI59_002693)	-	2712936..2713028 (+)	93	WP_010956583.1	hypothetical protein	-
MKI59_RS13560 (MKI59_002694)	-	2713136..2713633 (-)	498	WP_001065268.1	glutathione peroxidase	-
MKI59_RS13565 (MKI59_002695)	-	2713643..2713903 (-)	261	WP_001791974.1	hypothetical protein	-
MKI59_RS13570 (MKI59_002696)	-	2714285..2714398 (-)	114	Protein_2634	hypothetical protein	-
MKI59_RS13575 (MKI59_002697)	-	2715057..2717057 (-)	2001	WP_000776751.1	ABC transporter permease	-
MKI59_RS13580 (MKI59_002698)	-	2717054..2717809 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
MKI59_RS13585 (MKI59_002699)	braS	2717917..2718804 (-)	888	WP_000143425.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
MKI59_RS13590 (MKI59_002700)	braR	2718815..2719480 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
MKI59_RS13595 (MKI59_002701)	-	2719506..2719706 (-)	201	WP_000604730.1	hypothetical protein	-
MKI59_RS13600 (MKI59_002702)	-	2719904..2721328 (+)	1425	WP_000953755.1	alkaline phosphatase	-
MKI59_RS13605 (MKI59_002703)	-	2721398..2721508 (+)	111	Protein_2641	hypothetical protein	-
MKI59_RS13610 (MKI59_002704)	-	2721611..2722066 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
MKI59_RS13615 (MKI59_002705)	-	2722311..2723072 (-)	762	WP_000323441.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34006.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=658925 MKI59_RS13585 WP_000143425.1 2717917..2718804(-) (braS) [Staphylococcus aureus strain MRSA-WC090]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLETALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=658925 MKI59_RS13585 WP_000143425.1 2717917..2718804(-) (braS) [Staphylococcus aureus strain MRSA-WC090]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAACTGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A389PV50

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	100	100	1