Detailed information NTG0658875

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: MKI54_RS09740
• Genome accession: NZ_CP092561
• Coordinates: 1971677..1972720 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017128.1
• Uniprot ID: -
• Organism: Staphylococcus aureus strain MRSA-WC101
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1966677..1977720

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MKI54_RS09710 (MKI54_001926)	-	1967098..1968354 (-)	1257	WP_001795108.1	aminopeptidase	-
MKI54_RS09715 (MKI54_001927)	-	1968357..1968557 (-)	201	WP_000180460.1	DUF1128 family protein	-
MKI54_RS09720 (MKI54_001928)	-	1968704..1969168 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
MKI54_RS09725 (MKI54_001929)	-	1969175..1969450 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
MKI54_RS09730 (MKI54_001930)	-	1969728..1970945 (+)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
MKI54_RS09735 (MKI54_001931)	vraR	1971058..1971687 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
MKI54_RS09740 (MKI54_001932)	vraS	1971677..1972720 (-)	1044	WP_001017128.1	sensor histidine kinase	Regulator
MKI54_RS09745 (MKI54_001933)	liaF	1972717..1973418 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
MKI54_RS09750 (MKI54_001934)	-	1973433..1973819 (-)	387	WP_001110179.1	hypothetical protein	-
MKI54_RS09755 (MKI54_001935)	map	1974036..1974794 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
MKI54_RS09760 (MKI54_001936)	-	1975325..1976311 (+)	987	WP_000999717.1	aromatic acid exporter family protein	-
MKI54_RS09765 (MKI54_001937)	-	1976742..1977155 (-)	414	WP_001557448.1	hypothetical protein	-
MKI54_RS09770 (MKI54_001938)	-	1977184..1977294 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.56 Da
• Isoelectric Point: 6.2454

>NTDB_id=658875 MKI54_RS09740 WP_001017128.1 1971677..1972720(-) (vraS) [Staphylococcus aureus strain MRSA-WC101]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINKQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=658875 MKI54_RS09740 WP_001017128.1 1971677..1972720(-) (vraS) [Staphylococcus aureus strain MRSA-WC101]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATAAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	99.712	100	0.997