Detailed information NTG0658837

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: MKI51_RS13580
• Genome accession: NZ_CP092558
• Coordinates: 2712860..2713747 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143425.1
• Uniprot ID: A0A389PV50
• Organism: Staphylococcus aureus strain VMRSA-WC052
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2707860..2718747

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MKI51_RS13550 (MKI51_002684)	-	2707879..2707971 (+)	93	WP_010956583.1	hypothetical protein	-
MKI51_RS13555 (MKI51_002685)	-	2708079..2708576 (-)	498	WP_001065268.1	glutathione peroxidase	-
MKI51_RS13560 (MKI51_002686)	-	2708586..2708846 (-)	261	WP_001791974.1	hypothetical protein	-
MKI51_RS13565 (MKI51_002687)	-	2709228..2709341 (-)	114	Protein_2636	hypothetical protein	-
MKI51_RS13570 (MKI51_002688)	-	2710000..2712000 (-)	2001	WP_000776751.1	ABC transporter permease	-
MKI51_RS13575 (MKI51_002689)	-	2711997..2712752 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
MKI51_RS13580 (MKI51_002690)	braS	2712860..2713747 (-)	888	WP_000143425.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
MKI51_RS13585 (MKI51_002691)	braR	2713758..2714423 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
MKI51_RS13590 (MKI51_002692)	-	2714449..2714649 (-)	201	WP_000604730.1	hypothetical protein	-
MKI51_RS13595 (MKI51_002693)	-	2714847..2716271 (+)	1425	WP_000953755.1	alkaline phosphatase	-
MKI51_RS13600 (MKI51_002694)	-	2716341..2716451 (+)	111	Protein_2643	hypothetical protein	-
MKI51_RS13605 (MKI51_002695)	-	2716554..2717009 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
MKI51_RS13610 (MKI51_002696)	-	2717254..2718015 (-)	762	WP_000323441.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34006.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=658837 MKI51_RS13580 WP_000143425.1 2712860..2713747(-) (braS) [Staphylococcus aureus strain VMRSA-WC052]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLETALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=658837 MKI51_RS13580 WP_000143425.1 2712860..2713747(-) (braS) [Staphylococcus aureus strain VMRSA-WC052]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAACTGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A389PV50

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	100	100	1