Detailed information NTG0658699

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: MKI53_RS09705
• Genome accession: NZ_CP092552
• Coordinates: 1969306..1970349 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017128.1
• Uniprot ID: -
• Organism: Staphylococcus aureus strain VMRSA-WC081
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1964306..1975349

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MKI53_RS09675 (MKI53_001922)	-	1964727..1965983 (-)	1257	WP_001795108.1	aminopeptidase	-
MKI53_RS09680 (MKI53_001923)	-	1965986..1966186 (-)	201	WP_000180460.1	DUF1128 family protein	-
MKI53_RS09685 (MKI53_001924)	-	1966333..1966797 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
MKI53_RS09690 (MKI53_001925)	-	1966804..1967079 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
MKI53_RS09695 (MKI53_001926)	-	1967357..1968574 (+)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
MKI53_RS09700 (MKI53_001927)	vraR	1968687..1969316 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
MKI53_RS09705 (MKI53_001928)	vraS	1969306..1970349 (-)	1044	WP_001017128.1	sensor histidine kinase	Regulator
MKI53_RS09710 (MKI53_001929)	liaF	1970346..1971047 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
MKI53_RS09715 (MKI53_001930)	-	1971062..1971448 (-)	387	WP_001110179.1	hypothetical protein	-
MKI53_RS09720 (MKI53_001931)	map	1971665..1972423 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
MKI53_RS09725 (MKI53_001932)	-	1972954..1973940 (+)	987	WP_000999717.1	aromatic acid exporter family protein	-
MKI53_RS09730 (MKI53_001933)	-	1974371..1974784 (-)	414	WP_001557448.1	hypothetical protein	-
MKI53_RS09735 (MKI53_001934)	-	1974813..1974923 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.56 Da
• Isoelectric Point: 6.2454

>NTDB_id=658699 MKI53_RS09705 WP_001017128.1 1969306..1970349(-) (vraS) [Staphylococcus aureus strain VMRSA-WC081]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINKQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=658699 MKI53_RS09705 WP_001017128.1 1969306..1970349(-) (vraS) [Staphylococcus aureus strain VMRSA-WC081]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATAAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	99.712	100	0.997