Detailed information NTG0658656

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: MKI63_RS09755
• Genome accession: NZ_CP092550
• Coordinates: 1972562..1973605 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017128.1
• Uniprot ID: -
• Organism: Staphylococcus aureus strain VMRSA-WC082
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1967562..1978605

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MKI63_RS09725 (MKI63_001927)	-	1967983..1969239 (-)	1257	WP_001795108.1	aminopeptidase	-
MKI63_RS09730 (MKI63_001928)	-	1969242..1969442 (-)	201	WP_000180460.1	DUF1128 family protein	-
MKI63_RS09735 (MKI63_001929)	-	1969589..1970053 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
MKI63_RS09740 (MKI63_001930)	-	1970060..1970335 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
MKI63_RS09745 (MKI63_001931)	-	1970613..1971830 (+)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
MKI63_RS09750 (MKI63_001932)	vraR	1971943..1972572 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
MKI63_RS09755 (MKI63_001933)	vraS	1972562..1973605 (-)	1044	WP_001017128.1	sensor histidine kinase	Regulator
MKI63_RS09760 (MKI63_001934)	liaF	1973602..1974303 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
MKI63_RS09765 (MKI63_001935)	-	1974318..1974704 (-)	387	WP_001110179.1	hypothetical protein	-
MKI63_RS09770 (MKI63_001936)	map	1974921..1975679 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
MKI63_RS09775 (MKI63_001937)	-	1976210..1977196 (+)	987	WP_000999717.1	aromatic acid exporter family protein	-
MKI63_RS09780 (MKI63_001938)	-	1977627..1978040 (-)	414	WP_001557448.1	hypothetical protein	-
MKI63_RS09785 (MKI63_001939)	-	1978069..1978179 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.56 Da
• Isoelectric Point: 6.2454

>NTDB_id=658656 MKI63_RS09755 WP_001017128.1 1972562..1973605(-) (vraS) [Staphylococcus aureus strain VMRSA-WC082]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINKQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=658656 MKI63_RS09755 WP_001017128.1 1972562..1973605(-) (vraS) [Staphylococcus aureus strain VMRSA-WC082]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATAAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	99.712	100	0.997