Detailed information NTG0658618

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: MKI66_RS13620
• Genome accession: NZ_CP092547
• Coordinates: 2717831..2718718 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143425.1
• Uniprot ID: A0A389PV50
• Organism: Staphylococcus aureus strain VMRSA-WC083
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2712831..2723718

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MKI66_RS13590 (MKI66_002691)	-	2712850..2712942 (+)	93	WP_010956583.1	hypothetical protein	-
MKI66_RS13595 (MKI66_002692)	-	2713050..2713547 (-)	498	WP_001065268.1	glutathione peroxidase	-
MKI66_RS13600 (MKI66_002693)	-	2713557..2713817 (-)	261	WP_001791974.1	hypothetical protein	-
MKI66_RS13605 (MKI66_002694)	-	2714199..2714312 (-)	114	Protein_2642	hypothetical protein	-
MKI66_RS13610 (MKI66_002695)	-	2714971..2716971 (-)	2001	WP_000776751.1	ABC transporter permease	-
MKI66_RS13615 (MKI66_002696)	-	2716968..2717723 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
MKI66_RS13620 (MKI66_002697)	braS	2717831..2718718 (-)	888	WP_000143425.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
MKI66_RS13625 (MKI66_002698)	braR	2718729..2719394 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
MKI66_RS13630 (MKI66_002699)	-	2719420..2719620 (-)	201	WP_000604730.1	hypothetical protein	-
MKI66_RS13635 (MKI66_002700)	-	2719818..2721242 (+)	1425	WP_000953755.1	alkaline phosphatase	-
MKI66_RS13640 (MKI66_002701)	-	2721312..2721422 (+)	111	Protein_2649	hypothetical protein	-
MKI66_RS13645 (MKI66_002702)	-	2721525..2721980 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
MKI66_RS13650 (MKI66_002703)	-	2722225..2722986 (-)	762	WP_000323441.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34006.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=658618 MKI66_RS13620 WP_000143425.1 2717831..2718718(-) (braS) [Staphylococcus aureus strain VMRSA-WC083]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLETALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=658618 MKI66_RS13620 WP_000143425.1 2717831..2718718(-) (braS) [Staphylococcus aureus strain VMRSA-WC083]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAACTGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A389PV50

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	100	100	1