Detailed information    

insolico Bioinformatically predicted

Overview

Name   braR   Type   Regulator
Locus tag   MKI66_RS13240 Genome accession   NZ_CP092547
Coordinates   2645954..2646628 (-) Length   224 a.a.
NCBI ID   WP_000866106.1    Uniprot ID   -
Organism   Staphylococcus aureus strain VMRSA-WC083     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
IScluster/Tn 2639234..2654864 2645954..2646628 within 0


Gene organization within MGE regions


Location: 2639234..2654864
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MKI66_RS13195 (MKI66_002611) - 2639234..2639908 (+) 675 WP_001105987.1 IS6-like element IS257 family transposase -
  MKI66_RS13200 (MKI66_002612) aph(3')-IIIa 2640190..2640984 (-) 795 WP_001096887.1 aminoglycoside O-phosphotransferase APH(3')-IIIa -
  MKI66_RS13205 (MKI66_002613) sat4 2641077..2641607 (-) 531 WP_000627289.1 streptothricin N-acetyltransferase Sat4 -
  MKI66_RS13210 (MKI66_002614) - 2641604..2642239 (-) 636 Protein_2563 aminoglycoside 6-adenylyltransferase -
  MKI66_RS13215 (MKI66_002615) - 2642380..2643054 (-) 675 WP_001105960.1 IS6 family transposase -
  MKI66_RS13220 (MKI66_002616) - 2643111..2643287 (-) 177 Protein_2565 undecaprenyl-diphosphate phosphatase -
  MKI66_RS13225 (MKI66_002617) - 2643301..2644038 (-) 738 WP_000369394.1 ABC transporter permease -
  MKI66_RS13230 (MKI66_002618) - 2644031..2644960 (-) 930 WP_000793446.1 ABC transporter ATP-binding protein -
  MKI66_RS13235 (MKI66_002619) - 2645076..2645957 (-) 882 Protein_2568 sensor histidine kinase -
  MKI66_RS13240 (MKI66_002620) braR 2645954..2646628 (-) 675 WP_000866106.1 response regulator transcription factor Regulator
  MKI66_RS13245 (MKI66_002621) - 2646768..2647442 (-) 675 WP_001105960.1 IS6 family transposase -
  MKI66_RS13250 (MKI66_002622) - 2647634..2649046 (-) 1413 WP_000526300.1 PLP-dependent aminotransferase family protein -
  MKI66_RS13255 (MKI66_002623) - 2649145..2650116 (+) 972 WP_000053810.1 fatty acid desaturase family protein -
  MKI66_RS13260 (MKI66_002624) - 2650121..2650741 (+) 621 WP_000941203.1 LysE family transporter -
  MKI66_RS13265 (MKI66_002625) - 2650785..2650958 (+) 174 WP_000044738.1 hypothetical protein -
  MKI66_RS13270 (MKI66_002626) - 2651252..2651926 (-) 675 WP_001105960.1 IS6 family transposase -
  MKI66_RS13275 (MKI66_002627) msr(A) 2652400..2653866 (+) 1467 WP_000438874.1 ABC-F type ribosomal protection protein Msr(A) -
  MKI66_RS13280 (MKI66_002628) - 2653965..2654864 (+) 900 WP_000196698.1 Mph(C) family macrolide 2'-phosphotransferase -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 25839.93 Da        Isoelectric Point: 4.9884

>NTDB_id=658617 MKI66_RS13240 WP_000866106.1 2645954..2646628(-) (braR) [Staphylococcus aureus strain VMRSA-WC083]
MKVLIVEDDLVIGKMLAEELKKWQLEPILIEGFNHVMDAFNTNAPELVLLDINLPAFNGYHWCQEIRKVSTVPIIFISSR
NDSMDQVMAMQMGADDFIEKPFNMTVTITKIQALLRRTYDFTTQVNNLTVDDCELLLDAAKLKFNEETIDLTHTELQIMH
SLFQNKGKFVSRNALIEKCWESEHFIDDNTLAVNITRLRKKLQKLGLTDFIETKKNVGYRVGDV

Nucleotide


Download         Length: 675 bp        

>NTDB_id=658617 MKI66_RS13240 WP_000866106.1 2645954..2646628(-) (braR) [Staphylococcus aureus strain VMRSA-WC083]
ATGAAAGTATTAATCGTAGAGGATGACTTAGTTATCGGGAAGATGCTTGCTGAAGAGCTCAAGAAGTGGCAGCTAGAACC
GATCTTAATAGAAGGTTTCAATCATGTAATGGATGCCTTCAACACGAATGCACCGGAACTTGTGTTACTCGATATTAATT
TACCTGCCTTCAATGGTTATCACTGGTGTCAGGAGATTCGTAAAGTTTCTACTGTACCGATTATATTTATTAGTTCGCGT
AACGACAGTATGGATCAAGTAATGGCGATGCAGATGGGTGCGGATGATTTCATTGAGAAGCCATTTAATATGACTGTTAC
AATTACTAAGATTCAAGCACTATTACGCCGCACGTATGATTTCACCACTCAAGTTAATAATTTAACAGTAGATGATTGCG
AGTTACTACTTGATGCAGCAAAGCTTAAATTTAATGAAGAAACCATAGACCTGACACACACTGAATTGCAAATCATGCAT
AGCTTATTCCAGAACAAGGGCAAATTCGTCAGTCGTAATGCGTTAATCGAAAAATGCTGGGAATCAGAACACTTCATTGA
TGACAATACGCTTGCTGTCAACATTACACGTTTACGCAAAAAGCTACAAAAACTAGGACTTACAGATTTTATCGAAACGA
AGAAAAATGTCGGATATCGTGTAGGTGACGTATGA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(147-220)

Response regulator receiver domain (Response_reg)

(3-111)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  braR Staphylococcus aureus N315

66.516

98.661

0.656