Detailed information NTG0658577

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: MKI60_RS13585
• Genome accession: NZ_CP092544
• Coordinates: 2716739..2717626 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143425.1
• Uniprot ID: A0A389PV50
• Organism: Staphylococcus aureus strain VMRSA-WC102
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2711739..2722626

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MKI60_RS13555 (MKI60_002692)	-	2711758..2711850 (+)	93	WP_010956583.1	hypothetical protein	-
MKI60_RS13560 (MKI60_002693)	-	2711958..2712455 (-)	498	WP_001065268.1	glutathione peroxidase	-
MKI60_RS13565 (MKI60_002694)	-	2712465..2712725 (-)	261	WP_001791974.1	hypothetical protein	-
MKI60_RS13570 (MKI60_002695)	-	2713107..2713220 (-)	114	Protein_2633	hypothetical protein	-
MKI60_RS13575 (MKI60_002696)	-	2713879..2715879 (-)	2001	WP_000776751.1	ABC transporter permease	-
MKI60_RS13580 (MKI60_002697)	-	2715876..2716631 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
MKI60_RS13585 (MKI60_002698)	braS	2716739..2717626 (-)	888	WP_000143425.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
MKI60_RS13590 (MKI60_002699)	braR	2717637..2718302 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
MKI60_RS13595 (MKI60_002700)	-	2718328..2718528 (-)	201	WP_000604730.1	hypothetical protein	-
MKI60_RS13600 (MKI60_002701)	-	2718726..2720150 (+)	1425	WP_000953755.1	alkaline phosphatase	-
MKI60_RS13605 (MKI60_002702)	-	2720220..2720330 (+)	111	Protein_2640	hypothetical protein	-
MKI60_RS13610 (MKI60_002703)	-	2720433..2720888 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
MKI60_RS13615 (MKI60_002704)	-	2721133..2721894 (-)	762	WP_000323441.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34006.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=658577 MKI60_RS13585 WP_000143425.1 2716739..2717626(-) (braS) [Staphylococcus aureus strain VMRSA-WC102]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLETALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=658577 MKI60_RS13585 WP_000143425.1 2716739..2717626(-) (braS) [Staphylococcus aureus strain VMRSA-WC102]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAACTGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A389PV50

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	100	100	1