Detailed information NTG0658571

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: MKI60_RS09745
• Genome accession: NZ_CP092544
• Coordinates: 1972575..1973618 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017128.1
• Uniprot ID: -
• Organism: Staphylococcus aureus strain VMRSA-WC102
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1967575..1978618

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MKI60_RS09715 (MKI60_001928)	-	1967996..1969252 (-)	1257	WP_001795108.1	aminopeptidase	-
MKI60_RS09720 (MKI60_001929)	-	1969255..1969455 (-)	201	WP_000180460.1	DUF1128 family protein	-
MKI60_RS09725 (MKI60_001930)	-	1969602..1970066 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
MKI60_RS09730 (MKI60_001931)	-	1970073..1970348 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
MKI60_RS09735 (MKI60_001932)	-	1970626..1971843 (+)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
MKI60_RS09740 (MKI60_001933)	vraR	1971956..1972585 (-)	630	WP_242413776.1	two-component system response regulator VraR	Regulator
MKI60_RS09745 (MKI60_001934)	vraS	1972575..1973618 (-)	1044	WP_001017128.1	sensor histidine kinase	Regulator
MKI60_RS09750 (MKI60_001935)	liaF	1973615..1974316 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
MKI60_RS09755 (MKI60_001936)	-	1974331..1974717 (-)	387	WP_001110179.1	hypothetical protein	-
MKI60_RS09760 (MKI60_001937)	map	1974934..1975692 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
MKI60_RS09765 (MKI60_001938)	-	1976223..1977209 (+)	987	WP_000999717.1	aromatic acid exporter family protein	-
MKI60_RS09770 (MKI60_001939)	-	1977640..1978053 (-)	414	WP_001557448.1	hypothetical protein	-
MKI60_RS09775 (MKI60_001940)	-	1978082..1978192 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.56 Da
• Isoelectric Point: 6.2454

>NTDB_id=658571 MKI60_RS09745 WP_001017128.1 1972575..1973618(-) (vraS) [Staphylococcus aureus strain VMRSA-WC102]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINKQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=658571 MKI60_RS09745 WP_001017128.1 1972575..1973618(-) (vraS) [Staphylococcus aureus strain VMRSA-WC102]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATAAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	99.712	100	0.997