Detailed information NTG0658485

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: MKI67_RS09750
• Genome accession: NZ_CP092540
• Coordinates: 1972592..1973635 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017128.1
• Uniprot ID: -
• Organism: Staphylococcus aureus strain VMRSA-WC121
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1967592..1978635

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MKI67_RS09720 (MKI67_001928)	-	1968013..1969269 (-)	1257	WP_001795108.1	aminopeptidase	-
MKI67_RS09725 (MKI67_001929)	-	1969272..1969472 (-)	201	WP_000180460.1	DUF1128 family protein	-
MKI67_RS09730 (MKI67_001930)	-	1969619..1970083 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
MKI67_RS09735 (MKI67_001931)	-	1970090..1970365 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
MKI67_RS09740 (MKI67_001932)	-	1970643..1971860 (+)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
MKI67_RS09745 (MKI67_001933)	vraR	1971973..1972602 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
MKI67_RS09750 (MKI67_001934)	vraS	1972592..1973635 (-)	1044	WP_001017128.1	sensor histidine kinase	Regulator
MKI67_RS09755 (MKI67_001935)	liaF	1973632..1974333 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
MKI67_RS09760 (MKI67_001936)	-	1974348..1974734 (-)	387	WP_001110179.1	hypothetical protein	-
MKI67_RS09765 (MKI67_001937)	map	1974951..1975709 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
MKI67_RS09770 (MKI67_001938)	-	1976240..1977226 (+)	987	WP_000999717.1	aromatic acid exporter family protein	-
MKI67_RS09775 (MKI67_001939)	-	1977657..1978070 (-)	414	WP_242414258.1	hypothetical protein	-
MKI67_RS09780 (MKI67_001940)	-	1978099..1978209 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.56 Da
• Isoelectric Point: 6.2454

>NTDB_id=658485 MKI67_RS09750 WP_001017128.1 1972592..1973635(-) (vraS) [Staphylococcus aureus strain VMRSA-WC121]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINKQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=658485 MKI67_RS09750 WP_001017128.1 1972592..1973635(-) (vraS) [Staphylococcus aureus strain VMRSA-WC121]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATAAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	99.712	100	0.997